Related papers: Future Developments in Charged Particle Therapy: I…
Purpose: The purpose of this work was to provide a flexible platform for FLASH research with protons by adapting a former clinical pencil beam scanning gantry to irradiations with ultrahigh dose rates. Methods: PSI Gantry 1 treated patients…
Purpose: To determine whether alternative HDR prostate brachytherapy catheter patterns can result in improved dose distributions while providing better access and reducing trauma. Methods: Prostate HDR brachytherapy uses a grid of parallel…
Important recent advances in transmission electron microscopy instrumentation and capabilities have made it indispensable for atomic-scale materials characterization. At the same time, the availability of two-dimensional materials has…
Staging laser wake-field acceleration is considered as a necessary technique for developing full-optical jitter-free electron accelerators. Splitting of the acceleration length into several technical parts with their lengths smaller than…
Progress on the Intensity Frontier of high energy physics critically depends on record high intensity charged particles accelerators. Beams in such machines become operationally limited by coherent beam instabilities, particularly enhanced…
In observational studies, weighting methods that directly optimize the balance between treatment and covariates have received much attention lately; however these have mainly focused on binary treatments. Inspired by domain adaptation, we…
Laser-wakefield acceleration is a promising technique for the next generation of ultra-compact, high-energy particle accelerators. However, for a meaningful use of laser-driven particle beams it is necessary that they present a high degree…
Carbon-ion radiotherapy (CIRT) is generally evaluated with the dose weighted by relative biological effectiveness (RBE), while the radiation quality varying in the body of each patient is ignored for lack of such distribution. In this…
Cone-beam computed tomography (CBCT) is an imaging modality widely used in head and neck diagnostics due to its accessibility and lower radiation dose. However, its relatively long acquisition times make it susceptible to patient motion,…
Wakefield accelerators are under development in many laboratories worldwide. They bring the promise of a high accelerating gradient, orders of magnitude higher than current machines. The reduction in the overall length of the accelerators…
The development of a digital twin (DT) framework for fast online adaptive proton therapy planning in prostate stereotactic body radiation therapy (SBRT) with dominant intraprostatic lesion (DIL) boost represents a significant advancement in…
Adaptive Radiotherapy (ART) is an emerging technique for treating cancer patients which facilitates higher delivery accuracy and has the potential to reduce toxicity. However, ART is also resource-intensive, requiring extra human and…
This study conceptualizes electronic dose to water, which is the radiation energy imparted to a unit mass of water by electronic interactions. The new dosimetry framework excludes nuclear interactions and consequently associated corrections…
High-power laser technologies are essential in precision manufacturing, defense, and scientific research, where accurate control of the beam profile is paramount. Although several beam-shaping methods exist, they often face implementation…
In this first paper of a two-paper series, we present a method for optimizing the dynamic delivery of fluence maps in radiation therapy. For a given fluence map and a given delivery time, the optimization of the leaf trajectories of a…
Ultra-reliable low-latency Vehicle-to-Everything (V2X) communications are needed to meet the extreme requirements of enhanced driving applications. Millimeter-Wave (24.25-52.6 GHz) or sub-THz (>100 GHz) V2X communications are a viable…
Today, intensity-modulated radiation therapy (IMRT) is one of the methods used to treat brain tumors. In conventional treatment planning methods, after identifying planning target volume (PTV), and organs at risk (OARs), and determining the…
The widespread diffusion of precision radiotherapy techniques, geared toward the release of larger dose gradients in shorter time frames, is leading to new challenges in dosimetry. Accurate dose measurements are essential to check for beam…
Positron Emission Tomography (PET) and Computed Tomography (CT) are essential for diagnosing, staging, and monitoring various diseases, particularly cancer. Despite their importance, the use of PET/CT systems is limited by the necessity for…
Temporally modulated pulsed radiotherapy (TMPRT) delivers conventional fraction doses of radiation using temporally separated pulses of low doses (<30 cGy) yielding fraction-effective dose rates of around 6.7 cGy/min with the goal to…