Related papers: A novel range telescope concept for proton CT
A prototype of proton counter was developed by the University and the National Institute for Nuclear Physics of Torino to be used as online fluence beam monitor in particle therapy. The single particle identification approach aims at…
Neutron Resonance Transmission Analysis (NRTA) is a spectroscopic technique which uses the resonant absorption of neutrons in the epithermal range to infer the isotopic composition of an object. This spectroscopic technique has relevance in…
Purpose: Photon counting (PC) computed tomography (CT) can provide material selective CT imaging at lowest patient dose but it suffers from suboptimal count rate. A dynamic beam attenuator (DBA) can help with count rate by modulating x-ray…
Positron Emission Tomography (PET) is a Nuclear Medicine technique that creates images that allow the study of metabolic activity and organ function using radiopharmaceuticals. Continuous improvement of scintillation detectors for radiation…
The physical and clinical benefits of charged particle therapy (CPT) are well recognised and recent developments have led to the rapid emergence of facilities, resulting in wider adoption worldwide. Nonetheless, the availability of CPT and…
The preliminary design of the new space gamma-ray telescope GAMMA-400 for the energy range 100 MeV - 3 TeV is presented. The angular resolution of the instrument, 1-2{\deg} at E{\gamma} ~100 MeV and ~0.01^{\circ} at E{\gamma} > 100 GeV, its…
Purpose: To improve target coverage and reduce the dose in the surrounding organs-at-risks (OARs), we developed an image-guided treatment method based on a precomputed library of treatment plans controlled and delivered in real-time.…
Photons are exponentially attenuated in matter producing high doses close to the surface. Therefore they are not well suited for the treatment of deep seated tumours. Charged particles, in contrast, exhibit a sharp increase of ionisation…
A significant number of high power proton beams are available or will go online in the near future. This provides exciting opportunities for new fixed target experiments and the search for new physics in particular. In this note we will…
Introduction: Terbium-149 ($^{149}$Tb) is a promising radionuclide for targeted $\alpha$ therapy that has a non-zero branching ratio (BR) for positron decay. However, its relatively low positron branching fraction and multiple prompt…
We recently proposed a new approach for the real-time monitoring of particle therapy treatments with the goal of achieving high sensitivities on the particle range measurement already at limited counting statistics. This method extends the…
Stereotactic body radiation therapy (SBRT) refers to focusing high-energy rays in three-dimensional space on the tumor lesion area, reducing the dose received by surrounding normal tissues, which can effectively improve the local control…
We present studies for optimizing the next generation of ground-based imaging atmospheric Cherenkov telescopes (IACTs). Results focus on mid-sized telescopes (MSTs) for CTA, detecting very high energy gamma rays in the energy range from a…
The CTA is the next generation of ground based very high energy gamma ray Imaging Atmospheric Cherenkov Telescopes. Since observations with this technique are affected by atmospheric conditions, an accurate knowledge of the atmospheric…
In this paper we investigate, with a detailed Monte-Carlo simulation based on Geant4, the novel approach [Nucl. Instrum. Methods A588 (2008) 457] to 3D imaging with photon scattering. A monochromatic and well collimated gamma beam is used…
The last 20 years have seen the development of new techniques in Astroparticle Physics providing access to the highest end of the electromagnetic spectrum. It has been shown that some sources emit photons up to energies close to 100 TeV.…
The Cherenkov Telescope Array (CTA) is the next generation observatory for very high energy gamma rays. The capability of the array to detect gamma-rays above 10 TeV is going to be achieved with a large number of Small Size Telescopes…
Computed Tomography (CT) imaging is one of the most influential diagnostic methods. In clinical reconstruction, an effective energy is used instead of total X-ray spectrum. This approximation causes an accuracy decline. To increase the…
The current generation of Imaging Atmospheric telescopes (IACTs) has demonstrated the power of this observational technique, providing high sensitivity and an angular resolution of $\sim0.1^{\circ}$ per event above an energy threshold of…
Background and purpose: IMPT faces challenges in lung cancer treatment, like maintaining plan robustness for moving tumors against setup, range errors, and interplay effects. Proton Arc Therapy (PAT) is an alternative to maintain target…