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Acoustic-resolution photoacoustic microscopy (AR-PAM) is a promising tool for microvascular imaging. In the focal region, resolution of AR-PAM is determined by the ultrasound transducer and ultimately limited by acoustic diffraction. In the…

Image and Video Processing · Electrical Eng. & Systems 2021-11-22 Fei Feng , Siqi Liang , Sung-Liang Chen

Photo-acoustic tomography is a coupled-physics (hybrid) medical imaging modality that aims to reconstruct optical parameters in biological tissues from ultrasound measurements. As propagating light gets partially absorbed, the resulting…

Analysis of PDEs · Mathematics 2020-01-08 Guillaume Bal , Adrian Kirkeby

Spreading depolarization (SD) is a self-propagating wave of near-complete neuronal depolarization that is abundant in a wide range of neurological conditions, including stroke. SD was only recently documented in humans and is now considered…

Motion, e.g., due to patient movement or improper device calibration, is inevitable in many imaging modalities such as photoacoustic tomography (PAT) by a rotating system and can lead to undesirable motion artifacts in image…

Numerical Analysis · Mathematics 2016-09-28 Julianne Chung , Linh Nguyen

Photon attenuation and scatter are the two main physical factors affecting the diagnostic quality of SPECT in its applications in brain imaging. In this work, we present a novel Bayesian Optimization approach for Attenuation Correction…

Medical Physics · Physics 2021-09-27 Loizos Koutsantonis , Ayman Makki , Tiago Carneiro , Emmanuel Kieffer , Pascal Bouvry

Spectroscopic photoacoustic (sPA) imaging can potentially estimate blood oxygenation saturation (sO2) in vivo noninvasively. However, quantitatively accurate results require accurate optical fluence estimates. Robust modeling in…

Image and Video Processing · Electrical Eng. & Systems 2025-12-18 Ruibo Shang , Sidhartha Jandhyala , Yujia Wu , Kevin Hoffer-Hawlik , Austin Van Namen , Matthew O'Donnell , Geoffrey P. Luke

Photoacoustic tomography (PAT) is a novel and promising technology in hybrid medical imaging that involves generating acoustic waves in the object of interest by stimulating electromagnetic energy. The acoustic wave is measured outside the…

Numerical Analysis · Mathematics 2022-08-24 Minam Moon , Injo Hur , Sunghwan Moon

Optical coherence tomography (OCT) and photoacoustic tomography (PAT) are emerging non-invasive biological and medical imaging techniques. It is a recent trend in experimental science to design experiments that perform PAT and OCT imaging…

Analysis of PDEs · Mathematics 2016-04-19 Peter Elbau , Leonidas Mindrinos , Otmar Scherzer

Image reconstruction is an essential step of every medical imaging method, including Photoacoustic Tomography (PAT), which is a promising modality of imaging, that unites the benefits of both ultrasound and optical imaging methods.…

Image and Video Processing · Electrical Eng. & Systems 2024-04-26 Hesam Hakimnejad , Zohreh Azimifar , Narjes Goshtasbi

Photo-Acoustic Tomography (PAT) can reconstruct a distribution of optical absorbers acting as instantaneous sound sources in subcutaneous microvasculature of a human breast. Adjoint methods for PAT, typically Time-Reversal (TR) and…

Numerical Analysis · Mathematics 2018-06-25 Hongxiang Lin , Takashi Azuma , Mehmet Burcin Unlu , Shu Takagi

Acoustic-Resolution Photoacoustic Microscopy (AR-PAM) is promising for subcutaneous vascular imaging, but its spatial resolution is constrained by the Point Spread Function (PSF). Traditional deconvolution methods like Richardson-Lucy and…

Computer Vision and Pattern Recognition · Computer Science 2024-10-29 Youshen Xiao , Sheng Liao , Xuanyang Tian , Fan Zhang , Xinlong Dong , Yunhui Jiang , Xiyu Chen , Ruixi Sun , Yuyao Zhang , Fei Gao

Multi-spectral optoacoustic tomography (MSOT) is an emerging optical imaging method providing multiplex molecular and functional information from the rodent brain. It can be greatly augmented by magnetic resonance imaging (MRI) that offers…

Image and Video Processing · Electrical Eng. & Systems 2021-09-07 Yexing Hu , Berkan Lafci , Artur Luzgin , Hao Wang , Jan Klohs , Xose Luis Dean-Ben , Ruiqing Ni , Daniel Razansky , Wuwei Ren

Conventional photoacoustic imaging may suffer from the limited view and bandwidth of ultrasound transducers. A deep learning approach is proposed to handle these problems and is demonstrated both in simulations and in experiments on a…

Image and Video Processing · Electrical Eng. & Systems 2020-11-19 Guillaume Godefroy , Bastien Arnal , Emmanuel Bossy

In many clinical conditions, such as head trauma, stroke, and low cardiac output states, the brain is at risk for hypoxic-ischemic injury. The metabolic rate and oxygen consumption of the brain are reflected in internal jugular venous…

Deep-learning-based super-resolution photoacoustic angiography (PAA) is a powerful tool that restores blood vessel images from under-sampled images to facilitate disease diagnosis. Nonetheless, due to the scarcity of training samples, PAA…

Image and Video Processing · Electrical Eng. & Systems 2023-05-03 Yuanzheng Ma , Wangting Zhou , Rui Ma , Sihua Yang , Yansong Tang , Xun Guan

Photoacoustic (PA) computed tomography (PACT) reconstructs the initial pressure distribution from raw PA signals. The standard reconstruction of medical image could cause the artifacts due to interferences or ill-posed setup. Recently, deep…

Computer Vision and Pattern Recognition · Computer Science 2021-05-26 Hengrong Lan , Changchun Yang , Fei Gao

Photoacoustic imaging (PAI) and ultrasound imaging (USI) are important biomedical imaging techniques, due to their unique and complementary advantages in tissue's structure and function visualization. In this Letter, we proposed a coaxial…

Medical Physics · Physics 2024-11-12 Yunhui Jiang , Fan Zhang , Yuwei Zheng , Ruixi Sun , Fei Gao

Acoustic holograms are the keystone of modern acoustics. It encodes three-dimensional acoustic fields in two dimensions, and its quality determine the performance of acoustic systems. Optimisation methods that control only the phase of an…

Sound · Computer Science 2021-06-17 Tatsuki Fushimi , Kenta Yamamoto , Yoichi Ochiai

Photoacoustic image (PAI) quality improvement using a low frequency piezoelectric micromachined ultrasound transducer (PMUT) having the fundamental resonant frequency 1 MHz is being reported. Specifically, three different methods are…

Instrumentation and Detectors · Physics 2022-12-01 Kaustav Roy , Arijit Paramanik , Souradip Paul , Akshay Kalyan , Eshani Sarkar , Anuj Ashok , Rudra Pratap , M Suheshkumar Singh

Dual-energy computed tomography (DECT) has shown great potential and promising applications in advanced imaging fields for its capabilities of material decomposition. However, image reconstructions and decompositions under sparse views…

Medical Physics · Physics 2016-08-01 Lei Li , Ailong Cai , Linyuan Wang , Bin Yan , Hanming Zhang , Zhizhong Zheng , Wenkun Zhang , Wanli Lu , Guoen Hu