English

Quantitative transcriptional analysis of aging C. elegans

Quantitative Methods 2012-12-11 v1 Genomics

Abstract

My analysis uses methods developed for data mining microarray experiments, adapted for ageing research. Methods bridge knowledge of statistical mechanics with data mining methods developed in statistical mathematics. Analyses can reveal how the transcriptional regulation of genes might coincide, thereby implicating proteins as parts of networks acting together towards a common biological function. Such experiments are most useful for complex biological traits that result from the presumed functioning of several molecular pathways. Ageing is one such biological phenomenon that apparently incorporates numerous molecular mechanisms underlying environmental stimulus sensing, metabolic regulation, stress responses, reproductive signalling, hibernation, and transcriptional regulation.

Keywords

Cite

@article{arxiv.1212.1920,
  title  = {Quantitative transcriptional analysis of aging C. elegans},
  author = {Diana David-Rus},
  journal= {arXiv preprint arXiv:1212.1920},
  year   = {2012}
}

Comments

82 pages

R2 v1 2026-06-21T22:51:11.386Z