Related papers: Future Developments in Charged Particle Therapy: I…
Intensity-modulated proton therapy (IMPT) offers superior dose conformity with reduced exposure to surrounding healthy tissues compared to conventional photon therapy. Improving IMPT delivery efficiency reduces motion-related uncertainties,…
Laser-driven proton sources have long been developed with an eye on their potential for medical application to radiation therapy. These sources are compact, versatile, and show peculiar characteristics such as extreme instantaneous dose…
Access to high-energy particle beams is key for testing high-energy physics (HEP) instruments. Accelerators for cancer treatment can serve as such a testing ground. However, HEP instrument tests typically require particle fluxes…
This paper describes the dose delivery system used at the Centro Nazionale di Adroterapia Oncologica (CNAO) for ion beam modulated scanning radiotherapy. CNAO Foundation, INFN and University of Torino have developed and commissioned a Dose…
This paper presents a novel procedure for energy management system (EMS) that can utilize the flexibility in transmission network in a practical way. With the proposed enhanced EMS procedure, the reliability benefits that are provided by…
Purpose: The FLASH effect, which reduces the radiosensitivity of healthy tissue while maintaining tumor control at high dose rates, has shown potential for improving radiation therapy. Conformal FLASH proton therapy involves advanced…
The long-term efficacy of targeted therapeutics for cancer treatment can be significantly limited by the type of therapy and development of drug resistance, inter alia. Experimental studies indicate that the factors enhancing acquisition of…
Resonant beam charging (RBC) can realize wireless power transfer (WPT) from a transmitter to multiple receivers via resonant beams. The adaptive RBC (ARBC) can effectively improve its energy utilization. In order to support multi-user WPT…
Plasma acceleration has emerged as a promising technology for future particle accelerators, particularly linear colliders. Significant progress has been made in recent decades toward high-efficiency and high-quality acceleration of…
Proton beams generated from laser acceleration show merit for their unique spatial (micron-size) and temporal (picosecond) properties, which make them desirable for many potential applications. However, the large energy spread and…
Purpose: To present the performance of a multi-point plastic scintillation detector (mPSD) as a tool in vivo dosimetry in brachytherapy. Methods: A previously optimized three-point sensor system was used for in vivo HDR brachytherapy…
Not long after the laser was invented, it has been marked as a candidate source of strong, high-frequency electromagnetic radiation for acceleration of particles. Indeed, while the complex particle accelerator facilities today are an…
We propose a fast beam orientation selection method, based on deep neural networks (DNN), capable of developing a plan comparable to those by the state-of-the-art column generation method. The novelty of Our model lies in its supervised…
In planning for the Phase II upgrades of CMS and ATLAS major considerations are: 1)being able to deal with degradation of tracking and calorimetry up to the radiation doses to be expected with an integrated luminosity of 3000 $fb^{-1}$ and…
The increasing utilization of charged particle beams for therapeutic purposes requires designing novel detector systems which shall be capable of assessing radiation quality for a diversity of ion species. It is shown that the pattern of…
Controlled drug delivery (CDD), the controlled release and delivery of therapeutic drugs inside the human body, is a promising approach to increase the efficacy of drug administration and reduce harmful side effects to the body. CDD has…
Proton beam therapy can potentially offer improved treatment for cancers of the head and neck and in paediatric patients. There has been a sharp uptake of proton beam therapy in recent years as improved delivery techniques and patient…
Conceptualization, theory, method developments and implementations are always of great importance and an interesting task to explore a new dimension in science and technology, which is highly solicited for various functional-driven…
The advent of ultra-high dose rate irradiation, known as FLASH radiation therapy, has shown promising potential in reducing toxicity while maintaining tumor control. However, the clinical translation of these benefits necessitates efficient…
Collinear high-gradient ${\cal O} (GV/m)$ beam-driven wakefield methods for charged-particle acceleration could be critical to the realization of compact, cost-efficient, accelerators, e.g., in support of TeV-scale lepton colliders or…