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Generating physician letters is a time-consuming task in daily clinical practice. This study investigates local fine-tuning of large language models (LLMs), specifically LLaMA models, for physician letter generation in a privacy-preserving…

The performance of modern machine learning systems depends on access to large, high-quality datasets, often sourced from user-generated content or proprietary, domain-specific corpora. However, these rich datasets inherently contain…

Cryptography and Security · Computer Science 2025-08-28 Zhan Shi , Yefeng Yuan , Yuhong Liu , Liang Cheng , Yi Fang

Fine-tuning large vision models (LVMs) and large language models (LLMs) under differentially private federated learning (DPFL) is hindered by a fundamental privacy-utility trade-off. Low-Rank Adaptation (LoRA), a promising…

Machine Learning · Computer Science 2026-04-21 Jin Liu , Yinbin Miao , Ning Xi , Junkang Liu

Accurate privacy evaluation of textual data remains a critical challenge in privacy-preserving natural language processing. Recent work has shown that large language models (LLMs) can serve as reliable privacy evaluators, achieving strong…

Computation and Language · Computer Science 2026-04-01 Gabriel Loiseau , Damien Sileo , Damien Riquet , Maxime Meyer , Marc Tommasi

Generating tabular data under differential privacy (DP) protection ensures theoretical privacy guarantees but poses challenges for training machine learning models, primarily due to the need to capture complex structures under noisy…

Machine Learning · Computer Science 2025-04-30 Tejumade Afonja , Hui-Po Wang , Raouf Kerkouche , Mario Fritz

In-context learning (ICL) enables large language models (LLMs) to adapt to new tasks by conditioning on demonstrations of question-answer pairs and it has been shown to have comparable performance to costly model retraining and fine-tuning.…

Cryptography and Security · Computer Science 2024-03-12 Alycia N. Carey , Karuna Bhaila , Kennedy Edemacu , Xintao Wu

Despite significant progress in applying large language models (LLMs) to the medical domain, several limitations still prevent them from practical applications. Among these are the constraints on model size and the lack of cohort-specific…

Artificial Intelligence · Computer Science 2024-09-26 Yishu Wei , Xindi Wang , Hanley Ong , Yiliang Zhou , Adam Flanders , George Shih , Yifan Peng

Large language models (LLMs) have demonstrated impressive performance across various domains. However, for clinical diagnosis, higher expectations are required for LLM's reliability and sensitivity: thinking like physicians and remaining…

Computation and Language · Computer Science 2025-04-21 Chenwei Yan , Xiangling Fu , Yuxuan Xiong , Tianyi Wang , Siu Cheung Hui , Ji Wu , Xien Liu

This position paper investigates the integration of Differential Privacy (DP) in the training of Mixture of Experts (MoE) models within the field of natural language processing. As Large Language Models (LLMs) scale to billions of…

Cryptography and Security · Computer Science 2024-02-13 Pierre Tholoniat , Huseyin A. Inan , Janardhan Kulkarni , Robert Sim

Differential privacy (DP) is the de facto privacy standard against privacy leakage attacks, including many recently discovered ones against large language models (LLMs). However, we discovered that LLMs could reconstruct the altered/removed…

Cryptography and Security · Computer Science 2025-09-19 Shuchao Pang , Zhigang Lu , Haichen Wang , Peng Fu , Yongbin Zhou , Minhui Xue

We investigate the effectiveness of fine-tuning large language models (LLMs) on small medical datasets for text classification and named entity recognition tasks. Using a German cardiology report dataset and the i2b2 Smoking Challenge…

Computation and Language · Computer Science 2025-03-28 Noah Losch , Lucas Plagwitz , Antonius Büscher , Julian Varghese

Large Language Models (LLMs) have demonstrated surprising performance across various natural language processing tasks. Recently, medical LLMs enhanced with domain-specific knowledge have exhibited excellent capabilities in medical…

Computation and Language · Computer Science 2024-09-24 Jinqiang Wang , Huansheng Ning , Yi Peng , Qikai Wei , Daniel Tesfai , Wenwei Mao , Tao Zhu , Runhe Huang

Large Language Models (LLMs) have demonstrated remarkable capabilities across diverse natural language processing tasks, but their tendency to memorize training data poses significant privacy risks, particularly during fine-tuning…

Computation and Language · Computer Science 2025-08-21 Badrinath Ramakrishnan , Akshaya Balaji

As sufficient data are not always publically accessible for model training, researchers exploit limited data with advanced learning algorithms or expand the dataset via data augmentation (DA). Conducting DA in private domain requires…

Computation and Language · Computer Science 2024-02-27 Yiping Song , Juhua Zhang , Zhiliang Tian , Yuxin Yang , Minlie Huang , Dongsheng Li

The recent success of Large Language Models (LLMs) has gained significant attention in both academia and industry. Substantial efforts have been made to enhance the zero- and few-shot generalization capabilities of open-source LLMs through…

Computation and Language · Computer Science 2023-10-03 Zongxi Li , Xianming Li , Yuzhang Liu , Haoran Xie , Jing Li , Fu-lee Wang , Qing Li , Xiaoqin Zhong

Large Language Models (LLMs) have demonstrated advanced capabilities in both text generation and comprehension, and their application to data archives might facilitate the privatization of sensitive information about the data subjects. In…

Cryptography and Security · Computer Science 2025-04-08 Stefano Cirillo , Domenico Desiato , Giuseppe Polese , Monica Maria Lucia Sebillo , Giandomenico Solimando

With LLMs increasingly deployed in corporate data management, it is crucial to ensure that these models do not leak sensitive information. In the context of corporate data management, the concept of sensitivity awareness has been…

Cryptography and Security · Computer Science 2026-01-30 Dren Fazlija , Iyiola E. Olatunji , Daniel Kudenko , Sandipan Sikdar

The rise of chronic diseases and pandemics like COVID-19 has emphasized the need for effective patient data processing while ensuring privacy through anonymization and de-identification of protected health information (PHI). Anonymized data…

Computation and Language · Computer Science 2024-12-17 Murat Gunay , Bunyamin Keles , Raife Hizlan

When users submit queries to Large Language Models (LLMs), their prompts can often contain sensitive data, forcing a difficult choice: Send the query to a powerful proprietary LLM providers to achieving state-of-the-art performance and risk…

Cryptography and Security · Computer Science 2026-04-21 Zheng Hui , Yijiang River Dong , Sanhanat Sivapiromrat , Ehsan Shareghi , Nigel Collier

Differential privacy (DP) has a wide range of applications for protecting data privacy, but designing and verifying DP algorithms requires expert-level reasoning, creating a high barrier for non-expert practitioners. Prior works either rely…

Machine Learning · Computer Science 2026-05-19 Erchi Wang , Pengrun Huang , Eli Chien , Om Thakkar , Kamalika Chaudhuri , Yu-Xiang Wang , Ruihan Wu