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Interventional causal discovery seeks to identify causal relations by leveraging distributional changes introduced by interventions, even in the presence of latent confounders. Beyond the spurious dependencies induced by latent confounders,…

Machine Learning · Computer Science 2026-02-26 Gongxu Luo , Loka Li , Guangyi Chen , Haoyue Dai , Kun Zhang

Interpreting critical variables involved in complex biological processes related to survival time can help understand prediction from survival models, evaluate treatment efficacy, and develop new therapies for patients. Currently, the…

Machine Learning · Computer Science 2022-10-03 Xinxing Wu , Chong Peng , Richard Charnigo , Qiang Cheng

Rule-based models, e.g., decision trees, are widely used in scenarios demanding high model interpretability for their transparent inner structures and good model expressivity. However, rule-based models are hard to optimize, especially on…

Machine Learning · Computer Science 2024-01-31 Zhuo Wang , Wei Zhang , Ning Liu , Jianyong Wang

Neural network architectures have been extensively employed in the fair representation learning setting, where the objective is to learn a new representation for a given vector which is independent of sensitive information. Various…

Machine Learning · Computer Science 2022-02-08 Mattia Cerrato , Alesia Vallenas Coronel , Marius Köppel , Alexander Segner , Roberto Esposito , Stefan Kramer

The recent advances in single-cell technologies have enabled us to profile genomic features at unprecedented resolution and datasets from multiple domains are available, including datasets that profile different types of genomic features…

Machine Learning · Statistics 2020-06-09 Pengcheng Zeng , Zhixiang Lin

Parametric system identification methods estimate the parameters of explicitly defined physical systems from data. Yet, they remain constrained by the need to provide an explicit function space, typically through a predefined library of…

Machine Learning · Computer Science 2026-03-17 Markus W. Baumgartner , Anson Lei , Joe Watson , Ingmar Posner

As a key component to intuitive cognition and reasoning solutions in human intelligence, causal knowledge provides great potential for reinforcement learning (RL) agents' interpretability towards decision-making by helping reduce the…

Machine Learning · Computer Science 2025-04-25 Ruichu Cai , Siyang Huang , Jie Qiao , Wei Chen , Yan Zeng , Keli Zhang , Fuchun Sun , Yang Yu , Zhifeng Hao

Contrastive learning (CL) methods effectively learn data representations in a self-supervision manner, where the encoder contrasts each positive sample over multiple negative samples via a one-vs-many softmax cross-entropy loss. By…

Machine Learning · Computer Science 2023-08-16 Huangjie Zheng , Xu Chen , Jiangchao Yao , Hongxia Yang , Chunyuan Li , Ya Zhang , Hao Zhang , Ivor Tsang , Jingren Zhou , Mingyuan Zhou

It is evidence that representation learning can improve model's performance over multiple downstream tasks in many real-world scenarios, such as image classification and recommender systems. Existing learning approaches rely on establishing…

Machine Learning · Computer Science 2022-02-18 Mengyue Yang , Xinyu Cai , Furui Liu , Xu Chen , Zhitang Chen , Jianye Hao , Jun Wang

Designing a network to learn a molecule structure given its physical/chemical properties is a hard problem, but is useful for drug discovery tasks. In this paper, we incorporate higher-order relational learning of Factor Graphs with strong…

Machine Learning · Computer Science 2020-12-11 Hieu Le Trung , Yiqing Xu , Wee Sun Lee

Latent variable models such as the Variational Auto-Encoder (VAE) have become a go-to tool for analyzing biological data, especially in the field of single-cell genomics. One remaining challenge is the interpretability of latent variables…

Genomics · Quantitative Biology 2023-02-20 Romain Lopez , Nataša Tagasovska , Stephen Ra , Kyunghyn Cho , Jonathan K. Pritchard , Aviv Regev

Estimating treatment effects from observational data is challenging due to two main reasons: (a) hidden confounding, and (b) covariate mismatch (control and treatment groups not having identical distributions). Long lines of works exist…

Machine Learning · Computer Science 2025-04-30 Praharsh Nanavati , Ranjitha Prasad , Karthikeyan Shanmugam

A key question in causal inference analyses is how to find subgroups with elevated treatment effects. This paper takes a machine learning approach and introduces a generative model, Causal Rule Sets (CRS), for interpretable subgroup…

Artificial Intelligence · Computer Science 2021-05-21 Tong Wang , Cynthia Rudin

Meta-learning enables rapid generalization to new tasks by learning knowledge from various tasks. It is intuitively assumed that as the training progresses, a model will acquire richer knowledge, leading to better generalization…

Machine Learning · Computer Science 2024-05-30 Jingyao Wang , Yi Ren , Zeen Song , Jianqi Zhang , Changwen Zheng , Wenwen Qiang

We consider the linear causal representation learning setting where we observe a linear mixing of $d$ unknown latent factors, which follow a linear structural causal model. Recent work has shown that it is possible to recover the latent…

Machine Learning · Computer Science 2024-11-05 Tianyu Chen , Kevin Bello , Francesco Locatello , Bryon Aragam , Pradeep Ravikumar

Reinforcement learning (RL) can be formulated as a sequence modeling problem, where models predict future actions based on historical state-action-reward sequences. Current approaches typically require long trajectory sequences to model the…

Machine Learning · Computer Science 2024-12-23 Hemant Kumawat , Saibal Mukhopadhyay

A major open problem on the road to artificial intelligence is the development of incrementally learning systems that learn about more and more concepts over time from a stream of data. In this work, we introduce a new training strategy,…

Computer Vision and Pattern Recognition · Computer Science 2017-04-17 Sylvestre-Alvise Rebuffi , Alexander Kolesnikov , Georg Sperl , Christoph H. Lampert

Learning a causal directed acyclic graph from data is a challenging task that involves solving a combinatorial problem for which the solution is not always identifiable. A new line of work reformulates this problem as a continuous…

Machine Learning · Computer Science 2020-11-05 Philippe Brouillard , Sébastien Lachapelle , Alexandre Lacoste , Simon Lacoste-Julien , Alexandre Drouin

In this paper, we discuss structure learning of causal networks from multiple data sets obtained by external intervention experiments where we do not know what variables are manipulated. For example, the conditions in these experiments are…

Machine Learning · Statistics 2016-10-28 Yango He , Zhi Geng

Large-scale networked systems, such as traffic, power, and wireless grids, challenge reinforcement-learning agents with both scale and environment shifts. To address these challenges, we propose GSAC (Generalizable and Scalable…

Machine Learning · Computer Science 2025-10-27 Hao Liang , Shuqing Shi , Yudi Zhang , Biwei Huang , Yali Du