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Related papers: A novel range telescope concept for proton CT

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Intensity modulated proton therapy (IMPT) is an advanced cancer treatment modality that offers significant advantages over conventional X-ray therapies, particularly in its ability to minimize radiation dose beyond the tumor target. This…

Medical Physics · Physics 2025-08-06 Hunter D. Ellis , Imteaz Rahaman , Apostoli Hillas , Botong Li , Vikren Sarkar , Kai Fu

Charged particle beams are used in Particle Therapy (PT) to treat oncological patients due to their selective dose deposition in tissues and to their high biological effect in killing cancer cells with respect to photons and electrons used…

We compare existing segmented plastic antineutrino detectors with our new geometrically improved design for antineutrino detection and light collection efficiency. The purpose of this study is to determine the most suitable design style for…

Instrumentation and Detectors · Physics 2019-03-07 Mustafa Kandemir , Altan Cakir

Purpose: Beam angle selection is critical in proton therapy treatment planning, yet automated approaches remain underexplored. This study presents and evaluates GAMBAS, a novel, fast machine learning model for automatic beam angle…

Purpose: To measure dispersion of a clinical proton therapy beam. Methods and Materials: The proton center at our institution uses a Hitachi PROBEAT V synchrotron that delivers beams with energies ranging from 70 to 230 MeV to five…

Medical Physics · Physics 2018-05-02 Satomi Shiraishi , Michael G. Herman , Keith M. Furutani

In the context of range monitoring for particle therapy, this study presents the first experimental results obtained with the TIARA detector using carbon-ion beams at the CNAO clinical center in Pavia, Italy. TIARA is based on the Prompt…

Cosmic ray science has proved to be a very active field, with several important results from recent space-based instruments. Next generation experiments will explore the multi-TeV energy range, trying to cope with the mass and power budget…

High Energy Astrophysical Phenomena · Physics 2016-04-14 Carmelo Sgrò , Marco Incagli

Gamma-ray spectroscopy provides diagnostics of particle acceleration in solar flares, but care must be taken when interpreting the spectra due to effects of the angular distribution of the accelerated particles (such as relativistic…

Solar and Stellar Astrophysics · Physics 2015-05-20 Shichao Tang , David M. Smith

This study aims to develop a digital twin (DT) framework to enhance adaptive proton stereotactic body radiation therapy (SBRT) for prostate cancer. Prostate SBRT has emerged as a leading option for external beam radiotherapy due to its…

The current generation of Imaging Atmospheric telescopes (IACTs) has demonstrated the power of the technique in an energy range between ~100 GeV up to several tens of TeV. At the high-energy end, these instruments are limited by photon…

High Energy Astrophysical Phenomena · Physics 2009-01-21 S. Funk , J. A. Hinton

Two full rotating gantry with different nozzles (Multipurpose nozzle with MLC, Scanning Dedicated nozzle) with conventional cyclotron system is installed and under commissioning for various proton treatment options at Samsung Medical Center…

A novel dose calculation approach was designed based on the application of LSTM network that processes the 3D patient/phantom geometry as a sequence of 2D computed tomography input slices yielding a corresponding sequence of 2D slices that…

Medical Physics · Physics 2021-06-09 Ahmad Neishabouri , Niklas Wahl , Ulrich Köthe , Mark Bangert

In the last ten years the use of proton beams in radiation therapy has become a clinical tool for treatment of deep-seated tumours. LIBO is a RF compact and low cost proton linear accelerator (SCL type) for hadrontherapy. It is conceived by…

Accelerator Physics · Physics 2009-09-29 Paolo Berra

Photodynamic therapy (PDT) is a targeted cancer treatment that uses light-activated photosensitizers to generate reactive oxygen species that selectively destroy tumor cells, generally causing less collateral damage than conventional…

A new detection system KRATTA, Krak\'ow Triple Telescope Array, is presented. This versatile, low threshold, broad energy range system has been built to measure the energy, emission angle, and isotopic composition of light charged reaction…

Charged Particle Therapy is a technique for cancer treatment that exploits hadron beams, mostly protons and carbons. A critical issue is the monitoring of the dose released by the beam to the tumor and to the surrounding tissues. We present…

Photoacoustic (PA) computed tomography (PACT) shows great potentials in various preclinical and clinical applications. A great number of measurements are the premise that obtains a high-quality image, which implies a low imaging rate or a…

Computer Vision and Pattern Recognition · Computer Science 2021-06-01 Hengrong Lan , Juze Zhang , Changchun Yang , Fei Gao

The last few years have seen a revolution in very-high gamma-ray astronomy (VHE; E>100 GeV) driven largely by a new generation of Cherenkov telescopes (namely the H.E.S.S. telescope array, the MAGIC and MAGIC-II large telescopes and the…

Instrumentation and Methods for Astrophysics · Physics 2019-08-13 E. de Ona Wilhelmi , B. Rudak , J. A. Barrio , J. L. Contreras , Y. Gallant , D. Hadasch , T. Hassan , M. Lopez , D. Mazin , N. Mirabal , G. Pedaletti , M. Renaud , R. de los Reyes , D. F. Torres

Purpose: A promising approach to enable FLASH conformal proton therapy is to passively degrade a single energy layer using a patient-specific range modulator. We propose an innovative method to directly optimize the geometrical…

Medical Physics · Physics 2023-03-16 Sylvain Deffet , Kevin Souris , Edmond Sterpin