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In social networks, individuals constantly drop ties and replace them by new ones in a highly unpredictable fashion. This highly dynamical nature of social ties has important implications for processes such as the spread of information or…

Physics and Society · Physics 2016-01-22 Antonia Godoy-Lorite , Roger Guimera , Marta Sales-Pardo

Biological networks, such as cellular metabolic pathways or networks of corticocortical connections in the brain, are intricately organized, yet remarkably robust toward structural damage. Whereas many studies have investigated specific…

Neurons and Cognition · Quantitative Biology 2007-05-23 Marcus Kaiser , Claus C. Hilgetag

Dementia affects over 55 million people worldwide, yet whether distinct domains of physical fitness independently protect against neurodegeneration through shared or divergent biological mechanisms remains unknown. Using the UK Biobank (n =…

Applications · Statistics 2026-04-07 Yiqing Sun , Runyu Lin , Jiayue Qin , Feiyue Pan , Bingjie Li , Zhigang Yao

The elapsed-time model describes the behavior of interconnected neurons through the time since their last spike. It is an age-structured non-linear equation in which age corresponds to the elapsed time since the last discharge, and models…

Dynamical Systems · Mathematics 2025-04-28 María J. Cáceres , José A Cañizo , Nicolas Torres

Many systems on our planet are known to shift abruptly and irreversibly from one state to another when they are forced across a "tipping point," such as mass extinctions in ecological networks, cascading failures in infrastructure systems,…

Quantitative Methods · Quantitative Biology 2022-05-23 Xueming Liu , Daqing Li , Manqing Ma , Boleslaw K. Szymanski , H Eugene Stanley , Jianxi Gao

We analyse the stability of linear dynamical systems defined on sparse, random graphs with predator-prey, competitive, and mutualistic interactions. These systems are aimed at modelling the stability of fixed points in large systems defined…

Statistical Mechanics · Physics 2025-01-30 Andrea Marcello Mambuca , Chiara Cammarota , Izaak Neri

Antifragility is a property from which systems are able to resist stress and furthermore benefit from it. Even though antifragile dynamics is found in various real-world complex systems where multiple subsystems interact with each other,…

Adaptation and Self-Organizing Systems · Physics 2026-02-04 Hyobin Kim , Omar K. Pineda , Carlos Gershenson

We investigate the stability properties of two different classes of metabolic cycles using a combination of analytical and computational methods. Using principles from structural kinetic modeling (SKM), we show that the stability of…

Molecular Networks · Quantitative Biology 2010-07-29 Ed Reznik , Daniel Segrè

The accurate quantification of brain age from MRI has emerged as an important biomarker of brain health. However, existing approaches are often restricted to narrow age ranges and single-modality MRI data, limiting their capacity to capture…

Image and Video Processing · Electrical Eng. & Systems 2026-04-21 Dingyi Zhang , Ruiying Liu , Yun Wang

Multimorbidity, the co-occurrence of two or more chronic diseases such as diabetes, obesity or cardiovascular diseases in one patient, is a frequent phenomenon. To make care more efficient, it is of relevance to understand how different…

Medical Physics · Physics 2019-08-05 Nils Haug , Stefan Thurner , Alexandra Kautzky-Willer , Michael Gyimesi , Peter Klimek

Resilient ecological systems will be better able to maintain their structure and function in the emerging Anthropocene. Estimating the resilience of different systems will therefore provide valuable insight for conservation decision-makers,…

Dynamical Systems · Mathematics 2023-06-16 Cailan Jeynes-Smith , Michael Bode , Robyn P. Araujo

Although accumulation of molecular damage is suggested to be an important molecular mechanism of aging, a quantitative link between the dynamics of damage accumulation and mortality of species has so far remained elusive. To address this…

Molecular Networks · Quantitative Biology 2016-11-24 D. Podolskiy , I. Molodtcov , A. Zenin , V. Kogan , L. I. Menshikov , Vadim N. Gladyshev , Robert J. Shmookler Reis , P. O. Fedichev

Recent progresses in the description of glassy relaxation and ageing are reviewed for the wide class of network-forming materials such as $GeO_2$, Ge$_x$Se$_{1-x}$, silicates (SiO$_2$-Na$_2$O) or borates (B$_2$O$_3$-Li$_2$O), all of them…

Disordered Systems and Neural Networks · Physics 2016-06-09 M. Micoulaut

In many social mammals, early life social adversity and social integration largely predict individual health, lifespan and reproductive success. Efforts in identifying the physiological mechanisms mediating the relationship between the…

Populations and Evolution · Quantitative Biology 2022-01-25 Alice Baniel , Marie J. E. Charpentier

Reduced motor control is one of the most frequent features associated with aging and disease. Nonlinear and fractal analyses have proved to be useful in investigating human physiological alterations with age and disease. Similar findings…

Quantitative Methods · Quantitative Biology 2017-09-06 Luiz G. A. Alves , Peter B. Winter , Leonardo N. Ferreira , Renée M. Brielmann , Richard I. Morimoto , Luís A. N. Amaral

Dynamic balance in human locomotion can be assessed through the local dynamic stability (LDS) method. Whereas gait LDS has been used successfully in many settings and applications, little is known about its sensitivity to individual…

Quantitative Methods · Quantitative Biology 2018-12-27 Fabienne Reynard , Philippe Terrier

Ignoring the differences between countries, human reproductive and dispersal behaviors can be described by some standardized models, so whether there is a universal law of population growth hidden in the abundant and unstructured data from…

Physics and Society · Physics 2024-02-08 Jiajun Ma , Qinghua Chen , Xiaosong Chen , Jingfang Fan , Xiaomeng Li , Yi Shi

Investigations of the human connectome have elucidated core features of adult structural networks, particularly the crucial role of hub-regions. However, little is known regarding network organisation of the healthy elderly connectome, a…

Neurons and Cognition · Quantitative Biology 2015-12-15 Alistair Perry , Wei Wen , Anton Lord , Anbupalam Thalamuthu , Perminder Sachdev , Michael Breakspear

Proteins participating in a protein-protein interaction network can be grouped into homology classes following their common ancestry. Proteins added to the network correspond to genes added to the classes, so that the dynamics of the two…

Molecular Networks · Quantitative Biology 2013-05-30 Arianna Bottinelli , Bruno Bassetti , Marco Cosentino Lagomarsino , Marco Gherardi

A fundamental premise of statistical physics is that the particles in a physical system are interchangeable, and hence the state of each specific component is representative of the system as a whole. This assumption breaks down for complex…

Physics and Society · Physics 2025-12-16 Neil G. MacLaren , Baruch Barzel , Naoki Masuda