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Fourier ptychographic microscopy (FPM), characterized by high-throughput computational imaging, theoretically provides a cunning solution to the trade-off between spatial resolution and field of view (FOV), which has a promising prospect in…

Optics · Physics 2024-02-29 Shuhe Zhang , Aiye Wang , Jinghao Xu , Tianci Feng , Jinhua Zhou , An Pan

Super-resolution optical microscopy is a rapidly evolving scientific field dedicated to imaging sub-wavelength sized objects, leaving its mark in multiple branches of biology and technology. While several super-resolution optical microscopy…

Here we report nonlinear focal modulation microscopy (NFOMM) to achieve super-resolution imaging. Abandoning the previous persistence on minimizing the size of Gaussian emission pattern by directly narrowing (e.g. Minimizing the detection…

Fourier ptychographic microscopy enables gigapixel-scale imaging, with both large field-of-view and high resolution. Using a set of low-resolution images that are recorded under varying illumination angles, the goal is to computationally…

Signal Processing · Electrical Eng. & Systems 2018-03-13 Emrah Bostan , Mahdi Soltanolkotabi , David Ren , Laura Waller

Single-molecule fluorescence spectroscopy is a powerful method that avoids ensemble averaging, but its temporal resolution is limited by the fluorescence lifetime to nanoseconds at most. At the ensemble level, two-dimensional spectroscopy…

Optics · Physics 2024-10-11 Sanchayeeta Jana , Simon Durst , Markus Lippitz

Sub-micrometer scale light patterns play a pivotal role in various fields, including biology, biophysics, and AMO physics. High-resolution, in situ observation of light profiles is essential for their design and application. However,…

Till now the nanoscale focussing and imaging in the sub-diffraction limit is achieved mainly with the help of plasmonic field enhancement assisted with noble metal nanoparticles. Using far field imaging technique, we have recorded polarized…

Materials Science · Physics 2017-04-05 A. K. Sivadasan , Manas Sardar , Sandip Dhara

This article presents a method to perform diffraction tomography in a standard microscope that includes an LED array for illumination. After acquiring a sequence of intensity-only images of a thick sample, a ptychography-based…

Optics · Physics 2015-10-30 Roarke Horstmeyer , Changhuei Yang

Optical imaging plays a critical role in advancing our understanding of three dimensional dynamics of biological systems. Coherent imaging (CI) methods exploit spatial phase information, encoded through propagation of coherent signal light…

Optics · Physics 2015-07-24 Jeffrey J. Field , David G. Winters , Randy A. Bartels

Traditional phase-shifting interferometry technique cannot be used to measure time-varying phase distributions. But single shot techniques could resolve the problem. Many efforts have been made on the phase retrieval methods from a single…

Instrumentation and Detectors · Physics 2020-03-31 Lifa Hu , Wen Shena , Wenchao Ma , Dongting Hu , Xinyu Liu

Context. Remote sensing of weak and small-scale solar magnetic fields is of utmost relevance for a number of important open questions in solar physics. This requires the acquisition of spectropolarimetric data with high spatial resolution…

Instrumentation and Methods for Astrophysics · Physics 2016-05-18 F. A. Iglesias , A. Feller , K. Nagaraju , S. K. Solanki

We present a new interferometric imaging approach that allows for multiple-depth imaging in a single acquisition, using off-axis low-coherence holographic multiplexing. This technique enables sectioned imaging of multiple slices within a…

Optics · Physics 2019-03-29 Lauren Wolbromsky , Nir A. Turko , Natan T. Shaked

Real-time 3D fluorescence microscopy is crucial for the spatiotemporal analysis of live organisms, such as neural activity monitoring. The eXtended field-of-view light field microscope (XLFM), also known as Fourier light field microscope,…

Image and Video Processing · Electrical Eng. & Systems 2023-06-16 Josué Page Vizcaíno , Panagiotis Symvoulidis , Zeguan Wang , Jonas Jelten , Paolo Favaro , Edward S. Boyden , Tobias Lasser

The computational imaging technique of Fourier Ptychographic Microscopy (FPM) enables high-resolution imaging with a wide field of view and can serve as an extremely valuable tool, e.g. in the classification of cells in medical…

Image and Video Processing · Electrical Eng. & Systems 2025-08-25 Navya Sonal Agarwal , Jan Philipp Schneider , Kanchana Vaishnavi Gandikota , Syed Muhammad Kazim , John Meshreki , Ivo Ihrke , Michael Moeller

Fluorescence imaging is indispensable to biology and neuroscience. The need for large-scale imaging in freely behaving animals has further driven the development in miniaturized microscopes (miniscopes). However, conventional microscopes /…

Optics · Physics 2020-10-29 Yujia Xue , Ian G. Davison , David A. Boas , Lei Tian

Spectro-polarimetric imaging provides multidimensional optical information acquisition capabilities, offering significant potential for diverse applications. Current spectro-polarimetric imaging systems typically suffer from large physical…

Image and Video Processing · Electrical Eng. & Systems 2025-09-18 Jingyue Ma , Zhenming Yu , Zhengyang Li , Liang Lin , Liming Cheng , Jiayu Di , Tongshuo Zhang , Ning Zhan , Kun Xu

We report a computational 3D microscopy technique, termed Fourier ptychographic diffraction tomography (FPDT), that iteratively stitches together numerous variably illuminated, low-resolution images acquired with a low-numerical aperture…

Optics · Physics 2020-02-19 Chao Zuo , Jiasong Sun , Jiaji Li , Anand Asundi , Qian Chen

Fluorescence microscopy is an important and extensively utilised tool for imaging biological systems. However, the image resolution that can be obtained has a limit as defined through the laws of diffraction. Demand for improved resolution…

Biological Physics · Physics 2007-08-27 James H. Rice

Optical diffraction tomography is an indispensable tool for studying objects in three-dimensions due to its ability to accurately reconstruct scattering objects. Until now this technique has been limited to coherent light because spatial…

This paper considers a compressive multi-spectral light field camera model that utilizes a one-hot spectralcoded mask and a microlens array to capture spatial, angular, and spectral information using a single monochrome sensor. We propose a…

Computer Vision and Pattern Recognition · Computer Science 2025-03-18 Wen Cao , Ehsan Miandji , Jonas Unger