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Despite rare diseases affecting 1 in 10 Americans, their differential diagnosis remains challenging. Due to their impressive recall abilities, large language models (LLMs) have been recently explored for differential diagnosis. Existing…

Artificial Intelligence · Computer Science 2026-01-21 Zilal Eiz AlDin , John Wu , Jeffrey Paul Fung , Jennifer King , Mya Watts , Lauren ONeill , Adam Richard Cross , Jimeng Sun

The recent success of large language models (LLMs) has paved the way for their adoption in the high-stakes domain of healthcare. Specifically, the application of LLMs in patient-trial matching, which involves assessing patient eligibility…

Artificial Intelligence · Computer Science 2023-12-18 Mauro Nievas , Aditya Basu , Yanshan Wang , Hrituraj Singh

Large language models (LLMs) such as ChatGPT have evolved into powerful and ubiquitous tools. Fine-tuning on small datasets allows LLMs to acquire specialized skills for specific tasks efficiently. Although LLMs provide great utility in…

Machine Learning · Computer Science 2025-10-08 Ruoxing Yang

Large Language Models (LLMs) have advanced various Natural Language Processing (NLP) tasks, such as text generation and translation, among others. However, these models often generate texts that can perpetuate biases. Existing approaches to…

Computation and Language · Computer Science 2025-01-07 Shaina Raza , Oluwanifemi Bamgbose , Shardul Ghuge , Fatemeh Tavakol , Deepak John Reji , Syed Raza Bashir

This study examines whether Low-Rank Adaptation (LoRA) fine-tuned Large Language Models (LLMs) can approximate the performance of fully fine-tuned models in generating human-interpretable decisions and explanations for malware…

Cryptography and Security · Computer Science 2025-11-26 Stephen C. Gravereaux , Sheikh Rabiul Islam

Modern distributed systems generate massive volumes of log data that are critical for detecting anomalies and cyber threats. However, in real world settings, these logs are often distributed across multiple organizations and cannot be…

Cryptography and Security · Computer Science 2026-04-22 Isaiah Thompson , Tanmay Sen , Ritwik Bhattacharya

Multimodal Large Language Models (LLMs) are pivotal in revolutionizing customer support and operations by integrating multiple modalities such as text, images, and audio. Federated Prompt Learning (FPL) is a recently proposed approach that…

Machine Learning · Computer Science 2025-02-14 Linh Tran , Wei Sun , Stacy Patterson , Ana Milanova

Large language models (LLMs) do not preserve privacy at inference-time. The LLM's outputs can inadvertently reveal information about the model's context, which presents a privacy challenge when the LLM is augmented via tools or databases…

Computation and Language · Computer Science 2026-02-03 Rushil Thareja , Preslav Nakov , Praneeth Vepakomma , Nils Lukas

The integration of large language models (LLMs) into automated algorithm design has shown promising potential. A prevalent approach embeds LLMs within search routines to iteratively generate and refine candidate algorithms. However, most…

Machine Learning · Computer Science 2026-05-20 Fei Liu , Rui Zhang , Xi Lin , Zhichao Lu , Qingfu Zhang

The proliferation of visual sensors in smart home environments, particularly through wearable devices like smart glasses, introduces profound privacy challenges. Existing privacy controls are often static and coarse-grained, failing to…

Human-Computer Interaction · Computer Science 2025-08-04 Shuning Zhang , Ying Ma , Xin Yi , Hewu Li

Automated labeling of chest X-ray reports is essential for enabling downstream tasks such as training image-based diagnostic models, population health studies, and clinical decision support. However, the high variability, complexity, and…

Computation and Language · Computer Science 2025-05-06 Brian Wong , Kaito Tanaka

At the heart of radiological practice is the challenge of integrating complex imaging data with clinical information to produce actionable insights. Nuanced application of language is key for various activities, including managing requests,…

Large Language Models (LLMs) embed sensitive, human-generated data, prompting the need for unlearning methods. Although certified unlearning offers strong privacy guarantees, its restrictive assumptions make it unsuitable for LLMs, giving…

Machine Learning · Computer Science 2025-06-03 Rongzhe Wei , Mufei Li , Mohsen Ghassemi , Eleonora Kreačić , Yifan Li , Xiang Yue , Bo Li , Vamsi K. Potluru , Pan Li , Eli Chien

Redacting Personally Identifiable Information (PII) from unstructured text is critical for ensuring data privacy in regulated domains. While earlier approaches have relied on rule-based systems and domain-specific Named Entity Recognition…

Cryptography and Security · Computer Science 2025-08-08 Leon Garza , Anantaa Kotal , Aritran Piplai , Lavanya Elluri , Prajit Das , Aman Chadha

While many online services provide privacy policies for end users to read and understand what personal data are being collected, these documents are often lengthy and complicated. As a result, the vast majority of users do not read them at…

Artificial Intelligence · Computer Science 2024-09-26 Bhanuka Silva , Dishanika Denipitiyage , Suranga Seneviratne , Anirban Mahanti , Aruna Seneviratne

Language modeling is a keystone task in natural language processing. When training a language model on sensitive information, differential privacy (DP) allows us to quantify the degree to which our private data is protected. However,…

Machine Learning · Computer Science 2020-10-27 Gavin Kerrigan , Dylan Slack , Jens Tuyls

Local differential privacy (LDP) has become a central topic in data privacy research, offering strong privacy guarantees by perturbing user data at the source and removing the need for a trusted curator. However, the noise introduced by LDP…

Machine Learning · Computer Science 2026-03-04 Caihong Qin , Yang Bai

The security of biomedical Multimodal Large Language Models (MLLMs) has attracted increasing attention. However, training samples easily contain private information and incorrect knowledge that are difficult to detect, potentially leading…

Computer Vision and Pattern Recognition · Computer Science 2025-08-07 Dunyuan Xu , Xikai Yang , Yaoqian Li , Jinpeng Li , Pheng-Ann Heng

Diffusion models (DMs) are one of the most widely used generative models for producing high quality images. However, a flurry of recent papers points out that DMs are least private forms of image generators, by extracting a significant…

Machine Learning · Statistics 2025-03-06 Michael F. Liu , Saiyue Lyu , Margarita Vinaroz , Mijung Park

Recent advancements in Large Multimodal Models (LMMs) have attracted interest in their generalization capability with only a few samples in the prompt. This progress is particularly relevant to the medical domain, where the quality and…

Computation and Language · Computer Science 2024-05-06 Seonhee Cho , Choonghan Kim , Jiho Lee , Chetan Chilkunda , Sujin Choi , Joo Heung Yoon
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