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Accurate segmentation of critical anatomical structures is at the core of medical image analysis. The main bottleneck lies in gathering the requisite expert-labeled image annotations in a scalable manner. Methods that permit to produce…

Computer Vision and Pattern Recognition · Computer Science 2020-07-09 Yuhang Lu , Weijian Li , Kang Zheng , Yirui Wang , Adam P. Harrison , Chihung Lin , Song Wang , Jing Xiao , Le Lu , Chang-Fu Kuo , Shun Miao

In cryo-electron microscopy, accurate particle localization and classification are imperative. Recent deep learning solutions, though successful, require extensive training data sets. The protracted generation time of physics-based models,…

Machine Learning · Computer Science 2025-02-20 Pavol Harar , Lukas Herrmann , Philipp Grohs , David Haselbach

Semantic segmentation of microscopic cell images using deep learning is an important technique, however, it requires a large number of images and ground truth labels for training. To address the above problem, we consider an efficient…

Computer Vision and Pattern Recognition · Computer Science 2023-04-18 Sota Kato , Kazuhiro Hotta

The Segment Anything Model (SAM) and CLIP are remarkable vision foundation models (VFMs). SAM, a prompt driven segmentation model, excels in segmentation tasks across diverse domains, while CLIP is renowned for its zero shot recognition…

Computer Vision and Pattern Recognition · Computer Science 2024-05-01 Sidra Aleem , Fangyijie Wang , Mayug Maniparambil , Eric Arazo , Julia Dietlmeier , Guenole Silvestre , Kathleen Curran , Noel E. O'Connor , Suzanne Little

Medical image segmentation is a key task in the imaging workflow, influencing many image-based decisions. Traditional, fully-supervised segmentation models rely on large amounts of labeled training data, typically obtained through manual…

Image and Video Processing · Electrical Eng. & Systems 2025-11-04 Tyler Ward , Meredith K. Owen , O'Kira Coleman , Brian Noehren , Abdullah-Al-Zubaer Imran

Accurate vessel segmentation is critical for clinical applications such as disease diagnosis and surgical planning, yet remains challenging due to thin, branching structures and low texture contrast. While foundation models like the Segment…

Computer Vision and Pattern Recognition · Computer Science 2025-12-17 Suzhong Fu , Rui Sun , Xuan Ding , Jingqi Dong , Yiming Yang , Yao Zhu , Min Chang Jordan Ren , Delin Deng , Angelica Aviles-Rivero , Shuguang Cui , Zhen Li

Histopathology nuclei segmentation is crucial for quantitative tissue analysis and cancer diagnosis. Although existing segmentation methods have achieved strong performance, they are often computationally heavy and show limited…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Muhammad Hassan Maqsood , Yanming Zhu , Alfred Lam , Getamesay Dagnaw , Xuefei Yin , Alan Wee-Chung Liew

Cryo-electron microscopy (cryo-EM) is a powerful imaging technique for reconstructing three-dimensional molecular structures from noisy tomographic projection images of randomly oriented particles. We introduce a new data fusion framework,…

Computer Vision and Pattern Recognition · Computer Science 2025-12-15 Joe Kileel , Oscar Mickelin , Amit Singer , Sheng Xu

Widely adopted medical image segmentation methods, although efficient, are primarily deterministic and remain poorly amenable to natural language prompts. Thus, they lack the capability to estimate multiple proposals, human interaction, and…

Computer Vision and Pattern Recognition · Computer Science 2026-01-23 Yuan Lin , Murong Xu , Marc Hölle , Chinmay Prabhakar , Andreas Maier , Vasileios Belagiannis , Bjoern Menze , Suprosanna Shit

Accurate segmentation of cardiac structures in cardiovascular magnetic resonance (CMR) images is essential for reliable diagnosis and treatment of cardiovascular diseases. However, manual segmentation remains time-consuming and suffers from…

