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Identifying the causal variables of an environment and how to intervene on them is of core value in applications such as robotics and embodied AI. While an agent can commonly interact with the environment and may implicitly perturb the…

Machine Learning · Computer Science 2023-06-19 Phillip Lippe , Sara Magliacane , Sindy Löwe , Yuki M. Asano , Taco Cohen , Efstratios Gavves

Causal learning is a beneficial approach to analyze the cause and effect relationships among variables in a dataset. A causal graph can be generated from a dataset using a particular causal algorithm, for instance, the PC algorithm or Fast…

Machine Learning · Computer Science 2019-10-09 Teny Handhayani , James Cussens

Alterations in the geometry and function of the heart define well-established causes of cardiovascular disease. However, current approaches to the diagnosis of cardiovascular diseases often rely on subjective human assessment as well as…

Computer Vision and Pattern Recognition · Computer Science 2018-07-19 Carlo Biffi , Ozan Oktay , Giacomo Tarroni , Wenjia Bai , Antonio De Marvao , Georgia Doumou , Martin Rajchl , Reem Bedair , Sanjay Prasad , Stuart Cook , Declan O'Regan , Daniel Rueckert

A key goal of computational personalized medicine is to systematically utilize genomic and other molecular features of samples to predict drug responses for a previously unseen sample. Such predictions are valuable for developing hypotheses…

In real-world federated learning scenarios, participants could have their own personalized labels which are incompatible with those from other clients, due to using different label permutations or tackling completely different tasks or…

Machine Learning · Computer Science 2022-02-02 Wonyong Jeong , Sung Ju Hwang

Causal structure learning refers to a process of identifying causal structures from observational data, and it can have multiple applications in biomedicine and health care. This paper provides a practical review and tutorial on scalable…

Machine Learning · Computer Science 2023-01-20 Pulakesh Upadhyaya , Kai Zhang , Can Li , Xiaoqian Jiang , Yejin Kim

This paper proposes a Disentangled gEnerative cAusal Representation (DEAR) learning method under appropriate supervised information. Unlike existing disentanglement methods that enforce independence of the latent variables, we consider the…

Machine Learning · Computer Science 2022-10-04 Xinwei Shen , Furui Liu , Hanze Dong , Qing Lian , Zhitang Chen , Tong Zhang

Identifying latent variables and causal structures from observational data is essential to many real-world applications involving biological data, medical data, and unstructured data such as images and languages. However, this task can be…

Machine Learning · Computer Science 2023-11-01 Lingjing Kong , Biwei Huang , Feng Xie , Eric Xing , Yuejie Chi , Kun Zhang

Personalized learner modeling using cognitive diagnosis (CD), which aims to model learners' cognitive states by diagnosing learner traits from behavioral data, is a fundamental yet significant task in many web learning services. Existing…

Artificial Intelligence · Computer Science 2024-02-20 Jiatong Li , Qi Liu , Fei Wang , Jiayu Liu , Zhenya Huang , Fangzhou Yao , Linbo Zhu , Yu Su

Causal inference is capable of estimating the treatment effect (i.e., the causal effect of treatment on the outcome) to benefit the decision making in various domains. One fundamental challenge in this research is that the treatment…

Machine Learning · Computer Science 2021-12-28 Qian Li , Zhichao Wang , Shaowu Liu , Gang Li , Guandong Xu

This paper proposes an efficient approach to learning disentangled representations with causal mechanisms based on the difference of conditional probabilities in original and new distributions. We approximate the difference with models'…

Machine Learning · Computer Science 2024-01-03 Yuanpeng Li , Joel Hestness , Mohamed Elhoseiny , Liang Zhao , Kenneth Church

Deep learning methods are highly accurate, yet their opaque decision process prevents them from earning full human trust. Concept-based models aim to address this issue by learning tasks based on a set of human-understandable concepts.…

Conventional representation learning methods learn a universal representation that primarily captures dominant semantics, which may not always align with customized downstream tasks. For instance, in animal habitat analysis, researchers…

Computer Vision and Pattern Recognition · Computer Science 2025-12-16 Honglin Liu , Chao Sun , Peng Hu , Yunfan Li , Xi Peng

Unsupervised learning enables modeling complex images without the need for annotations. The representation learned by such models can facilitate any subsequent analysis of large image datasets. However, some generative factors that cause…

Image and Video Processing · Electrical Eng. & Systems 2020-08-27 Maxime W. Lafarge , Josien P. W. Pluim , Mitko Veta

Undertaking causal inference with observational data is incredibly useful across a wide range of tasks including the development of medical treatments, advertisements and marketing, and policy making. There are two significant challenges…

Machine Learning · Statistics 2022-01-19 Matthew James Vowels , Necati Cihan Camgoz , Richard Bowden

Phenotype-based screening has attracted much attention for identifying cell-active compounds. Transcriptional and proteomic profiles of cell population or single cells are informative phenotypic measures of cellular responses to…

Quantitative Methods · Quantitative Biology 2023-11-20 Wei Huang , Aichun Zhu , Hui Liu

Single-cell RNA sequencing (scRNA-seq) data is a potent tool for comprehending the "language of life" and can provide insights into various downstream biomedical tasks. Large-scale language models (LLMs) are starting to be used for cell…

Computational Engineering, Finance, and Science · Computer Science 2023-06-08 Suyuan Zhao , Jiahuan Zhang , Zaiqing Nie

A central question in human immunology is how a patient's repertoire of T cells impacts disease. Here, we introduce a method to infer the causal effects of T cell receptor (TCR) sequences on patient outcomes using observational TCR…

Machine Learning · Statistics 2024-10-21 Eli N. Weinstein , Elizabeth B. Wood , David M. Blei

Deep Reinforcement Learning (DRL) methods have performed well in an increasing numbering of high-dimensional visual decision making domains. Among all such visual decision making problems, those with discrete action spaces often tend to…

Machine Learning · Computer Science 2017-05-23 Sahil Sharma , Aravind Suresh , Rahul Ramesh , Balaraman Ravindran

Functional magnetic resonance imaging (fMRI) is widely used for studying and diagnosing brain disorders, with functional connectivity (FC) matrices providing powerful representations of large-scale neural interactions. However, existing…

Tissues and Organs · Quantitative Biology 2026-04-17 Qianyu Chen , Shujian Yu