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This article introduces differentially private log-location-scale (DP-LLS) regression models, which incorporate differential privacy into LLS regression through the functional mechanism. The proposed models are established by injecting…

Machine Learning · Statistics 2024-04-16 Jiewen Sheng , Xiaolei Fang

Large Language Model (LLM)-based recommendation systems leverage powerful language models to generate personalized suggestions by processing user interactions and preferences. Unlike traditional recommendation systems that rely on…

Information Retrieval · Computer Science 2025-05-05 Tina Khezresmaeilzadeh , Jiang Zhang , Dimitrios Andreadis , Konstantinos Psounis

In-context learning (ICL) enables Large Language Models (LLMs) to adapt to new tasks with only a small set of examples at inference time, thereby avoiding task-specific fine-tuning. However, in-context examples may contain privacy-sensitive…

Machine Learning · Computer Science 2026-02-06 Rob Romijnders , Mohammad Mahdi Derakhshani , Jonathan Petit , Max Welling , Christos Louizos , Yuki M. Asano

Differentially private (DP) synthetic data generation plays a pivotal role in developing large language models (LLMs) on private data, where data owners cannot provide eyes-on access to individual examples. Generating DP synthetic data…

Positioned between pre-training and user deployment, aligning large language models (LLMs) through reinforcement learning (RL) has emerged as a prevailing strategy for training instruction following-models such as ChatGPT. In this work, we…

Machine Learning · Computer Science 2024-05-06 Fan Wu , Huseyin A. Inan , Arturs Backurs , Varun Chandrasekaran , Janardhan Kulkarni , Robert Sim

Large language model (LLM) systems are increasingly used to support high-stakes decision-making, but they typically perform worse when the available evidence is internally inconsistent. Such a scenario exists in real-world healthcare…

Computation and Language · Computer Science 2026-04-02 Haochen Liu , Weien Li , Rui Song , Zeyu Li , Chun Jason Xue , Xiao-Yang Liu , Sam Nallaperuma , Xue Liu , Ye Yuan

Differential privacy (DP) is applied when fine-tuning pre-trained large language models (LLMs) to limit leakage of training examples. While most DP research has focused on improving a model's privacy-utility tradeoff, some find that DP can…

Computation and Language · Computer Science 2024-10-25 Md. Khairul Islam , Andrew Wang , Tianhao Wang , Yangfeng Ji , Judy Fox , Jieyu Zhao

Clinically acquired brain MRIs and radiology reports are valuable but underutilized resources due to the challenges of manual analysis and data heterogeneity. We developed fine-tuned language models (LMs) to classify brain MRI reports as…

We study the inherent trade-offs in minimizing privacy risks and maximizing utility, while maintaining high computational efficiency, when fine-tuning large language models (LLMs). A number of recent works in privacy research have attempted…

Artificial Intelligence · Computer Science 2026-02-10 Soumi Das , Camila Kolling , Mohammad Aflah Khan , Mahsa Amani , Bishwamittra Ghosh , Qinyuan Wu , Till Speicher , Krishna P. Gummadi

Large language models (LLMs) are trained on vast datasets that may contain sensitive information. Differential privacy (DP), the de facto standard for formal privacy guarantees, provides a principled framework for training LLMs with…

Machine Learning · Computer Science 2026-05-26 Enayat Ullah , Sai Aparna Aketi , Devansh Gupta , Huanyu Zhang , Meisam Razaviyayn

Large language models (LLMs) are increasingly being used in privacy pipelines to detect and remedy sensitive data leakage. These solutions often rely on the premise that LLMs can reliably recognize human names, one of the most important…

Cryptography and Security · Computer Science 2026-04-28 Dzung Pham , Peter Kairouz , Niloofar Mireshghallah , Eugene Bagdasarian , Chau Minh Pham , Amir Houmansadr

The unstructured nature of clinical notes within electronic health records often conceals vital patient-related information, making it challenging to access or interpret. To uncover this hidden information, specialized Natural Language…

Large language models trained on clinical text risk exposing sensitive patient information, yet differential privacy (DP) methods often severely degrade the diagnostic accuracy needed for deployment. Despite rapid progress in DP…

Machine Learning · Computer Science 2025-11-20 Mathieu Dufour , Andrew Duncan

Large Language Models (LLMs) are increasingly deployed in mental health contexts, from structured therapeutic support tools to informal chat-based well-being assistants. While these systems increase accessibility, scalability, and…

Human-Computer Interaction · Computer Science 2025-10-14 Soraya S. Anvari , Rina R. Wehbe

The recent advances in large language models (LLMs) have significantly expanded their applications across various fields such as language generation, summarization, and complex question answering. However, their application to privacy…

Computation and Language · Computer Science 2025-02-17 Yang Liu , Xichou Zhu , Zhou Shen , Yi Liu , Min Li , Yujun Chen , Benzi John , Zhenzhen Ma , Tao Hu , Zhi Li , Bolong Yang , Manman Wang , Zongxing Xie , Peng Liu , Dan Cai , Junhui Wang

Background: The radiation oncology clinical practice involves many steps relying on the dynamic interplay of abundant text data. Large language models have displayed remarkable capabilities in processing complex text information. But their…

Language model alignment is crucial for ensuring that large language models (LLMs) align with human preferences, yet it often involves sensitive user data, raising significant privacy concerns. While prior work has integrated differential…

Cryptography and Security · Computer Science 2025-05-15 Keyu Chen , Hao Tang , Qinglin Liu , Yizhao Xu

The recent swift development of LLMs like GPT-4, Gemini, and GPT-3.5 offers a transformative opportunity in medicine and healthcare, especially in digital diagnostics. This study evaluates each model diagnostic abilities by interpreting a…

Computation and Language · Computer Science 2024-05-14 Gaurav Kumar Gupta , Aditi Singh , Sijo Valayakkad Manikandan , Abul Ehtesham

Writing radiology reports from medical images requires a high level of domain expertise. It is time-consuming even for trained radiologists and can be error-prone for inexperienced radiologists. It would be appealing to automate this task…

Computer Vision and Pattern Recognition · Computer Science 2023-12-05 Yuzhe Lu , Sungmin Hong , Yash Shah , Panpan Xu

Privacy-preserving adaptation of Large Language Models (LLMs) in sensitive domains (e.g., mental health) requires balancing strict confidentiality with model utility and safety. We propose FedMentor, a federated fine-tuning framework that…

Cryptography and Security · Computer Science 2026-01-27 Nobin Sarwar , Shubhashis Roy Dipta
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