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Poor DRAM technology scaling over the course of many years has caused DRAM-based main memory to increasingly become a larger system bottleneck. A major reason for the bottleneck is that data stored within DRAM must be moved across a…

Hardware Architecture · Computer Science 2018-02-02 Saugata Ghose , Kevin Hsieh , Amirali Boroumand , Rachata Ausavarungnirun , Onur Mutlu

Mass spectrometry (MS) is essential for proteomics and metabolomics but faces impending challenges in efficiently processing the vast volumes of data. This paper introduces SpecPCM, an in-memory computing (IMC) accelerator designed to…

Hardware Architecture · Computer Science 2024-11-18 Keming Fan , Ashkan Moradifirouzabadi , Xiangjin Wu , Zheyu Li , Flavio Ponzina , Anton Persson , Eric Pop , Tajana Rosing , Mingu Kang

Processing-in-memory (PIM) architectures bring computation closer to data, reducing the processor-memory transfer bottleneck in traditional processor-centric designs. Novel hardware solutions, such as UPMEM's in-memory processing…

Emerging Technologies · Computer Science 2026-04-10 Peterson Yuhala , Mpoki Mwaisela , Pascal Felber , Valerio Schiavoni

Neural networks (NNs) are growing in importance and complexity. A neural network's performance (and energy efficiency) can be bound either by computation or memory resources. The processing-in-memory (PIM) paradigm, where computation is…

Hardware Architecture · Computer Science 2023-03-28 Geraldo F. Oliveira , Juan Gómez-Luna , Saugata Ghose , Amirali Boroumand , Onur Mutlu

With small-scale quantum processors transitioning from experimental physics labs to industrial products, these processors allow us to efficiently compute important algorithms in various fields. In this paper, we propose a quantum algorithm…

Quantum Physics · Physics 2020-05-22 Aritra Sarkar , Zaid Al-Ars , Carmen G. Almudever , Koen Bertels

Processing-in-memory (PIM) has shown extraordinary potential in accelerating neural networks. To evaluate the performance of PIM accelerators, we present an ISA-based simulation framework including a dedicated ISA targeting neural networks…

Hardware Architecture · Computer Science 2024-02-29 Xinyu Wang , Xiaotian Sun , Yinhe Han , Xiaoming Chen

Spiking Neural Networks (SNNs), with their inherent recurrence, offer an efficient method for processing the asynchronous temporal data generated by Dynamic Vision Sensors (DVS), making them well-suited for event-based vision applications.…

Hardware Architecture · Computer Science 2024-11-06 Deepika Sharma , Shubham Negi , Trishit Dutta , Amogh Agrawal , Kaushik Roy

Compute-in-memory (CIM) has shown significant potential in efficiently accelerating deep neural networks (DNNs) at the edge, particularly in speeding up quantized models for inference applications. Recently, there has been growing interest…

Hardware Architecture · Computer Science 2025-02-12 Zhiqiang Yi , Yiwen Liang , Weidong Cao

Compute in-memory (CIM) is a promising technique that minimizes data transport, the primary performance bottleneck and energy cost of most data intensive applications. This has found wide-spread adoption in accelerating neural networks for…

Signal Processing · Electrical Eng. & Systems 2021-02-16 Brian Crafton , Samuel Spetalnick , Arijit Raychowdhury

The performance bottleneck of deep-learning-based recommender systems resides in their backbone Deep Neural Networks. By integrating Processing-In-Memory~(PIM) architectures, researchers can reduce data movement and enhance energy…

Hardware Architecture · Computer Science 2025-05-19 Feng Cheng , Tunhou Zhang , Junyao Zhang , Jonathan Hao-Cheng Ku , Yitu Wang , Xiaoxuan Yang , Hai , Li , Yiran Chen

Resistive random access memory (ReRAM) is a promising emerging non-volatile memory (NVM) technology that shows high potential for both data storage and computing. However, its crossbar array architecture leads to the sneak path problem,…

Information Theory · Computer Science 2024-11-20 Xingwei Zhong , Kui Cai , Guanghui Song , Weijie Wang , Yao Zhu

Recent DNA pre-alignment filter designs employ DRAM for storing the reference genome and its associated meta-data. However, DRAM incurs increasingly high energy consumption background and refresh energy as devices scale. To overcome this…

Emerging Technologies · Computer Science 2022-12-27 Fazal Hameed , Asif Ali Khan , Sebastien Ollivier , Alex K. Jones , Jeronimo Castrillon

As data-intensive applications increasingly strain conventional computing systems, processing-in-memory (PIM) has emerged as a promising paradigm to alleviate the memory wall by minimizing data transfer between memory and processing units.…

Emerging Technologies · Computer Science 2026-02-05 Thomas Neuner , Henriette Padberg , Lior Kornblum , Eilam Yalon , Pedram Khalili Amiri , Shahar Kvatinsky

To index the increasing volume of data, modern data indexes are typically stored on SSDs and cached in DRAM. However, searching such an index has resulted in significant I/O traffic due to limited access locality and inefficient cache…

Hardware Architecture · Computer Science 2024-08-05 Yun-Chih Chen , Yuan-Hao Chang , Tei-Wei Kuo

In recent years, the CNNs have achieved great successes in the image processing tasks, e.g., image recognition and object detection. Unfortunately, traditional CNN's classification is found to be easily misled by increasingly complex image…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-11-12 Xingyao Zhang , Shuaiwen Leon Song , Chenhao Xie , Jing Wang , Weigong Zhang , Xin Fu

Edge deployment of low-batch large language models (LLMs) faces critical memory bandwidth bottlenecks when executing memory-intensive general matrix-vector multiplications (GEMV) operations. While digital processing-in-memory (PIM)…

Hardware Architecture · Computer Science 2026-01-21 Ye Lin , Chao Fang , Xiaoyong Song , Qi Wu , Anying Jiang , Yichuan Bai , Li Du

The rise of data-intensive AI workloads has exacerbated the ``memory wall'' bottleneck. Digital Compute-in-Memory (DCiM) using SRAM offers a scalable solution, but its vast design space makes manual design impractical, creating a need for…

Hardware Architecture · Computer Science 2026-01-19 Yiqi Zhou , JunHao Ma , Xingyang Li , Yule Sheng , Yue Yuan , Yikai Wang , Bochang Wang , Yiheng Wu , Shan Shen , Wei Xing , Daying Sun , Li Li , Zhiqiang Xiao

The second-order training methods can converge much faster than first-order optimizers in DNN training. This is because the second-order training utilizes the inversion of the second-order information (SOI) matrix to find a more accurate…

Hardware Architecture · Computer Science 2022-10-28 Yilong Zhao , Li Jiang , Mingyu Gao , Naifeng Jing , Chengyang Gu , Qidong Tang , Fangxin Liu , Tao Yang , Xiaoyao Liang

Microbial clades modeling is a challenging problem in biology based on microarray genome sequences, especially in new species gene isolates discovery and category. Marker family genome sequences play important roles in describing specific…

Quantitative Methods · Quantitative Biology 2019-04-22 Jingwei Liu

Nanopore genome sequencing is the key to enabling personalized medicine, global food security, and virus surveillance. The state-of-the-art base-callers adopt deep neural networks (DNNs) to translate electrical signals generated by nanopore…

Hardware Architecture · Computer Science 2020-08-10 Qian Lou , Sarath Janga , Lei Jiang