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Related papers: Training-free CryoET Tomogram Segmentation

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Motivation: Cellular Electron CryoTomography (CECT) enables 3D visualization of cellular organization at near-native state and in sub-molecular resolution, making it a powerful tool for analyzing structures of macromolecular complexes and…

Quantitative Methods · Quantitative Biology 2017-04-14 Min Xu , Xiaoqi Chai , Hariank Muthakana , Xiaodan Liang , Ge Yang , Tzviya Zeev-Ben-Mordehai , Eric Xing

The Segment Anything Model (SAM) is a recently proposed prompt-based segmentation model in a generic zero-shot segmentation approach. With the zero-shot segmentation capacity, SAM achieved impressive flexibility and precision on various…

Computer Vision and Pattern Recognition · Computer Science 2023-08-30 Can Cui , Ruining Deng , Quan Liu , Tianyuan Yao , Shunxing Bao , Lucas W. Remedios , Yucheng Tang , Yuankai Huo

Cryo-electron microscopy (cryo-EM) studies using single particle reconstruction is extensively used to reveal structural information of macromolecular complexes. Aiming at the highest achievable resolution, state of the art electron…

Computer Vision and Pattern Recognition · Computer Science 2020-05-04 Ramin Norousi , Stephan Wickles , Thomas Becker , Roland Beckmann , Volker J. Schmid , Achim Tresch

The Segment Anything Model (SAM) is a powerful foundation model that has revolutionised image segmentation. To apply SAM to surgical instrument segmentation, a common approach is to locate precise points or boxes of instruments and then use…

Computer Vision and Pattern Recognition · Computer Science 2023-12-22 Wenxi Yue , Jing Zhang , Kun Hu , Yong Xia , Jiebo Luo , Zhiyong Wang

Segmentation is a fundamental problem in surgical scene analysis using artificial intelligence. However, the inherent data scarcity in this domain makes it challenging to adapt traditional segmentation techniques for this task. To tackle…

Computer Vision and Pattern Recognition · Computer Science 2023-08-08 Jay N. Paranjape , Nithin Gopalakrishnan Nair , Shameema Sikder , S. Swaroop Vedula , Vishal M. Patel

Cryo-electron microscopy (cryo-EM) has become a tool of fundamental importance in structural biology, helping us understand the basic building blocks of life. The algorithmic challenge of cryo-EM is to jointly estimate the unknown 3D poses…

Computer Vision and Pattern Recognition · Computer Science 2022-09-01 Axel Levy , Frédéric Poitevin , Julien Martel , Youssef Nashed , Ariana Peck , Nina Miolane , Daniel Ratner , Mike Dunne , Gordon Wetzstein

Image segmentation is usually addressed by training a model for a fixed set of object classes. Incorporating additional classes or more complex queries later is expensive as it requires re-training the model on a dataset that encompasses…

Computer Vision and Pattern Recognition · Computer Science 2022-03-31 Timo Lüddecke , Alexander S. Ecker

Accurate organ segmentation is essential for clinical tasks such as radiotherapy planning and disease monitoring. Recent foundation models like MedSAM achieve strong results using point or bounding-box prompts but still require manual…

Computer Vision and Pattern Recognition · Computer Science 2025-09-23 Wenjie Zhang , Liming Luo , Mengnan He , Jiarui Hai , Jiancheng Ye

We introduce GeoSAM2, a prompt-controllable framework for 3D part segmentation that casts the task as multi-view 2D mask prediction. Given a textureless object, we render normal and point maps from predefined viewpoints and accept simple 2D…

Computer Vision and Pattern Recognition · Computer Science 2025-08-28 Ken Deng , Yunhan Yang , Jingxiang Sun , Xihui Liu , Yebin Liu , Ding Liang , Yan-Pei Cao

Cryo-electron tomography (cryo-ET) has emerged as a powerful tool for studying the structural heterogeneity of proteins and their complexes, offering insights into macromolecular dynamics directly within cells. Driven by recent…

