Related papers: Knowledge Graph Completion based on Tensor Decompo…
In this work, we propose a new deep learning model for Genomic Prediction (GP), which involves correlating genotypic data with phenotypic. The genotypes are typically fed as a sequence of characters to the 1D-Convolution Neural Network…
Exploring the effects a chemical compound has on a species takes a considerable experimental effort. Appropriate methods for estimating and suggesting new effects can dramatically reduce the work needed to be done by a laboratory. In this…
Disease-gene association through Genome-wide association study (GWAS) is an arduous task for researchers. Investigating single nucleotide polymorphisms (SNPs) that correlate with specific diseases needs statistical analysis of associations.…
Background: Automatic extraction of chemical-disease relations (CDR) from unstructured text is of essential importance for disease treatment and drug development. Meanwhile, biomedical experts have built many highly-structured knowledge…
Recently, a considerable literature has grown up around the theme of Graph Convolutional Network (GCN). How to effectively leverage the rich structural information in complex graphs, such as knowledge graphs with heterogeneous types of…
Biomedical networks (or graphs) are universal descriptors for systems of interacting elements, from molecular interactions and disease co-morbidity to healthcare systems and scientific knowledge. Advances in artificial intelligence,…
Heterogeneous molecular entities and their interactions, commonly depicted as a network, are crucial for advancing our systems-level understanding of biology. With recent advancements in high-throughput data generation and a significant…
Knowledge graphs often suffer from incompleteness issues, which can be alleviated through information completion. However, current state-of-the-art deep knowledge convolutional embedding models rely on external convolution kernels and…
Biomedical Knowledge Graphs (BKGs) integrate diverse datasets to elucidate complex relationships within the biomedical field. Effective link prediction on these graphs can uncover valuable connections, such as potential novel drug-disease…
Knowledge graph embeddings (KGEs) were originally developed to infer true but missing facts in incomplete knowledge repositories. In this paper, we link knowledge graph completion and counterfactual reasoning via our new task CFKGR. We…
A Knowledge Graph (KG) is the directed graphical representation of entities and relations in the real world. KG can be applied in diverse Natural Language Processing (NLP) tasks where knowledge is required. The need to scale up and complete…
In genome-scale constraint-based metabolic models, gene deletion strategies are essential for achieving growth-coupled production, where cell growth and target metabolite synthesis occur simultaneously. Despite the inherently networked…
To provide more accurate, diverse, and explainable recommendation, it is compulsory to go beyond modeling user-item interactions and take side information into account. Traditional methods like factorization machine (FM) cast it as a…
Completion through the embedding representation of the knowledge graph (KGE) has been a research hotspot in recent years. Realistic knowledge graphs are mostly related to time, while most of the existing KGE algorithms ignore the time…
Recently, Hyper-relational Knowledge Graphs (HKGs) have been proposed as an extension of traditional Knowledge Graphs (KGs) to better represent real-world facts with additional qualifiers. As a result, researchers have attempted to adapt…
Knowledge Graph Completion (KGC) aims at automatically predicting missing links for large-scale knowledge graphs. A vast number of state-of-the-art KGC techniques have got published at top conferences in several research fields, including…
Knowledge graph completion (KGC) aims to discover missing relationships between entities in knowledge graphs (KGs). Most prior KGC work focuses on learning embeddings for entities and relations through a simple scoring function. Yet, a…
Increasing evidence has shown that gene-gene interactions have important effects on biological processes of human diseases. Due to the high dimensionality of genetic measurements, existing interaction analysis methods usually suffer from a…
We present an end-to-end, interpretable, deep-learning architecture to learn a graph kernel that predicts the outcome of chronic disease drug prescription. This is achieved through a deep metric learning collaborative with a Support Vector…
Objective: Disease knowledge graphs are a way to connect, organize, and access disparate information about diseases with numerous benefits for artificial intelligence (AI). To create knowledge graphs, it is necessary to extract knowledge…