Related papers: Future Developments in Charged Particle Therapy: I…
The radiotherapy of malignant diseases has reached much progress during the past decade. Thus, intensity modulated radiation therapy (IMRT) and VMAT (Rapidarc) now belong to the standard modalities of tumor treatment with high energy…
A new method of controllable injection to generate high quality electron bunches in the nonlinear blowout regime driven by electron beams is proposed and demonstrated using particle-in-cell simulations. Injection is facilitated by…
Efficient transport of high-current negative ion beams is critical for accurate plasma potential diagnostics using heavy-ion beam probe (HIBP) systems in magnetically confined fusion plasmas. However, strong space-charge effects often…
This study explores nanoparticle-assisted electron injection as a method for controlling beam charge in laser wakefield acceleration through particle-in-cell simulations. We systematically investigate how the material (Li through Au) and…
Artificial intelligence (AI) is entering medical imaging, mainly enhancing image reconstruction. Nevertheless, improvements throughout the entire processing, from signal detection to computation, potentially offer significant benefits. This…
Ion beam has been used in cancer treatment, and has a unique preferable feature to deposit its main energy inside a human body so that cancer cell could be killed by the ion beam. However, conventional ion accelerator tends to be huge in…
Purpose: Accurate prediction of beam delivery time (BDT) is essential for operational efficiency, 4D dose calculations, and advanced proton therapy techniques. Despite its importance, no machine-specific BDT model exists for Mevion systems.…
Purpose: This study explores the feasibility of dose-escalated proton beam therapy (dPBT) for Locally Advanced Pancreatic Cancer (LAPC) patients by modeling common patient scenarios using current clinically-adopted practices. Methods: Five…
Laser-plasma accelerators represent a promising technology for future compact accelerating systems, enabling the acceleration of tens of pC to above $1\,$GeV over just a few centimeters. Nonetheless, these devices currently lack the…
Accelerating particles to high energies in plasma wakefields is considered to be a promising technique with good energy efficiency and high gradient. While important progress has been made in plasma-based electron acceleration, positron…
Despite the fact that the first-order beam dynamics models allow an approximated evaluation of the beam properties, their contribution is essential during the conceptual design of an accelerator or beamline. However, during the…
Dual-energy computed tomography (DECT) is a promising technology that has shown a number of clinical advantages over conventional X-ray CT, such as improved material identification, artifact suppression, etc. For proton therapy treatment…
FLASH radiotherapy necessitates the development of advanced Quality Assurance methods and detectors for accurate and online monitoring of the radiation field. This study introduces enhanced time-resolution detection systems and methods…
A new variant of the pencil-beam (PB) algorithm for dose distribution calculation for radiotherapy with protons and heavier ions, the grid-dose spreading (GDS) algorithm, is proposed. The GDS algorithm is intrinsically faster than…
Proton (and ion) cancer therapy has proven to be an extremely effective even supe-rior method of treatment for some tumors 1-4. A major problem, however, lies in the cost of the particle accelerator facilities; high procurement costs…
In robotic radiation therapy, high-energy photon beams from different directions are directed at a target within the patient. Target motion can be tracked by robotic ultrasound and then compensated by synchronous beam motion. However,…
Heterogeneous treatment effect estimation in high-stakes applications demands models that simultaneously optimize precision, interpretability, and calibration. Many existing tree-based causal inference techniques, however, exhibit high…
Time over dynamic threshold (TODT) method, proposed in our previous work, has been successfully used for nuclear pulse charge measurement in PET detectors. It has advantages of strict linearity, large dynamic range, and better energy…
Diffusing Alpha-emitters Radiation Therapy (DaRT) is a new method for treating solid tumors using alpha particles. Unlike conventional radiotherapy, where the physical models for dose calculations are known and routinely used, for DaRT a…
In accelerators, ion beams are often accelerated using electrostatic accelerating tubes. This paper reports on a method to improve the beam transport efficiency without adding new components to the beam transport system. High beam currents…