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Automated segmentation of anatomical sub-regions with high precision has become a necessity to enable the quantification and characterization of cells/ tissues in histology images. Currently, a machine learning model to analyze…

Image and Video Processing · Electrical Eng. & Systems 2023-06-05 Hosein Barzekar , Hai Ngu , Han Hui Lin , Mohsen Hejrati , Steven Ray Valdespino , Sarah Chu , Baris Bingol , Somaye Hashemifar , Soumitra Ghosh

Medical images used in clinical practice are heterogeneous and not the same quality as scans studied in academic research. Preprocessing breaks down in extreme cases when anatomy, artifacts, or imaging parameters are unusual or protocols…

Image and Video Processing · Electrical Eng. & Systems 2022-08-31 Mostafa Mehdipour Ghazi , Mads Nielsen

In photoacoustic tomography (PAT) with flat sensor, we routinely encounter two types of limited data. The first is due to using a finite sensor and is especially perceptible if the region of interest is large relative to the sensor or…

Image and Video Processing · Electrical Eng. & Systems 2022-11-08 Bolin Pan , Marta M. Betcke

Photoacoustic fluctuation imaging, which exploits randomness in photoacoustic generation, provides enhanced images in terms of resolution and visibility, as compared to conventional photoacoustic images. While a few experimental…

Optics · Physics 2020-11-19 Sergey Vilov , Guillaume Godefroy , Bastien Arnal , Emmanuel Bossy

Machine learning has been developed dramatically and witnessed a lot of applications in various fields over the past few years. This boom originated in 2009, when a new model emerged, that is, the deep artificial neural network, which began…

Computer Vision and Pattern Recognition · Computer Science 2020-12-03 Changchun Yang , Hengrong Lan , Feng Gao , Fei Gao

Photoacoustic tomography is a contrast agent-free imaging technique capable of visualizing blood vessels and tumor-associated vascularization in breast tissue. While sophisticated breast imaging systems have been recently developed, there…

Herein we report the first in-human transcranial imaging of brain function using photoacoustic computed tomography. Functional responses to benchmark motor tasks were imaged on both the skull-less and the skull-intact hemispheres of a…

Virtual Imaging Trials (VIT) offer a cost-effective and scalable approach for evaluating medical imaging technologies. Computational phantoms, which mimic real patient anatomy and physiology, play a central role in VITs. However, the…

Quantitative photo-acoustic tomography (QPAT) seeks to reconstruct a distribution of optical attenuation coefficients inside a sample from a set of time series of pressure data that is measured outside the sample. The associated inverse…

Optimization and Control · Mathematics 2019-09-04 Ashkan Javaherian , Sean Holman

As a hybrid imaging technology, photoacoustic microscopy (PAM) imaging suffers from noise due to the maximum permissible exposure of laser intensity, attenuation of ultrasound in the tissue, and the inherent noise of the transducer.…

Image and Video Processing · Electrical Eng. & Systems 2022-01-13 Da He , Jiasheng Zhou , Xiaoyu Shang , Jiajia Luo , Sung-Liang Chen

In most photoacoustic (PA) measurements, variations in speed-of-sound (SOS) of the subject are neglected under the assumption of acoustic homogeneity. Biological tissue with spatially heterogeneous SOS cannot be accurately reconstructed…

Photoacoustic imaging and sensing have been studied extensively to probe the optical absorption of biological tissue in multiple scales ranging from large organs to small molecules. However, its elastic oscillation characterization is…

Optics · Physics 2015-09-21 Fei Gao , Xiaohua Feng , Yuanjin Zheng

Photoacoustic imaging (PAI) is an emerging non-invasive imaging modality combining the advantages of deep ultrasound penetration and high optical contrast. Image reconstruction is an essential topic in PAI, which is unfortunately an…

Image and Video Processing · Electrical Eng. & Systems 2019-08-06 Hengrong Lan , Daohuai Jiang , Changchun Yang , Fei Gao

In this paper we consider the problem of image reconstruction in optoacoustic tomography. In particular, we devise a deep neural architecture that can explicitly take into account the band-frequency information contained in the sinogram.…

Image and Video Processing · Electrical Eng. & Systems 2023-01-25 Martin G. Gonzalez , Matias Vera , Leonardo Rey Vega

Photoacoustic imaging is an emerging technology based on the photoacoustic effect that has developed rapidly in recent years. It combines the high contrast of optical imaging and the high penetration and high resolution of acoustic imaging.…

Optoacoustic tomography (OAT), also known as photoacoustic tomography, is an emerging computed biomedical imaging modality that exploits optical contrast and ultrasonic detection principles. Iterative image reconstruction algorithms that…

Medical Physics · Physics 2016-11-17 Kun Wang , Robert W Schoonover , Richard Su , Alexander Oraevsky , Mark A Anastasio

Photoacoustic tomography (PAT) is an emerging imaging modality that combines the complementary strengths of optical contrast and ultrasonic resolution. A central task is image reconstruction, where measured acoustic signals are used to…

Computer Vision and Pattern Recognition · Computer Science 2026-04-20 Markus Haltmeier , Nadja Gruber , Gyeongha Hwang

Photoacoustic (PA) imaging technology combines the advantages of optical imaging and ultrasound imaging, showing great potential in biomedical applications. Many preclinical studies and clinical applications urgently require fast,…

Image and Video Processing · Electrical Eng. & Systems 2024-08-13 Yuwei Zheng , Zijian Gao , Yuting Shen , Jiadong Zhang , Daohuai Jiang , Fengyu Liu , Feng Gao , Fei Gao

Objectives: Computerized phantoms play an essential role in various applications of medical imaging research. Although the existing computerized phantoms can model anatomical variations through organ and phantom scaling, this does not…

Image and Video Processing · Electrical Eng. & Systems 2021-04-20 Junyu Chen , Ye Li , Yong Du , Eric C. Frey

Photoacoustic Computed Tomography (PACT) is a major configuration of photoacoustic imaging, a hybrid noninvasive modality for both functional and molecular imaging. PACT has rapidly gained importance in the field of biomedical imaging due…

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