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Fluorescence lifetime imaging microscopy (FLIM) is a powerful quantitative technique that provides metabolic and molecular contrast, offering strong translational potential for label-free, real-time diagnostics. However, its clinical…

Computer Vision and Pattern Recognition · Computer Science 2025-12-19 Paloma Casteleiro Costa , Parnian Ghapandar Kashani , Xuhui Liu , Alexander Chen , Ary Portes , Julien Bec , Laura Marcu , Aydogan Ozcan

Modern Flash X-ray diffraction Imaging (FXI) acquires diffraction signals from single biomolecules at a high repetition rate from X-ray Free Electron Lasers (XFELs), easily obtaining millions of 2D diffraction patterns from a single…

Image and Video Processing · Electrical Eng. & Systems 2020-10-28 Jing Liu , Stefan Engblom , Carl Nettelblad

Mid-infrared photothermal microscopy is a new chemical imaging technology in which a visible beam senses the photothermal effect induced by a pulsed infrared laser. This technology provides infrared spectroscopic information at sub-micron…

Optics · Physics 2021-04-08 Yi Zhang , Haonan Zong , Cheng Zong , Yuying Tan , Meng Zhang , Yuewei Zhan , Ji-Xin Cheng

Fourier single-pixel imaging (FSI) is a data-efficient single-pixel imaging (SPI). However, there is still a serious challenge to obtain higher imaging quality using fewer measurements, which limits the development of real-time SPI. In this…

Image and Video Processing · Electrical Eng. & Systems 2023-11-07 Huan Cui , Jie Cao , Qun Hao , Haoyu Zhang , Chang Zhou

We report on the recently emerging (Laser) Light Sheet based Fluorescence Microscopy field (LSFM). The techniques used in this field allow to study and visualize biomedical objects non-destructively in high-resolution through virtual…

Instrumentation and Detectors · Physics 2011-06-17 Jan A. N. Buytaert , Emilie Descamps , Dominique Adriaens , Joris J. J. Dirckx

Multispectral imaging plays an important role in many applications from astronomical imaging, earth observation to biomedical imaging. However, the current technologies are complex with multiple alignment-sensitive components, predetermined…

Optics · Physics 2021-09-17 Sujit Kumar Sahoo , Dongliang Tang , Cuong Dang

Birefringence, an inherent characteristic of optically anisotropic materials, is widely utilized in various imaging applications ranging from material characterizations to clinical diagnosis. Polarized light microscopy enables…

Conventional imaging systems can only capture light intensity. Meanwhile, the lost phase information may be critical for a variety of applications such as label-free microscopy and optical metrology. Existing phase retrieval techniques…

A bright source of fiber-coupled, polarized single photons is an essential component of any realistic quantum network based on today's existing fiber infrastructure. Here, we develop a Purcell enhanced, polarized source of single photons at…

Quantum Physics · Physics 2022-03-04 Masakazu Sugawara , Yining Xuan , Yasuyoshi Mitsumori , Keiichi Edamatsu , Mark Sadgrove

PRISM (Polarized Radiation Imaging and Spectroscopy Mission) was proposed to ESA in response to the Call for White Papers for the definition of the L2 and L3 Missions in the ESA Science Programme. PRISM would have two instruments: (1) an…

