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Cryo-electron microscopy (cryo-EM) has recently emerged as a powerful tool for obtaining three-dimensional (3D) structures of biological macromolecules in native states. A minimum cryo-EM image data set for deriving a meaningful…
Cryo-electron microscopy (cryo-EM) allows for the high-resolution reconstruction of 3D structures of proteins and other biomolecules. Successful reconstruction of both shape and movement greatly helps understand the fundamental processes of…
The Segment Anything Model (SAM), a foundation model pretrained on millions of images and segmentation masks, has significantly advanced semantic segmentation, a fundamental task in computer vision. Despite its strengths, SAM encounters two…
Driven by large-data pre-training, Segment Anything Model (SAM) has been demonstrated as a powerful and promptable framework, revolutionizing the segmentation models. Despite the generality, customizing SAM for specific visual concepts…
Scanning transmission electron microscopy (STEM) is an extremely versatile method for studying materials on the atomic scale. Many STEM experiments are supported or validated with electron scattering simulations. However, using the…
Single-particle electron cryomicroscopy (cryo-EM) is an increasingly popular technique for elucidating the three-dimensional structure of proteins and other biologically significant complexes at near-atomic resolution. It is an imaging…
Segment Anything Model (SAM) has demonstrated impressive zero-shot performance and brought a range of unexplored capabilities to natural image segmentation tasks. However, as a very important branch of image segmentation, the performance of…
Cryo-electron microscopy (cryo-EM) enables the atomic-resolution visualization of biomolecules; however, modern direct detectors generate data volumes that far exceed the available storage and transfer bandwidth, thereby constraining…
Semantic segmentation is an important topic in computer vision with many relevant application in Earth observation. While supervised methods exist, the constraints of limited annotated data has encouraged development of unsupervised…
Positron Emission Tomography (PET) is a powerful molecular imaging tool that plays a crucial role in modern medical diagnostics by visualizing radio-tracer distribution to reveal physiological processes. Accurate organ segmentation from PET…
Purpose: The recent Segment Anything Model (SAM) has demonstrated impressive performance with point, text or bounding box prompts, in various applications. However, in safety-critical surgical tasks, prompting is not possible due to (i) the…
Segment Anything Model (SAM) has gained significant recognition in the field of semantic segmentation due to its versatile capabilities and impressive performance. Despite its success, SAM faces two primary limitations: (1) it relies…
Structural dynamics of macromolecules is critical to their structural-function relationship. Cryogenic electron microscopy (CryoEM) provides snapshots of vitrified protein at different compositional and conformational states, and the…
Segmentation models such as Segment Anything Model (SAM) and SAM2 achieve strong prompt-driven zero-shot performance. However, their training on natural images limits domain transfer to medical data. Consequently, accurate segmentation…
Over the past decade, cryogenic electron microscopy (cryo-EM) has emerged as a primary method for determining near-native, near-atomic resolution 3D structures of biological macromolecules. In order to meet increasing demand for cryo-EM,…
Constructing of molecular structural models from Cryo-Electron Microscopy (Cryo-EM) density volumes is the critical last step of structure determination by Cryo-EM technologies. Methods have evolved from manual construction by structural…
Cryo-electron microscopy (cryo-EM) is a powerful technique for determining high-resolution 3D biomolecular structures from imaging data. Its unique ability to capture structural variability has spurred the development of heterogeneous…
Biomedical image segmentation is a crucial part of both scientific research and clinical care. With enough labelled data, deep learning models can be trained to accurately automate specific biomedical image segmentation tasks. However,…
Pixel-level segmentation is essential in remote sensing, where foundational vision models like CLIP and Segment Anything Model(SAM) have demonstrated significant capabilities in zero-shot segmentation tasks. Despite their advances,…
In this paper, we present SonoSAMTrack - that combines a promptable foundational model for segmenting objects of interest on ultrasound images called SonoSAM, with a state-of-the art contour tracking model to propagate segmentations on 2D+t…