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This paper examines an epidemic patch model with mass-action transmission mechanism and asymmetric connectivity matrix. Results on the global dynamics of solutions and the spatial structures of endemic solutions are obtained. In particular,…

Classical Analysis and ODEs · Mathematics 2023-11-14 Rachidi Salako , Yixiang Wu

Sensitivity Analysis (SA) is a useful tool to measure the impact of changes in model parameters on the infection dynamics, particularly to quantify the expected efficacy of disease control strategies. SA has only been applied to epidemic…

Populations and Evolution · Quantitative Biology 2021-11-23 Hayriye Gulbudak , Zhuolin Qu , Fabio Milner , Necibe Tuncer

This article introduces epidemia, an R package for Bayesian, regression-oriented modeling of infectious diseases. The implemented models define a likelihood for all observed data while also explicitly modeling transmission dynamics: an…

Ross-Macdonald models are the building blocks of most vector-borne disease models. Even for the same disease, different authors use different model formulations, but a study of the dynamical consequences of assuming different hypotheses is…

Populations and Evolution · Quantitative Biology 2020-07-22 Mario Ignacio Simoy , Juan Pablo Aparicio

Many models of within-host malaria infection dynamics have been formulated since the pioneering work of Anderson et al. in 1989. Biologically, the goal of these models is to understand what governs the severity of infections, the patterns…

Analysis of PDEs · Mathematics 2022-02-18 Ramsès Djidjou-Demasse , Arnaud Ducrot , Nicole Mideo , Gaëtan Texier

Nosocomial pathogens such as Methicillin-Resistant {\em Staphylococcus aureus} (MRSA) and Vancomycin-resistant {\em Enterococci} (VRE) are the cause of significant morbidity and mortality among hospital patients. It is important to be able…

There are economic and physical limitations when applying prevention and control strategies for urban vector borne diseases. Consequently, there are increasing concerns and interest in designing efficient strategies and regulations that…

Populations and Evolution · Quantitative Biology 2017-10-12 Jorge Velázquez-Castro , Andrés Anzo-Hernández , Beatriz Bonilla-Capilla , Moisés Soto-Bajo , Andrés Fraguela-Collar

Vector-borne diseases arise from the coupled dynamics of human mobility and mosquito ecology, producing outbreaks shaped by both spatial distributions and temporal patterns of movement. Here we develop a coarse-grained hub--leaf reduction…

Populations and Evolution · Quantitative Biology 2025-08-29 Bibandhan Poudyal , Gourab Ghoshal

Wastewater-based epidemiology (WBE) is a fast emerging method for passively monitoring diseases in a population. By measuring the concentrations of pathogenic materials in wastewater, WBE negates demographic biases in clinical testing and…

Populations and Evolution · Quantitative Biology 2025-06-18 Anthony J Wood , Jessica Enright , Aeron R Sanchez , Ewan Colman , Rowland R Kao

This paper introduces a novel hybrid model combining Partial Differential Equations (PDEs) and Ordinary Differential Equations (ODEs) to simulate infectious disease dynamics across geographic regions. By leveraging the spatial detail of…

Dynamical Systems · Mathematics 2025-11-18 Kristina Kehrer , Martin Weiser , Tim Conrad

Compartmental models have long served as important tools in mathematical epidemiology, with their usefulness highlighted by the recent COVID-19 pandemic. However, most of the classical models fail to account for certain features of this…

Dynamical Systems · Mathematics 2023-08-21 Monique Chyba , Taylor Klotz , Yuriy Mileyko , Corey Shanbrom

Insect-borne diseases are diseases carried by insects affecting humans, animals or plants. They have the potential to generate massive outbreaks such as the Zika epidemic in 2015-2016 mostly distributed in the Americas, the Pacific and…

Analysis of PDEs · Mathematics 2020-02-19 Olivier Martin , Yasmil Fernandez-Diclo , Jerome Coville , Samuel Soubeyrand

Multivariate count time series models are an important tool for the analysis and prediction of infectious disease spread. We consider the endemic-epidemic framework, an autoregressive model class for infectious disease surveillance counts,…

Applications · Statistics 2020-03-16 Johannes Bracher , Leonhard Held

In this chapter, an application of Mathematical Epidemiology to crop vector-borne diseases is presented to investigate the interactions between crops, vectors, and virus. The main illustrative example is the cassava mosaic disease (CMD).…

Populations and Evolution · Quantitative Biology 2019-12-12 Michael Chapwanya , Yves Dumont

It is possible to model vector-borne infection using the classical Ross-Macdonald model. This attempt, however fails in several respects. First, using measured (or estimated) parameters, the model predicts a much greater number of cases…

In this paper we first introduce the general stochastic epidemic model for the spread of infectious diseases. Then we give methods for inferring model parameters such as the basic reproduction number $R_0$ and vaccination coverage $v_c$…

Methodology · Statistics 2014-11-14 Tom Britton , Federica Giardina

The reproduction number of deterministic models is an essential quantity to predict whether an epidemic will spread or die out. Thresholds for disease extinction contribute crucial knowledge on disease control, elimination, and mitigation…

Populations and Evolution · Quantitative Biology 2013-08-08 Ling Xue , Caterina Scoglio

We delve into the interactions between a prey-predator and a vector-borne epidemic system, driven by agro-ecological motivations. This system involves an ODE, two reaction--diffusion PDEs and one reaction--diffusion--advection PDE. It has…

Analysis of PDEs · Mathematics 2024-02-13 Baptiste Maucourt

This paper is devoted to the study of optimal release strategies to control vector-borne diseases, such as dengue, Zika, chikungunya and malaria. Two techniques are considered: the sterile insect one (SIT), which consists in releasing…

Optimization and Control · Mathematics 2023-07-24 Luis Almeida , Jesús Bellver Arnau , Yannick Privat , Carlota Rebelo

In mathematical epidemiology, epidemic control often aims at driving the number of infected individuals to zero, asymptotically. However , during the transitory phase, the number of infected can peak at high values. In this paper, we…

Optimization and Control · Mathematics 2015-10-06 Michel De Lara , Lilian Sofia Sepulveda Salcedo