Related papers: Analysis of Control Measures for Vector-borne Dise…
Dengue continues to pose a major global threat, infecting nearly 390 million people annually. Recognizing the pivotal role of vector competence (vc), recent research focuses on mosquito parameters to inform transmission modeling and vector…
Infectious disease spread is a multi-scale process composed of within-host (biological) and between-host (social) drivers and disentangling them from each other is a central challenge in epidemiology. Here, we introduce VIBES, a multi-scale…
This study investigates an SEIS PDE model with a free boundary, which captures the dynamics of epidemic transmission, including diseases like COVID-19. This parabolic PDE system is analyzed in a rotationally symmetric domain, and the…
Dengue is a vector-borne viral disease increasing dramatically over the past years due to improvement in human mobility. The movement of host individuals between and within the patches are captured via a residence-time matrix. A system of…
We investigate how key epidemiological parameters shape both seasonal epidemics and the persistence of dengue transmission. Our findings confirm known mechanistic drivers of epidemic variability and introduce a ranking of parameter…
In this work we analyze mathematically the consequences and effectiveness of strategies to control an epidemic in the framework of classical SEIR models with multiple parallel infectious stages. We define the mathematical concept of a…
A key problem in modelling the evolution dynamics of infectious diseases is the mathematical representation of the mechanism of transmission of the contagion. Models with a finite number of subpopulations can be described via systems of…
In contrast to the many theoretical studies on the transmission of human-mosquitoes malaria infection, few studies have considered a multiple structure model formulations including (i) the chronological age of humans and mosquitoes…
We present a local spread model of disease transmission on a regular network and compare different control options ranging from treating the whole population to local control in a well-defined neighborhood of an infectious individual.…
Dengue transmission is shaped by the population dynamics of the Aedes aegypti mosquito, making vector control a central strategy for disease mitigation. The impact of interventions such as larvicide, adulticide, and breeding-site reduction…
Whole genome sequencing of pathogens from multiple hosts in an epidemic offers the potential to investigate who infected whom with unparalleled resolution, potentially yielding important insights into disease dynamics and the impact of…
A model with six mutually-exclusive compartments related to dengue is studied. Three vector control tools are considered: insecticides (larvicide and adulticide) and mechanical control. The basic reproduction number associated to the model…
Rift Valley fever virus (RVFV) has been expanding its geographical distribution with important implications for both human and animal health. The emergence of Rift Valley fever (RVF) in the Middle East, and its continuing presence in many…
Assessing the risk of epidemic spread on networks and developing strategies for its containment is of tremendous practical importance, both due to direct effects in public health and its impact on economies. In this work we present the…
The relationship between epidemiology, mathematical modeling and computational tools allows to build and test theories on the development and battling of a disease. This PhD thesis is motivated by the study of epidemiological models applied…
Genetic variations in the COVID-19 virus are one of the main causes of the COVID-19 pandemic outbreak in 2020 and 2021. In this article, we aim to introduce a new type of model, a system coupled with ordinary differential equations (ODEs),…
In this paper we study a discrete-time SIS (susceptible-infected-susceptible) model, where the infection and healing parameters and the underlying network may change over time. We provide conditions for the model to be well-defined and…
Infection by distinct Dengue virus serotypes and host immunity are intricately linked. In particular, certain levels of cross-reactive antibodies in the host may actually enhance infection severity leading to Dengue hemorrhagic fever (DHF).…
Rabies remains a pressing global public health issue, demanding effective modeling and control strategies. This study focused on developing a mathematical model using ordinary differential equations (ODEs) to estimate parameters and assess…
Dengue is a vector borne infectious disease. The disease is transmitted byAedes mosquitoes. In the present work, SEIR - SEI compartmental epidemiological model is used to describe dengue disease transmission dynamics. The human population…