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The beam transport system between accelerator and patient treatment location in a particle therapy facility is described. After some general layout aspects the major beam handling tasks of this system are discussed. These are energy…

Medical Physics · Physics 2018-04-24 Jacobus Maarten Schippers

Proton computed tomography (CT) is similar to x-ray CT but relies on protons rather than photons to form an image. In its most common operation mode, the measured quantity is the amount of energy that a proton has lost while traversing the…

Medical Physics · Physics 2022-08-17 Nils Krah , Denis Dauvergne , Jean Michel Létang , Simon Rit , Étienne Testa

The goal of the Medium Energy Gamma-ray Astronomy (MEGA) telescope is to improve sensitivity at medium gamma-ray energies (0.4-50 MeV) by at least an order of magnitude over that of COMPTEL. This will be achieved with a new compact design…

Astrophysics · Physics 2019-08-14 P. F. Bloser , R. Andritschke , G. Kanbach , V. Schoenfelder , F. Schopper , A. Zoglauer

We are in a golden age of progress in artificial intelligence (AI). Radiotherapy, due to its technology-intensive nature as well as direct human-machine interactions, is perfectly suited for benefitting from AI to enhance accuracy and…

Medical Physics · Physics 2022-11-21 Hao Peng , Chao Wu , Dan Nguyen , Jan Schuemann , Andrea Mairani , Yuehu Pu , Steve Jiang

PANDORA, Plasmas for Astrophysics, Nuclear Decays Observation and Radiation for Archaeometry, is planned as a new facility based on a state-of-the-art plasma trap confining energetic plasma for performing interdisciplinary research in the…

Instrumentation and Detectors · Physics 2017-08-02 D. Mascali , A. Musumarra , F. Leone , F. P. Romano , A. Galatà , S. Gammino , C. Massimi

The accuracy of hadrontherapy treatment is currently limited by ion-range uncertainties. In order to fully exploit the potential of this technique, we propose the development of a novel system for online control of particle therapy, based…

The Cherenkov Telescope Array (CTA) is planned to serve as a ground-based observatory for (very-)high-energy gamma-ray astronomy, open to a wide astrophysics community, providing a deep insight into the non-thermal high-energy universe. It…

High Energy Astrophysical Phenomena · Physics 2019-08-15 M. Renaud

New particle acceleration schemes open up exciting opportunities, potentially providing more compact or higher-energy accelerators. The AWAKE experiment at CERN is currently taking data to establish the method of proton-driven plasma…

Accelerator Physics · Physics 2019-09-04 M. Wing

The energy spectrum of alpha particles from the nuclear reaction p + $^{11}$B $\rightarrow 3\alpha$ was studied using the beam of the injector of the proton synchrotron of the Prometheus proton therapy complex. The reaction products (alpha…

Purpose: Retinoblastoma (RB) is the most common eye tumor in childhood and can be treated external radiotherapy. The purpose of this work is to evaluate the adequacy of Monte Carlo simulations and the accuracy of a commercial treatment…

Medical Physics · Physics 2018-09-26 L. Brualla , P. A. Mayorga , A. Flühs , A. M. Lallena , J. Sempau , W. Sauerwein

Purpose: To evaluate reliability of upright CT for proton dose calculation and feasibility of a simplified phantom configuration for accelerated routine QA. Methods: A calibration phantom was scanned on an upright CT following consensus…

The Next-Generation Atmospheric Cherenkov Telescope Array (NG-ACTA) is proposed as a prospective infrastructure for very high energy (VHE) gamma-ray astronomy, consisting of a mixed-aperture array of 88 telescopes with a maximum array…

High Energy Astrophysical Phenomena · Physics 2026-03-23 Jiancheng Wang , Jirong Mao

It has been known for about sixty years that proton and heavy ion therapy is a very powerful radiation procedure for treating tumours. It has an innate ability to irradiate tumours with greater doses and spatial selectivity compared with…

Plasma Physics · Physics 2014-05-13 K. W. D. Ledingham , P. R. Bolton , N. Shikazono , C-M. Ma

The Cherenkov Telescope Array (CTA) will be the next generation gamma-ray observatory and will be the major global instrument for very-high-energy astronomy over the next decade, offering 5 - 10 x better flux sensitivity than current…

Instrumentation and Methods for Astrophysics · Physics 2021-08-03 J. Aschersleben , R. F. Peletier , M. Vecchi , M. H. F. Wilkinson

The Resistive Plate Chambers (RPC) are low-cost charged-particle detectors with good timing resolution and potentially good spatial resolution. Using RPC as gamma detector provides an opportunity for application in positron emission…

Instrumentation and Detectors · Physics 2014-02-20 Zhou Weizheng , Shao Ming , Li Cheng , Chen Hongfang , Sun Yongjie , Chen Tianxiang

Delineation of tumors and organs-at-risk permits detecting and correcting changes in the patients' anatomy throughout the treatment, making it a core step of adaptive proton therapy (APT). Although AI-based auto-contouring technologies have…

The electronCT technique is an imaging method based on the multiple Coulomb scattering of relativistic electrons and has potential applications in medical and industrial imaging. It utilizes a pencil beam of electrons in the very high…

An advanced Compton telescope appears to be the best instrument concept for the next generation gamma-ray space observatory in the MeV range. A first prototype of advanced Compton telescope is being developed to match the constraints of a…

Instrumentation and Methods for Astrophysics · Physics 2020-02-27 Adrien Laviron , Valentin Gourlaouen , Clarisse Hamadache , Corentin Hiver , Jürgen Kiener , Jean Peyré , Vincent Tatischeff

Proton computed tomography (pCT) is a novel imaging modality developed for patients receiving proton radiation therapy. The purpose of this work was to investigate hull-detection algorithms used for preconditioning of the large and sparse…

Computer Vision and Pattern Recognition · Computer Science 2014-02-10 Blake Schultze , Micah Witt , Yair Censor , Reinhard Schulte , Keith Evan Schubert

The two dominant radiotherapy methods are either simplified in terms of beam generation and handling, which compromises the energy deposition curve in tissues (photon therapy), or require extensive accelerator facilities and complex beam…

Accelerator Physics · Physics 2023-09-12 Marta Monikowska , Marcin Patecki
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