Related papers: Training-free CryoET Tomogram Segmentation
This study presents a novel multimodal medical image zero-shot segmentation algorithm named the text-visual-prompt segment anything model (TV-SAM) without any manual annotations. The TV-SAM incorporates and integrates the large language…
We propose a framework to jointly determine the deformation parameters and reconstruct the unknown volume in electron cryotomography (CryoET). CryoET aims to reconstruct three-dimensional biological samples from two-dimensional projections.…
Assessment of the glomerular basement membrane (GBM) in transmission electron microscopy (TEM) is crucial for diagnosing chronic kidney disease (CKD). The lack of domain-independent automatic segmentation tools for the GBM necessitates an…
Cryogenic electron microscopy (cryo-EM) provides images from different copies of the same biomolecule in arbitrary orientations. Here, we present an end-to-end unsupervised approach that learns individual particle orientations from cryo-EM…
Cryo-electron microscopy (cryo-EM) has revolutionized structural biology by enabling near-atomic-level visualization of biomolecular assemblies. However, the exponential growth in cryo-EM data throughput and complexity, coupled with diverse…
Cryo-electron tomography (cryo-ET) has emerged as a powerful technique for imaging macromolecular complexes in their near-native states. However, the localization of 3D particles in cellular environments still presents a significant…
Nucleus segmentation is an important analysis task in digital pathology. However, methods for automatic segmentation often struggle with new data from a different distribution, requiring users to manually annotate nuclei and retrain…
Present-day deep neural networks for video semantic segmentation require a large number of fine-grained pixel-level annotations to achieve the best possible results. Obtaining such annotations, however, is very expensive. On the other hand,…
Cellular Electron Cryo-Tomography (CECT) is a powerful 3D imaging tool for studying the native structure and organization of macromolecules inside single cells. For systematic recognition and recovery of macromolecular structures captured…
The Segment Anything Model (SAM) enables promptable, high-quality segmentation but is often too computationally expensive for latency-critical settings. TinySAM is a lightweight, distilled SAM variant that preserves strong zero-shot mask…
Medical image segmentation is vital for clinical diagnosis, yet current deep learning methods often demand extensive expert effort, i.e., either through annotating large training datasets or providing prompts at inference time for each new…
The recently released Segment Anything Model (SAM) has shown powerful zero-shot segmentation capabilities through a semi-automatic annotation setup in which the user can provide a prompt in the form of clicks or bounding boxes. There is…
Electron tomography (ET) allows high-resolution reconstructions of macromolecular complexes at nearnative state. Cellular structures segmentation in the reconstruction data from electron tomographic images is often required for analyzing…
The three-dimensional structure of proteins plays a crucial role in determining their function. Protein structure prediction methods, like AlphaFold, offer rapid access to a protein structure. However, large protein complexes cannot be…
Brain tumor segmentation is important for diagnosis of the tumor, and current deep-learning methods rely on a large set of annotated images for training, with high annotation costs. Unsupervised segmentation is promising to avoid human…
Segment Anything Model (SAM), a prompt-driven foundation model for natural image segmentation, has demonstrated impressive zero-shot performance. However, SAM does not work when directly applied to medical image segmentation, since SAM…
Cryo-ET allows to generate tomograms of biological samples in situ, capturing complex structures in their native context. Despite low signal-to-noise ratio in reconstructed volumes, the large number of copies of the same macromolecules…
Whole-body PET/CT is a cornerstone of oncological imaging, yet accurate lesion segmentation remains challenging due to tracer heterogeneity, physiological uptake, and multi-center variability. While fully automated methods have advanced…
Segmentation is vital for ophthalmology image analysis. But its various modal images hinder most of the existing segmentation algorithms applications, as they rely on training based on a large number of labels or hold weak generalization…
Advances in machine learning, especially the introduction of transformer architectures and vision transformers, have led to the development of highly capable computer vision foundation models. The segment anything model (known colloquially…