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Image denoising is a prerequisite for downstream tasks in many fields. Low-dose and photon-counting computed tomography (CT) denoising can optimize diagnostic performance at minimized radiation dose. Supervised deep denoising methods are…

Machine Learning · Computer Science 2022-01-06 Chuang Niu , Mengzhou Li , Fenglei Fan , Weiwen Wu , Xiaodong Guo , Qing Lyu , Ge Wang

We present experimental demonstration of tilt-mirror assisted transmission structured illumination microscopy (tSIM) that offers a large field of view super resolution imaging. An assembly of custom-designed tilt-mirrors are employed as the…

Super-resolution Structured Illumination Microscopy (SR-SIM) enables fluorescence microscopy beyond the diffraction limit at high frame rates. Compared to other super-resolution microscopy techniques, the low photon fluence used in SR-SIM…

Image quality is a nebulous concept with different meanings to different people. To quantify image quality a relative difference is typically calculated between a corrupted image and a ground truth image. But what metric should we use for…

Image and Video Processing · Electrical Eng. & Systems 2022-01-12 J. Kaczmar-Michalska , N. R. Hajizadeh , A. J. Rzepiela , S. F. Nørrelykke

We introduce a microscopy technique that facilitates the prediction of spatial features of chirality of nanoscale samples by exploiting photo-induced optical force exerted on an achiral tip in the vicinity of the test specimen. The…

The blind structured illumination microscopy (SIM) strategy proposed in (Mudry et al., 1992) is fully re-founded in this paper, unveiling the central role of the sparsity of the illumination patterns in the mechanism that drives…

Data Analysis, Statistics and Probability · Physics 2017-04-26 Simon Labouesse , Awoke Negash , Jérôme Idier , Sébastien Bourguignon , Thomas Mangeat , Penghuan Liu , Anne Sentenac , Marc Allain

Chiral spectroscopy is a powerful technique that enables to identify the chirality of matter through optical means. So far, experiments to check the chirality of matter or nanostructures have been carried out using free-space propagating…

Optics · Physics 2019-11-26 J. Enrique Vázquez-Lozano , Alejandro Martínez

Here, we reported, for the first time, a chiral metasurface with multifunctional capabilities tailored for the near-infrared (NIR) wavelength range, garnering tremendous interest in applications such as optical communication and chiral…

Optics · Physics 2025-06-12 Md. Ehsanul Karim , Ahmed Zubair

Though structured illumination (SI) microscopy is a popular imaging technique conventionally associated with fluorescent super-resolution, recent works have suggested its applicability towards sub-diffraction coherent imaging with…

Quantitative Methods · Quantitative Biology 2024-12-13 Shwetadwip Chowdhury , Will J. Eldridge , Adam Wax , Joseph A. Izatt

Chirality is ubiquitous in nature and fundamental in science, from particle physics to metamaterials.The most established technique of chiral discrimination - photoabsorption circular dichroism - relies on the magnetic properties of a…

The spin-selective reflection to introduce chirality which can have a lot of applications in real life such as spectroscopy, optical setups, media industry etc. In this paper, a reflection based metasurface proposed to introduce the giant…

Optics · Physics 2023-02-23 Asif Ali , Syeda Rida Tahir , Muhammad Adnan

Fluorescence microscopy is a key driver to promote discoveries of biomedical research. However, with the limitation of microscope hardware and characteristics of the observed samples, the fluorescence microscopy images are susceptible to…

Image and Video Processing · Electrical Eng. & Systems 2022-09-15 Xuanyu Tian , Qing Wu , Hongjiang Wei , Yuyao Zhang

Fourier ptychographic microscopy (FPM) is a recently proposed computational imaging technique with both high resolution and wide field-of-view. In current FP experimental setup, the dark-field images with high-angle illuminations are easily…

Computer Vision and Pattern Recognition · Computer Science 2017-12-19 Yan Zhang , An Pan , Ming Lei , Baoli Yao

Addressing the issues of severe noise and high frequency structural degradation in visible images under low-light conditions, this paper proposes a Near Infrared (NIR) aided low light image restoration method based on Frequency Decoupled…

Computer Vision and Pattern Recognition · Computer Science 2026-04-21 Ligen Shi , Zengyu Pang , Chang Liu , Shuchen Sun , Jun Qiu

Recent progress in the application of color centers to nanoscale spin sensing makes the combined use of noise spectroscopy and scanning probe imaging an attractive route for the characterization of arbitrary material systems. Unfortunately,…

The speed and quality of single-pixel imaging (SPI) are fundamentally limited by image modulation frequency and by the levels of optical noise and compression noise. In an approach to come close to these limits, we introduce a SPI…

Optics · Physics 2022-05-25 Anna Pastuszczak , Rafał Stojek , Piotr Wróbel , Rafał Kotyński

By exploiting the nonlinear responses of the fluorescent probes, the spatial resolution of structured illumination microscopy(SIM) can be further increased. However, due to the complex reconstruction process, the traditional reconstruction…

In Fourier-based medical imaging, sampling below the Nyquist rate results in an underdetermined system, in which linear reconstructions will exhibit artifacts. Another consequence of under-sampling is lower signal to noise ratio (SNR) due…

Computer Vision and Pattern Recognition · Computer Science 2016-10-04 Patrick Virtue , Michael Lustig

Structured illumination microscopy (SIM) achieves doubled spatial resolution by exciting the specimen with a high-contrast, high-frequency sinusoidal pattern. Such an excitation pattern can be generated by interference between multiple…

Optics · Physics 2020-07-15 Meiqi Li , Yaning Li , Wenhui Liu , Karl Zhanghao , Peng Xi

Fluorescence lifetime imaging microscopy (FLIM) systems are limited by their slow processing speed, low signal-to-noise ratio (SNR), and expensive and challenging hardware setups. In this work, we demonstrate applying a denoising…

Image and Video Processing · Electrical Eng. & Systems 2021-06-09 Varun Mannam , Yide Zhang , Xiaotong Yuan , Takashi Hato , Pierre C. Dagher , Evan L. Nichols , Cody J. Smith , Kenneth W. Dunn , Scott Howard