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Direct Image Classification from Fourier Ptychographic Microscopy Measurements without Reconstruction

Image and Video Processing 2025-08-25 v2 Artificial Intelligence Computer Vision and Pattern Recognition

Abstract

The computational imaging technique of Fourier Ptychographic Microscopy (FPM) enables high-resolution imaging with a wide field of view and can serve as an extremely valuable tool, e.g. in the classification of cells in medical applications. However, reconstructing a high-resolution image from tens or even hundreds of measurements is computationally expensive, particularly for a wide field of view. Therefore, in this paper, we investigate the idea of classifying the image content in the FPM measurements directly without performing a reconstruction step first. We show that Convolutional Neural Networks (CNN) can extract meaningful information from measurement sequences, significantly outperforming the classification on a single band-limited image (up to 12 %) while being significantly more efficient than a reconstruction of a high-resolution image. Furthermore, we demonstrate that a learned multiplexing of several raw measurements allows maintaining the classification accuracy while reducing the amount of data (and consequently also the acquisition time) significantly.

Keywords

Cite

@article{arxiv.2505.05054,
  title  = {Direct Image Classification from Fourier Ptychographic Microscopy Measurements without Reconstruction},
  author = {Navya Sonal Agarwal and Jan Philipp Schneider and Kanchana Vaishnavi Gandikota and Syed Muhammad Kazim and John Meshreki and Ivo Ihrke and Michael Moeller},
  journal= {arXiv preprint arXiv:2505.05054},
  year   = {2025}
}

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Presented in ISCS25

R2 v1 2026-06-28T23:25:28.932Z