Cosmology and Nongalactic Astrophysics · Physics 2015-07-29 PRISM Collaboration , Philippe Andre , Carlo Baccigalupi , Domingos Barbosa , James Bartlett , Nicola Bartolo , Elia Battistelli , Richard Battye , George Bendo , Jean-Philippe Bernard , Marco Bersanelli , Matthieu Bethermin , Pawel Bielewicz , Anna Bonaldi , Francois Bouchet , Francois Boulanger , Jan Brand , Martin Bucher , Carlo Burigana , Zhen-Yi Cai , Viviana Casasola , Guillaume Castex , Anthony Challinor , Jens Chluba , Sergio Colafrancesco , Francesco Cuttaia , Giuseppe D'Alessandro , Richard Davis , Miguel de Avillez , Paolo de Bernardis , Marco de Petris , Adriano de Rosa , Gianfranco de Zotti , Jacques Delabrouille , Clive Dickinson , Jose Maria Diego , Edith Falgarone , Pedro Ferreira , Katia Ferriere , Fabio Finelli , Andrew Fletcher , Gary Fuller , Silvia Galli , Ken Ganga , Juan Garcia-Bellido , Adnan Ghribi , Joaquin Gonzalez-Nuevo , Keith Grainge , Alessandro Gruppuso , Alex Hall , Carlos Hernandez-Monteagudo , Mark Jackson , Andrew Jaffe , Rishi Khatri , Luca Lamagna , Massimiliano Lattanzi , Paddy Leahy , Michele Liguori , Elisabetta Liuzzo , Marcos Lopez-Caniego , Juan Macias-Perez , Bruno Maffei , Davide Maino , Silvia Masi , Anna Mangilli , Marcella Massardi , Sabino Matarrese , Alessandro Melchiorri , Jean-Baptiste Melin , Aniello Mennella , Arturo Mignano , Marc-Antoine Miville-Deschenes , Federico Nati , Paolo Natoli , Mattia Negrello , Fabio Noviello , Francesco Paci , Rosita Paladino , Daniela Paoletti , Francesca Perrotta , Francesco Piacentini , Michel Piat , Lucio Piccirillo , Giampaolo Pisano , Gianluca Polenta , Sara Ricciardi , Matthieu Roman , Jose-Alberto Rubino-Martin , Maria Salatino , Alessandro Schillaci , Paul Shellard , Joseph Silk , Radek Stompor , Rashid Sunyaev , Andrea Tartari , Luca Terenzi , Luigi Toffolatti , Maurizio Tomasi , Tiziana Trombetti , Marco Tucci , Bartjan Van Tent , Licia Verde , Ben Wandelt , Stafford Withington

Photoluminesce (PL) spectroscopy offers excellent methods for mapping the PL decay on the nanosecond time scale. However, capturing maps of emission dynamics on the microsecond time scale can be highly time-consuming. We present a new…

Optics · Physics 2021-02-24 Jiri Junek , Karel Zidek

Plenoptic cameras offer a cost effective solution to capture light fields by multiplexing multiple views on a single image sensor. However, the high angular resolution is achieved at the expense of reducing the spatial resolution of each…

Computer Vision and Pattern Recognition · Computer Science 2018-09-28 Reuben A. Farrugia , C. Guillemot

We report the application of fifth order nonlinear optical processes for multiphoton microscopy, including fifth harmonic and 5-photon excitation fluorescence. This novel imaging modality has been characterized with spectral and power…

The realm of classical phase retrieval concerns itself with the arduous task of recovering a signal from its Fourier magnitude measurements, which are fraught with inherent ambiguities. A single-exposure intensity measurement is commonly…

Computer Vision and Pattern Recognition · Computer Science 2023-11-21 Yixiao Yang , Ran Tao , Kaixuan Wei , Jun Shi

This paper introduces a single-pixel HyperSpectral (HS) imaging framework based on Fourier Transform Interferometry (FTI). By combining a space-time coding of the light illumination with partial interferometric observations of a collimated…

Computer Vision and Pattern Recognition · Computer Science 2018-09-05 Amirafshar Moshtaghpour , José M. Bioucas-Dias , Laurent Jacques

The vectorial structure of light, amplitude, phase, and polarization, encodes essential information for applications ranging from super-resolution microscopy to high-capacity communications and quantum information processing. However,…

This thesis centres on the development of multidimensional fluorescence imaging tools, with a particular emphasis on fluorescence lifetime imaging (FLIM) microscopy for application to biological research. The key aspects of this thesis are…

Instrumentation and Detectors · Physics 2017-08-14 Egidijus Auksorius

Ptychography is a popular imaging technique that combines diffractive imaging with scanning microscopy. The technique consists of a coherent beam that is scanned across an object in a series of overlapping positions, leading to reliable and…

Numerical Analysis · Mathematics 2024-08-08 Ricardo Parada , Samy Wu Fung , Stanley Osher

We demonstrate Fourier single-pixel imaging in the terahertz regime. The experimental system is implemented with a photo-induced coded aperture setup, where a monolayer graphene on a high-resistance silicon substrate illuminated by a coded…

Applied Physics · Physics 2019-07-24 Rongbin She , Wenquan Liu , Yuanfu Lu , Zhisheng Zhou , Guangyuan Li
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