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The study of citation networks is of interest to the scientific community. However, the underlying mechanism driving individual citation behavior remains imperfectly understood, despite the recent proliferation of quantitative research…
Neural activity exhibits a vast range of timescales that can be several fold larger than the membrane time constant of individual neurons. Two types of mechanisms have been proposed to explain this conundrum. One possibility is that large…
Author's early work on aging is developed to yield a relationship between life spans and the velocity of aging. The mathematical analysis shows that the mean extent of the advancement of aging throughout one's life is conserved, or…
Over the years, Machine Learning models have been successfully employed on neuroimaging data for accurately predicting brain age. Deviations from the healthy brain aging pattern are associated to the accelerated brain aging and brain…
The central nervous system is composed of many individual units -- from cells to areas -- that are connected with one another in a complex pattern of functional interactions that supports perception, action, and cognition. One natural and…
Biological networks have evolved to be highly functional within uncertain environments while remaining extremely adaptable. One of the main contributors to the robustness and evolvability of biological networks is believed to be their…
Cardiovascular diseases remain the leading global cause of mortality. Age is an important covariate whose effect is most easily investigated in a healthy cohort to properly distinguish the former from disease-related changes. Traditionally,…
System dynamics and agent based simulation models can both be used to model and understand interactions of entities within a population. Our modeling work presented here is concerned with understanding the suitability of the different types…
Background. Human aging is linked to many prevalent diseases. The aging process is highly influenced by genetic factors. Hence, it is important to identify human aging-related genes. We focus on supervised prediction of such genes. Gene…
Charting the lifespan evolutionary trajectory of brain function serves as the normative standard for preventing mental disorders during brain development and aging. Although numerous MRI studies have mapped the structural connectome for…
We characterize different cell states, related to cancer and ageing phenotypes, by a measure of entropy of network ensembles, integrating gene expression values and protein interaction networks. The entropy measure estimates the parameter…
Brain age is the estimate of biological age derived from neuroimaging datasets using machine learning algorithms. Increasing \textit{brain age gap} characterized by an elevated brain age relative to the chronological age can reflect…
We consider large deviations of the dynamical activity in the East model. We bias this system to larger than average activity and investigate the structure that emerges. To best characterise this structure, we exploit the fact that there…
A simple mathematical model of the aging process for long-lived organisms is considered. The key point in this model is the assumption that the body does not have internal clocks that count out the chronological time at scales of decades.…
Understanding how few distributed areas can steer large-scale brain activity is a fundamental question that has practical implications, which range from inducing specific patterns of behavior to counteracting disease. Recent endeavors based…
A longitudinal social network evolves over time through the creation and/ or deletion of links among a set of actors (e.g. individuals or organizations). Longitudinal social networks are studied by network science and social science…
Complex pattern formation is an essential characteristic of plants and their ageing, growth, and evolution. Perception of these patterns is an intrinsic nature of plant-dependent animals for coexistence. Areca nut consisting of complex…
Modern neuroimaging technologies, combined with state-of-the-art data processing pipelines, have made it possible to collect longitudinal observations of an individual's brain connectome at different ages. It is of substantial scientific…
Cognitive ageing seems to be a story of global degradation. As one ages there are a number of physical, chemical and biological changes that take place. Therefore it is logical to assume that the brain is no exception to this phenomenon.…
Background: Photoplethysmography (PPG), increasingly available through wearable devices, provides a non-invasive means of monitoring human hemodynamics. In this study, we introduce artificial intelligence-derived photoplethysmography…