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Malaria is one of the deadliest infectious diseases globally, causing hundreds of thousands of deaths each year. It disproportionately affects young children, with two-thirds of fatalities occurring in under-fives. Individuals acquire…

Populations and Evolution · Quantitative Biology 2023-06-07 Zhuolin Qu , Denis Patterson , Lauren Childs , Christina Edholm , Joan Ponce , Olivia Prosper , Lihong Zhao

In this work we propose a measure-valued stochastic process representing the dynamics of a virus population, structured by phenotypic traits and geographical space, and where viruses are transported between spatial locations by mechanical…

Probability · Mathematics 2022-11-10 Mario Ayala , Jerome Coville , Raphael Forien

The primary tool for predicting infectious disease spread and intervention effectiveness is the mass action Susceptible-Infected-Recovered model of Kermack and McKendrick. Its usefulness derives largely from its conceptual and mathematical…

Populations and Evolution · Quantitative Biology 2015-09-03 Joel C. Miller , Anja C. Slim , Erik M. Volz

A random graph model with prescribed degree distribution and degree dependent edge weights is introduced. Each vertex is independently equipped with a random number of half-edges and each half-edge is assigned an integer valued weight…

Probability · Mathematics 2015-05-28 Tom Britton , Maria Deijfen , Fredrik Liljeros

In the world of epidemics, the mathematical modeling of disease co-infection is gaining importance due to its contributions to mathematics and public health. Because the co-infection may have a double burden on families, countries, and the…

Populations and Evolution · Quantitative Biology 2023-07-12 Anna Daniel Fome , Wolfgang Bock , Axel Klar

We consider an agro-ecologically motivated coupling between a prey-predator system and a vector-borne epidemic system. The coupled system contains one ODE, two reaction-diffusion PDEs and one reaction-diffusionadvection PDE; it has no…

Analysis of PDEs · Mathematics 2022-12-23 Léo Girardin , Baptiste Maucourt

A four dimensional ecoepidemiological model consisting of susceptible prey, infected prey, vaccinated prey and predator is formulated and analyzed in the present work. The functional response is assumed to be of Lotka-Volterra type. We…

Dynamical Systems · Mathematics 2017-10-02 Sachin Kumar , Harsha Kharbanda

Accurate epidemic forecasting requires models that account for the layered and heterogeneous nature of real social interactions. The basic reproduction number $\mathcal R_0$ calculated from models that assume homogeneous mixing or…

Physics and Society · Physics 2025-10-15 Eric Alejandro Rozan , Mario Ignacio Simoy , Sebastian Bouzat , Marcelo Nestor Kuperman

Partial differential equation (PDE) models for infectious diseases, while less common than their ordinary differential equation (ODE) counterparts, have found successful applications for many years. Such models are typically of…

Populations and Evolution · Quantitative Biology 2026-01-27 Alex Viguerie , Malú Grave , Alvaro L. G. A. Coutinho , Alessandro Veneziani , Thomas J. R. Hughes

In large-scale disease etiology studies, epidemiologists often need to use multiple binary measures of unobserved causes of disease that are not perfectly sensitive or specific to estimate cause-specific case fractions, referred to as…

Methodology · Statistics 2019-06-21 Zhenke Wu , Irena Chen

The transmission of vector infectious diseases, which produces complex spatiotemporal patterns, is analyzed by a periodically forced two-dimensional cellular automata model. The system, which comprises three population levels, is introduced…

Cellular Automata and Lattice Gases · Physics 2008-10-03 L. B. L. Santos , M. C. Costa , S. T. R. Pinho , R. F. S. Andrade , F. R. Barreto , M. G. Teixeira , M. L. Barreto

This study examines the behavior of solutions in a multi-patch epidemic model that includes a saturation incidence mechanism. When the fatality rate due to the disease is not null, our findings show that the solutions of the model tend to…

Populations and Evolution · Quantitative Biology 2024-09-19 Yawo Ezunkpe , Cynthia T. Nnolum , Rachidi B. Salako , Shuwen Xue

We propose a novel multi-scale modeling framework for infectious disease spreading, borrowing ideas and modeling tools from the so-called Refractory Density (RD) approach. We introduce a microscopic model that describes the probability of…

Populations and Evolution · Quantitative Biology 2025-03-24 Anton Chizhov , Laurent Pujo-Menjouet , Tilo Schwalger , Mattia Sensi

Coupling within-host infection dynamics with population-level transmission remains a major challenge in infectious disease modeling, especially for airborne pathogens with potential to spread indoor. The frequent emergence of such diseases…

Analysis of PDEs · Mathematics 2025-12-18 Andrew Omame , Sarafa Iyaniwura

When controlling an emerging outbreak of an infectious disease it is essential to know the key epidemiological parameters, such as the basic reproduction number $R_0$ and the control effort required to prevent a large outbreak. These…

Populations and Evolution · Quantitative Biology 2016-04-18 Pieter Trapman , Frank Ball , Jean-Stéphane Dhersin , Viet Chi Tran , Jacco Wallinga , Tom Britton

The interplay between disease spreading and personal risk perception is of key importance for modelling the spread of infectious diseases. We propose a planar system of ordinary differential equations (ODEs) to describe the co-evolution of…

Dynamical Systems · Mathematics 2023-05-09 Massimo A. Achterberg , Mattia Sensi

In this paper, we consider a compartmental SIRS epidemic model with asymptomatic infection and seasonal succession, which is a periodic discontinuous differential system. The basic reproduction number $\mathcal{R}_0$ is defined and valuated…

Dynamical Systems · Mathematics 2017-08-15 Yilei Tang , Dongmei Xiao , Weinian Zhang , Di Zhu

This paper introduces an innovative model for infectious diseases in predator-prey populations. We not only prove the existence of global non-negative solutions but also establish essential criteria for the system's decline and…

Populations and Evolution · Quantitative Biology 2023-06-16 Yujie Gao , Malay Banerjee , Ton Viet Ta

We present a stochastic epidemic model to study the effect of various preventive measures, such as uniform reduction of contacts and transmission, vaccination, isolation, screening and contact tracing, on a disease outbreak in a…

Populations and Evolution · Quantitative Biology 2022-07-08 Martina Favero , Gianpaolo Scalia Tomba , Tom Britton

Infectious disease transmission in human populations has a complex two-way interaction with changes in host behaviour. It is increasingly recognised that incorporating adaptive behavioural change into epidemic models is important for…

Populations and Evolution · Quantitative Biology 2026-04-14 Michael J. Plank , Matt Ryan , Lloyd Chapman , Roslyn I. Hickson , Thomas House , Emma McBryde , James M. McCaw
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