Computer Vision and Pattern Recognition · Computer Science 2026-04-07 Ujjwal Jain

This paper provides insights on the effectiveness of the zero shot, prompt-based Segment Anything Model (SAM) and its updated versions, SAM 2 and SAM 2.1, along with the non-promptable conventional neural network (CNN), for segmenting solar…

Computer Vision and Pattern Recognition · Computer Science 2025-01-06 Osher Rafaeli , Tal Svoray , Roni Blushtein-Livnon , Ariel Nahlieli

Obtaining large-scale medical data, annotated or unannotated, is challenging due to stringent privacy regulations and data protection policies. In addition, annotating medical images requires that domain experts manually delineate…

Computer Vision and Pattern Recognition · Computer Science 2025-05-16 Tushar Kataria , Shireen Y. Elhabian

The Segment Anything Model (SAM) is a deep neural network foundational model designed to perform instance segmentation which has gained significant popularity given its zero-shot segmentation ability. SAM operates by generating masks based…

Computer Vision and Pattern Recognition · Computer Science 2024-04-19 Yona Falinie A. Gaus , Neelanjan Bhowmik , Brian K. S. Isaac-Medina , Toby P. Breckon

The Segment-Anything Model (SAM) is a vision foundation model for segmentation with a prompt-driven framework. SAM generates class-agnostic masks based on user-specified instance-referring prompts. However, adapting SAM for automated…

Computer Vision and Pattern Recognition · Computer Science 2024-11-22 Hussni Mohd Zakir , Eric Tatt Wei Ho

Although the Segment Anything Model (SAM) is highly effective in natural image segmentation, it requires dependencies on prompts, which limits its applicability to medical imaging where manual prompts are often unavailable. Existing efforts…

Computer Vision and Pattern Recognition · Computer Science 2025-06-04 Mengmeng Zhang , Xingyuan Dai , Yicheng Sun , Jing Wang , Yueyang Yao , Xiaoyan Gong , Fuze Cong , Feiyue Wang , Yisheng Lv

Is Segment Anything Model 3 (SAM3) capable in segmenting Any Pathology Images? Digital pathology segmentation spans tissue-level and nuclei-level scales, where traditional methods often suffer from high annotation costs and poor…

Computer Vision and Pattern Recognition · Computer Science 2026-05-20 Qiuyu Kong , Shakiba Sharifi , Yiming Wang , Marco Cristani , Zanxi Ruan

Automatic segmentation of medical images is crucial in modern clinical workflows. The Segment Anything Model (SAM) has emerged as a versatile tool for image segmentation without specific domain training, but it requires human prompts and…

Computer Vision and Pattern Recognition · Computer Science 2024-05-16 Yunxiang Li , Bowen Jing , Zihan Li , Jing Wang , You Zhang

Deep learning-based medical image segmentation typically requires large amount of labeled data for training, making it less applicable in clinical settings due to high annotation cost. Semi-supervised learning (SSL) has emerged as an…

Image and Video Processing · Electrical Eng. & Systems 2025-03-03 Yichi Zhang , Bohao Lv , Le Xue , Wenbo Zhang , Yuchen Liu , Yu Fu , Yuan Cheng , Yuan Qi

Segmenting objects with complex shapes, such as wires, bicycles, or structural grids, remains a significant challenge for current segmentation models, including the Segment Anything Model (SAM) and its high-quality variant SAM-HQ. These…

Computer Vision and Pattern Recognition · Computer Science 2025-06-09 Luka Vetoshkin , Dmitry Yudin

Accurate segmentation for medical images is important for clinical diagnosis. Existing automatic segmentation methods are mainly based on fully supervised learning and have an extremely high demand for precise annotations, which are very…

Computer Vision and Pattern Recognition · Computer Science 2021-06-10 Yuanpeng Liu , Qinglei Hui , Zhiyi Peng , Shaolin Gong , Dexing Kong
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