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Enhancing cryogenic electron microscopy (cryo-EM) 3D density maps at intermediate resolution (4-8 {\AA}) is crucial in protein structure determination. Recent advances in deep learning have led to the development of automated approaches for…

Computer Vision and Pattern Recognition · Computer Science 2025-05-16 Chenwei Zhang , Khanh Dao Duc

Cryo-EM is an increasingly popular method for determining the atomic resolution 3D structure of macromolecular complexes (eg, proteins) from noisy 2D images captured by an electron microscope. The computational task is to reconstruct the 3D…

Computer Vision and Pattern Recognition · Computer Science 2024-10-04 Shayan Shekarforoush , David B. Lindell , Marcus A. Brubaker , David J. Fleet

Non-destructive 3D imaging of large multi-particulate samples is essential for quantifying particle-level properties, such as size, shape, and spatial distribution, across applications in mining, materials science, and geology. However,…

Image and Video Processing · Electrical Eng. & Systems 2025-08-25 Philipp D. Lösel , Aleese Barron , Yulai Zhang , Matthias Fabian , Benjamin Young , Nicolas Francois , Andrew M. Kingston

As deep learning methods continue to improve medical image segmentation performance, data annotation is still a big bottleneck due to the labor-intensive and time-consuming burden on medical experts, especially for 3D images. To…

Computer Vision and Pattern Recognition · Computer Science 2023-09-26 Yixuan Wu , Bo Zheng , Jintai Chen , Danny Z. Chen , Jian Wu

Semantic Segmentation is one of the most challenging vision tasks, usually requiring large amounts of training data with expensive pixel level annotations. With the success of foundation models and especially vision-language models, recent…

Computer Vision and Pattern Recognition · Computer Science 2024-09-17 Soroush Seifi , Daniel Olmeda Reino , Fabien Despinoy , Rahaf Aljundi

This work proposes a novel approach beyond supervised learning for effective pathological image analysis, addressing the challenge of limited robust labeled data. Pathological diagnosis of diseases like cancer has conventionally relied on…

Computer Vision and Pattern Recognition · Computer Science 2024-10-23 Joonhyeon Song , Seohwan Yun , Seongho Yoon , Joohyeok Kim , Sangmin Lee

In the rapidly evolving field of AI research, foundational models like BERT and GPT have significantly advanced language and vision tasks. The advent of pretrain-prompting models such as ChatGPT and Segmentation Anything Model (SAM) has…

Image and Video Processing · Electrical Eng. & Systems 2024-01-25 Saiyang Na , Yuzhi Guo , Feng Jiang , Hehuan Ma , Junzhou Huang

Scanning transmission electron microscopy (STEM) is now the primary tool for exploring functional materials on the atomic level. Often, features of interest are highly localized in specific regions in the material, such as ferroelectric…

Materials Science · Physics 2021-08-11 Nicole Creange , Ondrej Dyck , Rama K. Vasudevan , Maxim Ziatdinov , Sergei V. Kalinin

Large-scale foundation models have become the mainstream deep learning method, while in civil engineering, the scale of AI models is strictly limited. In this work, a vision foundation model is introduced for crack segmentation. Two…

Computer Vision and Pattern Recognition · Computer Science 2024-04-24 Kang Ge , Chen Wang , Yutao Guo , Yansong Tang , Zhenzhong Hu , Hongbing Chen

Medical image segmentation is a vital healthcare endeavor requiring precise and efficient models for appropriate diagnosis and treatment. Vision transformer (ViT)-based segmentation models have shown great performance in accomplishing this…

Computer Vision and Pattern Recognition · Computer Science 2023-08-03 Numan Saeed , Muhammad Ridzuan , Roba Al Majzoub , Mohammad Yaqub

Accurate segmentation and measurement of lithography scanning electron microscope (SEM) images are crucial for ensuring precise process control, optimizing device performance, and advancing semiconductor manufacturing yield. Lithography…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Xinyu He , Botong Zhao , Bingbing Li , Shujing Lyu , Jiwei Shen , Yue Lu

Intra-operative ultrasound is an increasingly important imaging modality in neurosurgery. However, manual interaction with imaging data during the procedures, for example to select landmarks or perform segmentation, is difficult and can be…

Computer Vision and Pattern Recognition · Computer Science 2019-04-19 Julia Rackerseder , Rüdiger Göbl , Nassir Navab , Christoph Hennersperger

The Segment Anything Model (SAM) family has become a widely adopted vision foundation model, but its ability to control segmentation granularity remains limited. Users often need to refine results manually - by adding more prompts or…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Junwei Yu , Trevor Darrell , XuDong Wang

The recent emergence of the Segment Anything Model (SAM) enables various domain-specific segmentation tasks to be tackled cost-effectively by using bounding boxes as prompts. However, in scene text segmentation, SAM can not achieve…

Computer Vision and Pattern Recognition · Computer Science 2024-12-31 Enze Xie , Jiaho Lyu , Daiqing Wu , Huawen Shen , Yu Zhou

Cryo-electron microscopy (cryo-EM) is a powerful technique in structural biology and drug discovery, enabling the study of biomolecules at high resolution. Significant advancements by structural biologists using cryo-EM have led to the…

Biomolecules · Quantitative Biology 2024-12-05 Yi Zhou , Yilai Li , Jing Yuan , Quanquan Gu

Pose estimation from unordered images is fundamental for 3D reconstruction, robotics, and scientific imaging. Recent geometric foundation models, such as DUSt3R, enable end-to-end dense 3D reconstruction but remain underexplored in…

Computer Vision and Pattern Recognition · Computer Science 2025-10-15 Jiakai Zhang , Shouchen Zhou , Haizhao Dai , Xinhang Liu , Peihao Wang , Zhiwen Fan , Yuan Pei , Jingyi Yu

Foundation models have taken over natural language processing and image generation domains due to the flexibility of prompting. With the recent introduction of the Segment Anything Model (SAM), this prompt-driven paradigm has entered image…

Image and Video Processing · Electrical Eng. & Systems 2023-04-13 Saikat Roy , Tassilo Wald , Gregor Koehler , Maximilian R. Rokuss , Nico Disch , Julius Holzschuh , David Zimmerer , Klaus H. Maier-Hein

Recent success of vision foundation models have shown promising performance for the 2D perception tasks. However, it is difficult to train a 3D foundation network directly due to the limited dataset and it remains under explored whether…

Computer Vision and Pattern Recognition · Computer Science 2025-07-17 Qingdong He , Jinlong Peng , Zhengkai Jiang , Xiaobin Hu , Jiangning Zhang

Determining the three-dimensional structure of proteins and protein complexes at atomic resolution is a fundamental task in structural biology. Over the last decade, remarkable progress has been made using "single particle" cryo-electron…

Numerical Analysis · Mathematics 2017-06-05 Alex Barnett , Leslie Greengard , Andras Pataki , Marina Spivak

The Segment Anything Model (SAM) and similar models build a family of promptable foundation models (FMs) for image and video segmentation. The object of interest is identified using prompts, such as bounding boxes or points. With these FMs…

Computer Vision and Pattern Recognition · Computer Science 2024-11-14 Caroline Magg , Hoel Kervadec , Clara I. Sánchez