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Large Language Models (LLMs) are often fine-tuned to adapt their general-purpose knowledge to specific tasks and domains such as cyber threat intelligence (CTI). Fine-tuning is mostly done through proprietary datasets that may contain…

Cryptography and Security · Computer Science 2026-03-13 Shashie Dilhara Batan Arachchige , Benjamin Zi Hao Zhao , Hassan Jameel Asghar , Dinusha Vatsalan , Dali Kaafar

Differential privacy is a promising privacy-preserving paradigm for statistical query processing over sensitive data. It works by injecting random noise into each query result, such that it is provably hard for the adversary to infer the…

Databases · Computer Science 2015-02-27 Ganzhao Yuan , Zhenjie Zhang , Marianne Winslett , Xiaokui Xiao , Yin Yang , Zhifeng Hao

Domain-adapted open-weight large language models (LLMs) offer promising healthcare applications, from queryable knowledge bases to multimodal assistants, with the crucial advantage of local deployment for privacy preservation. However,…

Computation and Language · Computer Science 2025-10-22 Lara Ahrens , Wilhelm Haverkamp , Nils Strodthoff

Large language models (LLMs) have emerged as important components across various fields, yet their training requires substantial computation resources and abundant labeled data. It poses a challenge to robustly training LLMs for individual…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-06-13 Jiaxing QI , Zhongzhi Luan , Shaohan Huang , Carol Fung , Hailong Yang , Depei Qian

Despite their strong linguistic capabilities, Large Language Models (LLMs) are computationally demanding and require substantial resources for fine-tuning, which is unadapted to privacy and budget constraints of many healthcare settings. To…

Computation and Language · Computer Science 2026-04-30 Pierre Epron , Adrien Coulet , Mehwish Alam

Recent advances in Retrieval-Augmented Generation (RAG) have enabled large language models (LLMs) to ground outputs in clinical evidence. However, connecting LLMs with external databases introduces the risk of contextual leakage: a subtle…

Computation and Language · Computer Science 2026-03-17 Shaowei Guan , Yu Zhai , Hin Chi Kwok , Jiawei Du , Xinyu Feng , Jing Li , Harry Qin , Vivian Hui

As Large Language Models (LLMs) proliferate, developing privacy safeguards for these models is crucial. One popular safeguard involves training LLMs in a differentially private manner. However, such solutions are shown to be computationally…

Machine Learning · Computer Science 2024-10-04 James Flemings , Meisam Razaviyayn , Murali Annavaram

Advancements in deep learning have generated a large-scale interest in the development of foundational deep learning models. The development of Large Language Models (LLM) has evolved as a transformative paradigm in conversational tasks,…

Computation and Language · Computer Science 2024-08-01 Nikil Sharan Prabahar Balasubramanian , Sagnik Dakshit

Large Language Models (LLMs) have emerged as dominant tools for various tasks, particularly when tailored for a specific target by prompt tuning. Nevertheless, concerns surrounding data privacy present obstacles due to the tuned prompts'…

Computation and Language · Computer Science 2024-03-19 Junyuan Hong , Jiachen T. Wang , Chenhui Zhang , Zhangheng Li , Bo Li , Zhangyang Wang

Large language models (LLMs) have demonstrated significant success in various domain-specific tasks, with their performance often improving substantially after fine-tuning. However, fine-tuning with real-world data introduces privacy risks.…

Cryptography and Security · Computer Science 2025-01-30 Atilla Akkus , Masoud Poorghaffar Aghdam , Mingjie Li , Junjie Chu , Michael Backes , Yang Zhang , Sinem Sav

Radiology report generation (RRG) models typically focus on individual exams, often overlooking the integration of historical visual or textual data, which is crucial for patient follow-ups. Traditional methods usually struggle with long…

Computer Vision and Pattern Recognition · Computer Science 2024-12-17 Tengfei Liu , Jiapu Wang , Yongli Hu , Mingjie Li , Junfei Yi , Xiaojun Chang , Junbin Gao , Baocai Yin

Large language models (LLMs) are becoming increasingly relevant as a potential tool for healthcare, aiding communication between clinicians, researchers, and patients. However, traditional evaluations of LLMs on medical exam questions do…

Computation and Language · Computer Science 2023-09-19 Rojin Ziaei , Samuel Schmidgall

Prompt privacy is crucial, especially when using online large language models (LLMs), due to the sensitive information often contained within prompts. While LLMs can enhance prompt privacy through text rewriting, existing methods primarily…

Computation and Language · Computer Science 2025-11-18 Mingchen Li , Heng Fan , Song Fu , Junhua Ding , Yunhe Feng

Evaluating generated radiology reports is crucial for the development of radiology AI, but existing metrics fail to reflect the task's clinical requirements. This study proposes a novel evaluation framework using large language models…

Computation and Language · Computer Science 2024-04-02 Zilong Wang , Xufang Luo , Xinyang Jiang , Dongsheng Li , Lili Qiu

Health monitoring systems have revolutionized modern healthcare by enabling the continuous capture of physiological and behavioral data, essential for preventive measures and early health intervention. While integrating this data with Large…

Machine Learning · Computer Science 2024-06-26 Ajan Subramanian , Zhongqi Yang , Iman Azimi , Amir M. Rahmani

Large language models (LLMs) have shown potential in biomedical applications, leading to efforts to fine-tune them on domain-specific data. However, the effectiveness of this approach remains unclear. This study evaluates the performance of…

Large Vision-Language Models (LVLMs) exhibit impressive potential across various tasks but also face significant privacy risks, limiting their practical applications. Current researches on privacy assessment for LVLMs is limited in scope,…

Cryptography and Security · Computer Science 2026-03-03 Jie Zhang , Xiangkui Cao , Zhouyu Han , Shiguang Shan , Xilin Chen

Natural Language Processing (NLP) techniques can be applied to help with the diagnosis of medical conditions such as depression, using a collection of a person's utterances. Depression is a serious medical illness that can have adverse…

Computation and Language · Computer Science 2022-06-17 Priyam Basu , Tiasa Singha Roy , Rakshit Naidu , Zumrut Muftuoglu , Sahib Singh , Fatemehsadat Mireshghallah

The shift towards efficient and automated data analysis through Machine Learning (ML) has notably impacted healthcare systems, particularly Radiomics. Radiomics leverages ML to analyze medical images accurately and efficiently for precision…

Cryptography and Security · Computer Science 2024-10-23 Kiarash Sedghighadikolaei , Attila A Yavuz

Users interacting with large language models (LLMs) under their real identifiers often unknowingly risk disclosing private information. Automatically notifying users whether their queries leak privacy and which phrases leak what private…

Computation and Language · Computer Science 2025-08-11 Hang Zeng , Xiangyu Liu , Yong Hu , Chaoyue Niu , Fan Wu , Shaojie Tang , Guihai Chen
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