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Phase is an intrinsic property of light, and thus a crucial parameter across numerous applications in modern optics. Various methods exist for measuring the phase of light, each presenting challenges and limitations-from the mechanical…

High-throughput label-free measurements of the optical and mechanical properties of single microparticles play an important role in biological research, drug development, and related large population assays. Mechanical detection techniques…

Instrumentation and Detectors · Physics 2018-12-05 Kewen Han , Jeewon Suh , Gaurav Bahl

Detection and characterization of individual nano-scale particles, virions, and pathogens are of paramount importance to human health, homeland security, diagnostic and environmental monitoring[1]. There is a strong demand for…

Optics · Physics 2011-07-06 Lina He , Sahin Kaya Ozdemir , Jiangang Zhu , Woosung Kim , Lan Yang

Free electron beams such as those employed in electron microscopes have evolved into powerful tools to investigate photonic nanostructures with an unrivaled combination of spatial and spectral precision through the analysis of electron…

Quantum Physics · Physics 2021-04-22 F. Javier García de Abajo , Valerio Di Giulio

We introduce an approach for performing spectrally resolved electron microscopy without the need for an electron spectrometer. The method involves an electron beam prepared as a coherent superposition of multiple paths, one of which passes…

Materials Science · Physics 2025-04-24 F. Javier García de Abajo , Cruz I. Velasco

Nonlinear interferometry with entangled photons allows for characterizing a sample without detecting the photons interacting with it. This method enables highly sensitive optical sensing in the wavelength regions where efficient detectors…

Optics · Physics 2025-08-11 Kazuki Hashimoto , Dmitri B. Horoshko , Maria V. Chekhova

Next-generation optoelectronic devices and photonic circuitry will have to incorporate on-chip compatible nanolaser sources. Semiconductor nanowire lasers have emerged as strong candidates for integrated systems with applications ranging…

We re-examine real-time holography for all-optical structuring of light and optical computation using a contemporary material: a subwavelength-thick, spatially unstructured film of indium tin oxide (ITO). When excited by spatially…

We propose a nonlinear imaging scheme with undetected photons that overcomes the diffraction limit by transferring near-field information at one wavelength to far-field information of a correlated photon with a different wavelength…

Quantum Physics · Physics 2022-05-11 Elkin A. Santos , Thomas Pertsch , Frank Setzpfandt , Sina Saravi

To effectively apply passive speckle reduction methods, it is essential to use an illumination system that maximally exploits the non-ideal temporal coherence and angular diversity (spatial coherence reduction) of laser light. This study…

Optics · Physics 2025-04-28 A. Lapchuk , O. Prygun , D. Manko , I. Gorbov , Y. Morozov

Silicon photoluminescence and lasing have been critical issues to breakthrough bottlenecks in the understanding of luminescence mechanisms. Unfortunately, long-standing disputes about the exciton recombination mechanism and fluorescence…

Mesoscale and Nanoscale Physics · Physics 2022-11-01 Feilong Wang , Qiongrong Ou , Shuyu Zhang

We propose an approach to far-field optical imaging beyond the diffraction limit. The proposed system allows image magnification, is robust with respect to material losses and can be fabricated by adapting existing metamaterial technologies…

Optics · Physics 2009-11-13 Zubin Jacob , Leonid V. Alekseyev , Evgenii Narimanov

Super-resolution Structured Illumination Microscopy (SR-SIM) enables fluorescence microscopy beyond the diffraction limit at high frame rates. Compared to other super-resolution microscopy techniques, the low photon fluence used in SR-SIM…

The ability to tailor laser light on a chip using integrated photonics has allowed for extensive control over fundamental light-matter interactions in manifold quantum systems including atoms, trapped ions, quantum dots, and defect centers.…

Label-free optical microscopy through absorption or scattering spectroscopy provides fundamental insights across biology and materials science, yet its sensitivity remains fundamentally limited by photon shot noise. While recent…

Super-resolution effects in optical and fluorescence biological systems are analyzed and their relations with uncertainty relations are discussed. Super-resolutions obtained in the optical systems, including especially NSOM, SIM and…

Optics · Physics 2015-06-12 Yacob Ben-Aryeh

A novel non-invasive microscopy technique for imaging and sizing of folded DNA molecules with the use of photovoltaic tweezers and phase-sensitive detection is elaborated and realized. This novel method is compared with the state-of-the-art…

Atomic Physics · Physics 2025-02-27 Lusine Tsarukyan , Anahit Badalyan , Rafael Drampyan

Fluorescence lifetime imaging microscopy (FLIM) is a powerful quantitative technique that provides metabolic and molecular contrast, offering strong translational potential for label-free, real-time diagnostics. However, its clinical…

Computer Vision and Pattern Recognition · Computer Science 2025-12-19 Paloma Casteleiro Costa , Parnian Ghapandar Kashani , Xuhui Liu , Alexander Chen , Ary Portes , Julien Bec , Laura Marcu , Aydogan Ozcan

Nonlinear optical microscopy allows rapid high-resolution microscopy with image contrast generated from intrinsic properties of the sample. Established modalities such as multiphoton excited fluorescence and second/third-harmonic generation…