Biomolecules · Quantitative Biology 2025-07-01 Jackson Carrion , Joseph H. Davis

Foundational models such as the Segment Anything Model (SAM) are gaining traction in medical imaging segmentation, supporting multiple downstream tasks. However, such models are supervised in nature, still relying on large annotated…

Computer Vision and Pattern Recognition · Computer Science 2025-03-07 Aishik Konwer , Zhijian Yang , Erhan Bas , Cao Xiao , Prateek Prasanna , Parminder Bhatia , Taha Kass-Hout

Accurate tongue segmentation is crucial for reliable TCM analysis. Supervised models require large annotated datasets, while SAM-family models remain prompt-driven. We present Memory-SAM, a training-free, human-prompt-free pipeline that…

Computer Vision and Pattern Recognition · Computer Science 2026-05-15 Joongwon Chae , Lihui Luo , Xi Yuan , Dongmei Yu , Zhenglin Chen , Lian Zhang , Peiwu Qin

Cellular electron cryo-tomography enables the 3D visualization of cellular organization in the near-native state and at submolecular resolution. However, the contents of cellular tomograms are often complex, making it difficult to…

Quantitative Methods · Quantitative Biology 2017-12-29 Xiangrui Zeng , Miguel Ricardo Leung , Tzviya Zeev-Ben-Mordehai , Min Xu

Nucleus instance segmentation in histology images is crucial for a broad spectrum of clinical applications. Current dominant algorithms rely on regression of nuclear proxy maps. Distinguishing nucleus instances from the estimated maps…

Computer Vision and Pattern Recognition · Computer Science 2024-01-25 Zhongyi Shui , Yunlong Zhang , Kai Yao , Chenglu Zhu , Sunyi Zheng , Jingxiong Li , Honglin Li , Yuxuan Sun , Ruizhe Guo , Lin Yang

Cryo-electron tomography (cryoET) is a crucial technique for unveiling the structure of protein complexes. Automatically analyzing tomograms captured by cryoET is an essential step toward understanding cellular structures. In this paper, we…

Computer Vision and Pattern Recognition · Computer Science 2025-02-20 Yusuke Uchida , Takaaki Fukui

Foundation models such as the recently introduced Segment Anything Model (SAM) have achieved remarkable results in image segmentation tasks. However, these models typically require user interaction through handcrafted prompts such as…

Computer Vision and Pattern Recognition · Computer Science 2024-10-01 Mélanie Gaillochet , Christian Desrosiers , Hervé Lombaert

TomoSAM has been developed to integrate the cutting-edge Segment Anything Model (SAM) into 3D Slicer, a highly capable software platform used for 3D image processing and visualization. SAM is a promptable deep learning model that is able to…

Computer Vision and Pattern Recognition · Computer Science 2023-06-16 Federico Semeraro , Alexandre Quintart , Sergio Fraile Izquierdo , Joseph C. Ferguson

Cryo-electron microscopy (cryoEM) is an increasingly popular method for protein structure determination. However, identifying a sufficient number of particles for analysis (often >100,000) can take months of manual effort. Current…

Quantitative Methods · Quantitative Biology 2019-10-17 Tristan Bepler , Andrew Morin , Julia Brasch , Lawrence Shapiro , Alex J. Noble , Bonnie Berger

Pancreatic cancer carries a poor prognosis and relies on endoscopic ultrasound (EUS) for targeted biopsy and radiotherapy. However, the speckle noise, low contrast, and unintuitive appearance of EUS make segmentation of pancreatic tumors…

Computer Vision and Pattern Recognition · Computer Science 2025-07-31 Pascal Spiegler , Taha Koleilat , Arash Harirpoush , Corey S. Miller , Hassan Rivaz , Marta Kersten-Oertel , Yiming Xiao

The realm of computer vision has witnessed a paradigm shift with the advent of foundational models, mirroring the transformative influence of large language models in the domain of natural language processing. This paper delves into the…

Computer Vision and Pattern Recognition · Computer Science 2024-06-27 Lv Tang , Peng-Tao Jiang , Hao-Ke Xiao , Bo Li