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The application of the Multi-modal Large Language Models (MLLMs) in medical clinical scenarios remains underexplored. Previous benchmarks only focus on the capacity of the MLLMs in medical visual question-answering (VQA) or report…

Computation and Language · Computer Science 2024-08-19 Hongcheng Liu , Yusheng Liao , Siqv Ou , Yuhao Wang , Heyang Liu , Yanfeng Wang , Yu Wang

The Model Context Protocol (MCP) is rapidly emerging as the middleware for LLM-based applications, offering a standardized interface for tool integration. However, its built-in security mechanisms are minimal: while schemas and declarations…

Cryptography and Security · Computer Science 2025-12-04 Biwei Yan , Yue Zhang , Minghui Xu , Hao Wu , Yechao Zhang , Kun Li , Guoming Zhang , Xiuzhen Cheng

Advances in large language models (LLMs) and real-time speech recognition now make it possible to issue any graphical user interface (GUI) action through natural language and receive the corresponding system response directly through the…

Human-Computer Interaction · Computer Science 2025-10-10 Hans G. W. van Dam

Answering financial questions is often treated as an information retrieval problem. In practice, however, much of the relevant information is already available in curated vendor systems, especially for quantitative analysis. We study…

Information Retrieval · Computer Science 2026-03-24 Sasan Mansouri , Edoardo Pilla , Mark Wahrenburg , Fabian Woebbeking

The Model Context Protocol (MCP) represents a significant advancement in AI-tool integration, enabling seamless communication between AI agents and external services. However, this connectivity introduces novel attack vectors that remain…

Cryptography and Security · Computer Science 2025-07-29 Nicola Croce , Tobin South

Rapid advancements in imaging techniques and analytical methods over the past decade have revolutionized our ability to comprehensively probe the biological world at multiple scales, pinpointing the type, quantity, location, and even…

Artificial Intelligence · Computer Science 2025-10-02 Shanghang Zhang , Gaole Dai , Tiejun Huang , Jianxu Chen

The Model Context Protocol (MCP) has rapidly become a de facto standard for connecting LLM-based agents with external tools via reusable MCP servers. In practice, however, server selection and onboarding rely heavily on free-text tool…

Software Engineering · Computer Science 2026-02-24 Peiran Wang , Ying Li , Yuqiang Sun , Chengwei Liu , Yang Liu , Yuan Tian

Heterogeneous, interconnected, systems-level, molecular data have become increasingly available and key in precision medicine. We need to utilize them to better stratify patients into risk groups, discover new biomarkers and targets,…

Other Quantitative Biology · Quantitative Biology 2024-05-17 Natasa Przulj , Noel Malod-Dognin

Large Language Models (LLMs) impose massive computational demands, driving the need for scalable multi-chiplet accelerators. However, existing mapping space exploration efforts for such accelerators primarily focus on traditional…

Hardware Architecture · Computer Science 2026-04-02 Boyu Li , Zongwei Zhu , Yi Xiong , Qianyue Cao , Jiawei Geng , Xiaonan Zhang , Xi Li

We introduce SCP: the Science Context Protocol, an open-source standard designed to accelerate discovery by enabling a global network of autonomous scientific agents. SCP is built on two foundational pillars: (1) Unified Resource…

The Model Context Protocol (MCP) standardizes how AI agents discover and invoke external tools, with over 10,000 active servers and 97 million monthly SDK downloads as of early 2026. Yet MCP does not yet standardize how agents safely…

Software Engineering · Computer Science 2026-04-16 Vasundra Srinivasan

Epistemic AI accelerates biomedical discovery by finding hidden connections in the network of biomedical knowledge. The Epistemic AI web-based software platform embodies the concept of knowledge mapping, an interactive process that relies…

Artificial Intelligence · Computer Science 2022-04-04 Da Chen Emily Koo , Heather Bowling , Kenneth Ashworth , David J. Heeger , Stefano Pacifico

Recent advancements in Large Language Models (LLMs) are transforming biology, computer science, engineering, and every day life. However, integrating the wide array of computational tools, databases, and scientific literature continues to…

The integration of Large Language Models (LLMs) into scientific workflows presents exciting opportunities to accelerate biomedical discovery. However, the reactive nature of LLMs, which respond only when prompted, limits their effectiveness…

Computation and Language · Computer Science 2026-04-20 Yang Wu , Jinhong Yu , Jingwei Xiong , Zhimin Tao , Xiaozhong Liu

Multi-agent systems represent a significant advancement in artificial intelligence, enabling complex problem-solving through coordinated specialized agents. However, these systems face fundamental challenges in context management,…

Multiagent Systems · Computer Science 2025-05-01 Naveen Krishnan

Advances in bioinformatics are primarily due to new algorithms for processing diverse biological data sources. While sophisticated alignment algorithms have been pivotal in analyzing biological sequences, deep learning has substantially…

Large language models (LLMs) are a class of artificial intelligence models based on deep learning, which have great performance in various tasks, especially in natural language processing (NLP). Large language models typically consist of…

Quantitative Methods · Quantitative Biology 2025-02-04 Jiajia Liu , Mengyuan Yang , Yankai Yu , Haixia Xu , Tiangang Wang , Kang Li , Xiaobo Zhou

AI development environments are evolving into observability first platforms that integrate real time telemetry, prompt traces, and evaluation feedback into the developer workflow. This paper introduces telemetry aware integrated development…

Software Engineering · Computer Science 2025-06-16 Vincent Koc , Jacques Verre , Douglas Blank , Abigail Morgan

Agentic AI is transforming security by automating many tasks being performed manually. While initial agentic approaches employed a monolithic architecture, the Model-Context-Protocol has now enabled a remote-procedure call (RPC) paradigm to…

Cryptography and Security · Computer Science 2025-10-07 Zachary Ezetta , Wu-chang Feng

In rural regions of several developing countries, access to quality healthcare, medical infrastructure, and professional diagnosis is largely unavailable. Many of these regions are gradually gaining access to internet infrastructure,…

Computation and Language · Computer Science 2021-06-03 Vishal Vinod , Susmit Agrawal , Vipul Gaurav , Pallavi R , Savita Choudhary