Herein we report the first in-human transcranial imaging of brain function using photoacoustic computed tomography. Functional responses to benchmark motor tasks were imaged on both the skull-less and the skull-intact hemispheres of a hemicraniectomy patient. The observed brain responses in these preliminary results demonstrate the potential of photoacoustic computed tomography for achieving transcranial functional imaging.
@article{arxiv.2206.00248,
title = {Transcranial photoacoustic computed tomography of human brain function},
author = {Yang Zhang and Shuai Na and Karteekeya Sastry and Jonathan J. Russin and Peng Hu and Li Lin and Xin Tong and Kay B. Jann and Danny J. Wang and Charles Y. Liu and Lihong V. Wang},
journal= {arXiv preprint arXiv:2206.00248},
year = {2022}
}