Related papers: A novel range telescope concept for proton CT

A Geant4 based simulation platform of the Holland Proton Therapy Centre (HollandPTC, Netherlands) R&D beamline (G4HPTC-R&D) was developed to enable the planning, optimisation and advanced dosimetry for radiobiological studies. It…

The design of the new space-based gamma-ray telescope GAMMA-400 is presented. GAMMA-400 is optimized for the energy 100 GeV with the best parameters: the angular resolution ~0.01 deg, the energy resolution ~1%, and the proton rejection…

MedAustron is a synchrotron-based particle therapy centre located in Wiener Neustadt, Austria. It features three irradiation rooms for particle therapy, where proton beams with energies up to 252.7 MeV and carbon ions of up to 402.8 MeV/u…

This article proposes a new method to measure the proton detector efficiency for use in "beam" determinations of the free neutron lifetime. There is currently a 4{\sigma} disagreement between the "beam" and "storage" methods of measuring…

Objective: The aim of this work is to investigate the feasibility of the Jagiellonian Positron Emission Tomography (J-PET) scanner for intra-treatment proton beam range monitoring. Approach: The Monte Carlo simulation studies with GATE and…

Objective: To develop and validate an independent Monet Carlo dose calculation engine to support for software verification of treatment planning systems and quality assurance workflow. Method: GATE Monte Carlo toolkit was employed to…

Protontherapy is hadrontherapy fastest-growing modality and a pillar in the battle against cancer. Hadrontherapy superiority lies in its inverted depth-dose profile, hence tumour-confined irradiation. Protons, however, lack distinct…

We propose an oAPT workflow that incorporates all these functionalities and validate its clinical implementation feasibility with prostate patients. AI-based auto-segmentation tool AccuContourTM (Manteia, Xiamen, China) was seamlessly…

Given the sensitivity of proton therapy to anatomical variations, this cancer treatment modality is expected to benefit greatly from integration with magnetic resonance (MR) imaging. One of the obstacles hindering such an integration are…

The HEGRA system of 4 Imaging Atmospheric Cherenkov Telescopes (IACTs) has been used to determine the flux and the spectrum of cosmic ray protons over a limited energy range around 1.5 TeV. Although the IACT system is designed for the…

In recent years, volumetric modulated arc therapy (VMAT) has been becoming a more and more important radiation technique widely used in clinical application for cancer treatment. One of the key problems in VMAT is treatment plan…

Dual-energy CT (DECT) has been widely investigated to generate more informative and more accurate images in the past decades. For example, Dual-Energy Alternating Minimization (DEAM) algorithm achieves sub-percentage uncertainty in…

Objective: Real-time adaptive proton range verification systems based on produced neutrons require accurate information on their non-isotropic momentum distributions within short times, for which Monte Carlo (MC) methods are too…

Treatment delivery is largely determined by capabilities of the beam delivery system (BDS), where faster delivery can have many potential benefits including improved dosimetric quality, utility, cost effectiveness, patient throughput and…

A neutron time projection chamber can locate the approximate direction of a neutron hot spot with high efficiency and a 4{\pi} field of view. The angular resolution can be significantly improved by adding several plastic scintillation…

Purpose: Proton therapy provides superior dose conformity compared to photon therapy, but its treatment planning is challenged by sensitivity to anatomical changes, setup/range uncertainties, and computational complexity. This review…

We report on an hybrid in-beam PET and prompt-gamma Compton imaging system aimed at quasi real-time ion-range verification in proton-therapy treatments. Proof-of-concept experiments were carried out at the radiobiology beam line of the CNA…

Dual-energy computed tomography (DECT) is a promising technology that has shown a number of clinical advantages over conventional X-ray CT, such as improved material identification, artifact suppression, etc. For proton therapy treatment…

Carbon ion therapy is one of the most advanced forms of radiotherapy, promising improved efficacy against resistant cancers. However, the high precision offered by the carbon ion Bragg peak requires precise knowledge of the beam range…

The proton radiography diagnostic is widely used in laser-plasma experiments to make magnetic field measurements. Recent developments in analysis have enabled quantitative reconstruction of path-integrated magnetic field values, but making…