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Biological age, which may be older or younger than chronological age due to factors such as genetic predisposition, environmental exposures, serves as a meaningful biomarker of aging processes and can inform risk stratification, treatment…

Genomics · Quantitative Biology 2025-11-11 Shuyue Jiang , Wenjing Ma , Shaojun Yu , Chang Su , Runze Yan , Jiaying Lu

Individual differences in brain functional networks may be related to complex personal identifiers, including health, age, and ability. Understanding and quantifying these differences is a necessary first step towards developing predictive…

The stability of social relationships is important to animals living in groups, and social network analysis provides a powerful tool to help characterize and understand their (in)stability and the consequences at the group level. However,…

Physics and Society · Physics 2019-11-05 Valeria Gelardi , Joël Fagot , Alain Barrat , Nicolas Claidière

The face is a rich source of information that can be utilized to infer a person's biological age, sex, phenotype, genetic defects, and health status. All of these factors are relevant for predicting an individual's remaining lifespan. In…

Computer Vision and Pattern Recognition · Computer Science 2023-01-20 Amir Fekrazad

Face age progression, which aims to predict the future looks, is important for various applications and has been received considerable attentions. Existing methods and datasets are limited in exploring the effects of occupations which may…

Computer Vision and Pattern Recognition · Computer Science 2017-12-04 Siyu Zhou , Weiqiang Zhao , Jiashi Feng , Hanjiang Lai , Yan Pan , Jian Yin , Shuicheng Yan

Dynamical entities interacting with each other on complex networks often exhibit multistability. The stability of a desired steady regime (e.g., a synchronized state) to large perturbations is critical in the operation of many real-world…

Chaotic Dynamics · Physics 2017-03-22 Chiranjit Mitra , Anshul Choudhary , Sudeshna Sinha , Jürgen Kurths , Reik V. Donner

My analysis uses methods developed for data mining microarray experiments, adapted for ageing research. Methods bridge knowledge of statistical mechanics with data mining methods developed in statistical mathematics. Analyses can reveal how…

Quantitative Methods · Quantitative Biology 2012-12-11 Diana David-Rus

Brain aging is a widely studied longitudinal process throughout which the brain undergoes considerable morphological changes and various machine learning approaches have been proposed to analyze it. Within this context, brain age prediction…

Computer Vision and Pattern Recognition · Computer Science 2020-11-30 Matthias Wilms , Jordan J. Bannister , Pauline Mouches , M. Ethan MacDonald , Deepthi Rajashekar , Sönke Langner , Nils D. Forkert

The network representation is becoming increasingly popular for the description of cardiovascular interactions based on the analysis of multiple simultaneously collected variables. However, the traditional methods to assess network links…

Many of the chemical reactions that take place within a living cell are irreversible. Due to evolutionary pressures, the number of allowable reactions within these systems are highly constrained and thus the resulting metabolic networks…

Molecular Networks · Quantitative Biology 2013-03-04 Jonathan J Crofts , Ernesto Estrada

Demystifying effective connectivity among neuronal populations has become the trend to understand the brain mechanisms of Parkinson's disease, schizophrenia, mild traumatic brain injury, and many other unlisted neurological diseases.…

Quantitative Methods · Quantitative Biology 2019-09-27 Po-Ya Hsu

The human brains are organized into hierarchically modular networks facilitating efficient and stable information processing and supporting diverse cognitive processes during the course of development. While the remarkable reconfiguration…

Neurons and Cognition · Quantitative Biology 2020-09-16 Xuyun Wen , Liming Hsu , Weili Lin , Han Zhang , Dinggang Shen

Complex networks are used to depict topological features of complex systems. The structure of a network characterizes the interactions among elements of the system, and facilitates the study of many dynamical processes taking place on it.…

Physics and Society · Physics 2012-06-22 Yan Zhang , Lin Wang , Yi-Qing Zhang , Xiang Li

In a recent paper, Marr, Muller-Linow and Hutt [Phys. Rev. E 75, 041917 (2007)] investigate an artificial dynamic system on metabolic networks. They find a less complex time evolution of this dynamic system in real networks, compared to…

Molecular Networks · Quantitative Biology 2008-02-06 Petter Holme , Mikael Huss

Human aging is a process controlled by both genetics and environment. Many studies have been conducted to identify a subset of genes related to aging from the human genome. Biologists implicitly categorize age-related genes into genes that…

Genomics · Quantitative Biology 2023-11-17 Salman Mohamadi , Donald A. Adjeroh

Human brain networks can be characterized at different temporal or spatial scales given by the age of the subject or the spatial resolution of the neuroimaging method. Integration of data across scales can only be successful if the combined…

Network medicine is an emerging area of research dealing with molecular and genetic interactions, network biomarkers of disease, and therapeutic target discovery. Large-scale biomedical data generation offers a unique opportunity to assess…

Molecular Networks · Quantitative Biology 2019-03-14 Abhijeet R. Sonawane , Scott T. Weiss , Kimberly Glass , Amitabh Sharma

Structured populations are ubiquitous across the biological sciences. Mathematical models of these populations allow us to understand how individual physiological traits drive the overall dynamics in aggregate. For example, linear age- or…

Analysis of PDEs · Mathematics 2022-04-25 Sabina L. Altus , Jeffrey C. Cameron , David M. Bortz

Like distributed systems, biological multicellular processes are subject to dynamic changes and a biological system will not pass the survival-of-the-fittest test unless it exhibits certain features that enable fast recovery from these…

Distributed, Parallel, and Cluster Computing · Computer Science 2017-06-13 Yuval Emek , Jara Uitto

Aging is considered as the property of the elements of a system to be less prone to change states as they get older. We incorporate aging into the noisy voter model, a stochastic model in which the agents modify their binary state by means…

Statistical Mechanics · Physics 2018-09-06 Oriol Artime , Antonio F. Peralta , Raúl Toral , José J. Ramasco , Maxi San Miguel
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