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Self-supervised representation learning has achieved remarkable success in recent years. By subverting the need for supervised labels, such approaches are able to utilize the numerous unlabeled images that exist on the Internet and in…

Computer Vision and Pattern Recognition · Computer Science 2021-09-01 Yilun Du , Chuang Gan , Phillip Isola

Prevalent in biomedical applications (e.g., human phenotype research), multimodal datasets can provide valuable insights into the underlying physiological mechanisms. However, current machine learning (ML) models designed to analyze these…

Interpretable policy learning seeks to estimate intelligible decision policies from observed actions; however, existing models force a tradeoff between accuracy and interpretability, limiting data-driven interpretations of human…

Machine Learning · Computer Science 2024-05-09 Jannik Deuschel , Caleb N. Ellington , Yingtao Luo , Benjamin J. Lengerich , Pascal Friederich , Eric P. Xing

Deep Generative Models (DGMs) are versatile tools for learning data representations while adequately incorporating domain knowledge such as the specification of conditional probability distributions. Recently proposed DGMs tackle the…

Machine Learning · Computer Science 2024-01-30 Romain Lopez , Jan-Christian Huetter , Ehsan Hajiramezanali , Jonathan Pritchard , Aviv Regev

Estimating individual-level treatment effect from observational data is a fundamental problem in causal inference and has attracted increasing attention in the fields of education, healthcare, and public policy.In this work, we concentrate…

Machine Learning · Computer Science 2025-07-10 Hui Meng , Keping Yang , Xuyu Peng , Bo Zheng

Understanding causal relationships between variables is fundamental across scientific disciplines. Most causal discovery algorithms rely on two key assumptions: (i) all variables are observed, and (ii) the underlying causal graph is…

Machine Learning · Computer Science 2026-01-26 Muralikrishnna G. Sethuraman , Faramarz Fekri

Learning causal representations from observational and interventional data in the absence of known ground-truth graph structures necessitates implicit latent causal representation learning. Implicit learning of causal mechanisms typically…

Machine Learning · Computer Science 2024-08-19 Shayan Shirahmad Gale Bagi , Zahra Gharaee , Oliver Schulte , Mark Crowley

Visual representation learning is ubiquitous in various real-world applications, including visual comprehension, video understanding, multi-modal analysis, human-computer interaction, and urban computing. Due to the emergence of huge…

Computer Vision and Pattern Recognition · Computer Science 2023-03-23 Yang Liu , Yushen Wei , Hong Yan , Guanbin Li , Liang Lin

Recent advances in computer vision and robotics enabled automated large-scale biological image analysis. Various machine learning approaches have been successfully applied to phenotypic profiling. However, it remains unclear how they…

Image and Video Processing · Electrical Eng. & Systems 2022-03-09 Andrei Dmitrenko , Mauro M. Masiero , Nicola Zamboni

Learning disentangled representations from visual data, where different high-level generative factors are independently encoded, is of importance for many computer vision tasks. Solving this problem, however, typically requires to…

Computer Vision and Pattern Recognition · Computer Science 2019-01-25 Adria Ruiz , Oriol Martinez , Xavier Binefa , Jakob Verbeek

This paper studies the causal representation learning problem when the latent causal variables are observed indirectly through an unknown linear transformation. The objectives are: (i) recovering the unknown linear transformation (up to…

Machine Learning · Statistics 2023-05-02 Burak Varici , Emre Acarturk , Karthikeyan Shanmugam , Abhishek Kumar , Ali Tajer

Causal reasoning and discovery, two fundamental tasks of causal analysis, often face challenges in applications due to the complexity, noisiness, and high-dimensionality of real-world data. Despite recent progress in identifying latent…

Machine Learning · Computer Science 2025-11-18 Dingling Yao , Shimeng Huang , Riccardo Cadei , Kun Zhang , Francesco Locatello

Causal discovery from data affected by latent confounders is an important and difficult challenge. Causal functional model-based approaches have not been used to present variables whose relationships are affected by latent confounders,…

Machine Learning · Computer Science 2020-11-05 Takashi Nicholas Maeda , Shohei Shimizu

Representation learning assumes that real-world data is generated by a few semantically meaningful generative factors (i.e., sources of variation) and aims to discover them in the latent space. These factors are expected to be causally…

Machine Learning · Computer Science 2023-10-27 Xiaoyu Liu , Jiaxin Yuan , Bang An , Yuancheng Xu , Yifan Yang , Furong Huang

Extracting a stable and compact representation of the environment is crucial for efficient reinforcement learning in high-dimensional, noisy, and non-stationary environments. Different categories of information coexist in such environments…

Machine Learning · Computer Science 2023-06-28 Yu-Ren Liu , Biwei Huang , Zhengmao Zhu , Honglong Tian , Mingming Gong , Yang Yu , Kun Zhang

Domain adaptation solves the learning problem in a target domain by leveraging the knowledge in a relevant source domain. While remarkable advances have been made, almost all existing domain adaptation methods heavily require large amounts…

Machine Learning · Computer Science 2021-10-13 Shuai Yang , Kui Yu , Fuyuan Cao , Lin Liu , Hao Wang , Jiuyong Li

Due to cancer's complex nature and variable response to therapy, precision oncology informed by omics sequence analysis has become the current standard of care. However, the amount of data produced for each patients makes it difficult to…

Machine Learning · Computer Science 2023-10-30 Patrick J. Lawrence , Xia Ning

Perturbation screens hold the potential to systematically map regulatory processes at single-cell resolution, yet modeling and predicting transcriptome-wide responses to perturbations remains a major computational challenge. Existing…

Molecular Networks · Quantitative Biology 2026-01-26 Lars Lorch , Jiaqi Zhang , Charlotte Bunne , Andreas Krause , Bernhard Schölkopf , Caroline Uhler

Citation-based Information Retrieval (IR) methods for scientific documents have proven effective for IR applications, such as Plagiarism Detection or Literature Recommender Systems in academic disciplines that use many references. In…

Information Retrieval · Computer Science 2023-03-21 Philipp Scharpf , Moritz Schubotz , Howard S. Cohl , Corinna Breitinger , Bela Gipp

Identifying causal parameters from observational data is fraught with subtleties due to the issues of selection bias and confounding. In addition, more complex questions of interest, such as effects of treatment on the treated and mediated…

Methodology · Statistics 2015-11-17 Ilya Shpitser , Eric Tchetgen Tchetgen