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Bit-level sparsity in neural network models harbors immense untapped potential. Eliminating redundant calculations of randomly distributed zero-bits significantly boosts computational efficiency. Yet, traditional digital SRAM-PIM…

Hardware Architecture · Computer Science 2024-04-16 Cenlin Duan , Jianlei Yang , Yiou Wang , Yikun Wang , Yingjie Qi , Xiaolin He , Bonan Yan , Xueyan Wang , Xiaotao Jia , Weisheng Zhao

The rapidly emerging field of computational pathology has the potential to enable objective diagnosis, therapeutic response prediction and identification of new morphological features of clinical relevance. However, deep learning-based…

Image and Video Processing · Electrical Eng. & Systems 2020-05-25 Ming Y. Lu , Drew F. K. Williamson , Tiffany Y. Chen , Richard J. Chen , Matteo Barbieri , Faisal Mahmood

Various processing-in-memory (PIM) accelerators based on various devices, micro-architectures, and interfaces have been proposed to accelerate deep neural networks (DNNs). How to deploy DNNs onto PIM-based accelerators is the key to explore…

Hardware Architecture · Computer Science 2024-11-15 Xiaotian Sun , Xinyu Wang , Wanqian Li , Yinhe Han , Xiaoming Chen

Using Resistive Random Access Memory (RRAM) crossbars in Computing-in-Memory (CIM) architectures offers a promising solution to overcome the von Neumann bottleneck. Due to non-idealities like cell variability, RRAM crossbars are often…

Sequence alignment is a fundamental process in computational biology which identifies regions of similarity in biological sequences. With the exponential growth in the volume of data in bioinformatics databases, the time, processing power,…

Hardware Architecture · Computer Science 2025-07-31 Nasrin Akbari , Mehdi Modarressi , Alireza Khadem

With the rapid growth of deep neural networks (DNNs), compute-in-memory (CIM) has emerged as a promising energy-efficient paradigm for accelerating multiply-and-accumulate (MAC) operations. Yet, current CIM architectures are largely limited…

Hardware Architecture · Computer Science 2026-04-16 Subhradip Chakraborty , Ankur Singh , Akhilesh R. Jaiswal

Similarity search is a key to a variety of applications including content-based search for images and video, recommendation systems, data deduplication, natural language processing, computer vision, databases, computational biology, and…

Distributed, Parallel, and Cluster Computing · Computer Science 2017-07-11 Vincent T. Lee , Amrita Mazumdar , Carlo C. del Mundo , Armin Alaghi , Luis Ceze , Mark Oskin

Simulation plays a central role in scientific discovery. In many applications, the bottleneck is no longer running a simulator; it is choosing among large families of plausible simulators, each corresponding to different forward…

Genome sequence analysis has enabled significant advancements in medical and scientific areas such as personalized medicine, outbreak tracing, and the understanding of evolution. Unfortunately, it is currently bottlenecked by the…

Analog Compute-in-Memory (CiM) accelerators are increasingly recognized for their efficiency in accelerating Deep Neural Networks (DNN). However, their dependence on Analog-to-Digital Converters (ADCs) for accumulating partial sums from…

Hardware Architecture · Computer Science 2024-03-21 Shubham Negi , Utkarsh Saxena , Deepika Sharma , Kaushik Roy

Approximate computing emerges as a promising approach to enhance the efficiency of compute-in-memory (CiM) systems in deep neural network processing. However, traditional approximate techniques often significantly trade off accuracy for…

Hardware Architecture · Computer Science 2024-09-02 Wenlun Zhang , Shimpei Ando , Yung-Chin Chen , Satomi Miyagi , Shinya Takamaeda-Yamazaki , Kentaro Yoshioka

Histopathological image classification is an important task in medical image analysis. Recent approaches generally rely on weakly supervised learning due to the ease of acquiring case-level labels from pathology reports. However,…

Computer Vision and Pattern Recognition · Computer Science 2024-11-14 Bodong Zhang , Hamid Manoochehri , Man Minh Ho , Fahimeh Fooladgar , Yosep Chong , Beatrice S. Knudsen , Deepika Sirohi , Tolga Tasdizen

Computing-in-memory (CIM) architectures demonstrate superior performance over traditional architectures. To unleash the potential of CIM accelerators, many compilation methods have been proposed, focusing on application scheduling…

Hardware Architecture · Computer Science 2025-02-25 Shixin Zhao , Yuming Li , Bing Li , Yintao He , Mengdi Wang , Yinhe Han , Ying Wang

Memristive nanodevices offer new frontiers for computing systems that unite arithmetic and memory operations on-chip. Here, we explore the integration of electrochemical metallization cell (ECM) nanodevices with tunable filamentary…

Neural and Evolutionary Computing · Computer Science 2016-06-28 Christopher H. Bennett , Selina La Barbera , Adrien F. Vincent , Fabien Alibart , Damien Querlioz

Genome sequence analysis plays a pivotal role in enabling many medical and scientific advancements in personalized medicine, outbreak tracing, and forensics. However, the analysis of genome sequencing data is currently bottlenecked by the…

Hardware Architecture · Computer Science 2021-11-04 Damla Senol Cali

Computing-in-Memory architectures based on non-volatile emerging memories have demonstrated great potential for deep neural network (DNN) acceleration thanks to their high energy efficiency. However, these emerging devices can suffer from…

Machine Learning · Computer Science 2022-10-10 Zheyu Yan , Xiaobo Sharon Hu , Yiyu Shi

Stochastic computing (SC) offers hardware simplicity but suffers from low throughput, while high-throughput Digital Computing-in-Memory (DCIM) is bottlenecked by costly adder logic for matrix-vector multiplication (MVM). To address this…

Hardware Architecture · Computer Science 2026-01-13 Kunming Shao , Liang Zhao , Jiangnan Yu , Zhipeng Liao , Xiaomeng Wang , Yi Zou , Tim Kwang-Ting Cheng , Chi-Ying Tsui

Compute-In-Memory (CIM) systems, particularly those utilizing ReRAM and memristive technologies, offer a promising path toward energy-efficient neural network computation. However, conventional quantization and compression techniques often…

Hardware Architecture · Computer Science 2025-12-23 Guan-Cheng Chen , Chieh-Lin Tsai , Pei-Hsuan Tsai , Yuan-Hao Chang

Deep Neural Networks (DNNs) continue to grow in complexity with Large Language Models (LLMs) incorporating vast numbers of parameters. Handling these parameters efficiently in traditional accelerators is limited by data-transmission…

Hardware Architecture · Computer Science 2025-12-02 Swastik Bhattacharya , Sanjay Das , Anand Menon , Shamik Kundu , Arnab Raha , Kanad Basu

This paper presents a new, parallel implementation of clustering and demonstrates its utility in greatly speeding up the process of identifying homologous proteins. Clustering is a technique to reduce the number of comparison needed to find…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-08-29 Stuart Byma , Akash Dhasade , Adrian Altenhoff , Christophe Dessimoz , James R. Larus
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