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Fluorescence Correlation Spectroscopy (FCS) yields measurement parameters (number of molecules, diffusion time) that characterize the concentration and kinetics of fluorescent molecules within a supposedly known observation volume. Absolute…
Ultralight axion or axionlike particles are one of the most promising candidates for dark matter because they are a well-motivated solution for the theoretical strong $CP$ problem and observational issues on small scales, i.e. the core-cusp…
Atomic force microscope (AFM) generally works on the basis of manipulating absolute magnitude of van der Waals (vdW) force between the tip and specimen. The force is, however, less sensitive to alternation of atom species than to tip-sample…
We demonstrate volumetric fluorescence lifetime microscopy (FLIM) using the electro-optic FLIM technique. Images acquired in a selective plane illumination microscope are gated using a Pockels cell driven at 80 MHz, enabling light sheet…
The Maxwell's fisheye (MFE) lens, due to its focusing properties, is an interesting candidate for implementing the crossing of multiple waveguides. The MFE lens is implemented by two different structures: concentric cylindrical multilayer…
Conventional microscope objective lenses are diffraction limited, which means that they cannot resolve features smaller than half the illumination wavelength. Under white light illumination, such resolution limit is about 250-300 nm for an…
The technique of remote refocusing is used in optical microscopy to provide rapid axial scanning without mechanically perturbing the sample and in techniques such as oblique plane microscopy that build on remote refocusing to image a tilted…
Photoacoustic microscopy is becoming an important tool for the biomedical research. It has been widely used in biological researches, such as structural imaging of vasculature, brain structural and functional imaging, and tumor detection.…
An azimuthally electric-polarized vector beam (APB), with a polarization vortex, has a salient feature that it contains a magnetic-dominant region within which electric field ideally has a null while longitudinal magnetic field is maximum.…
Photoacoustic microscopy with large depth of focus is significant to the biomedical research. The conventional optical-resolution photoacoustic microscope (OR-PAM) suffers from limited depth of field (DoF) since the employed focused…
Miniature fluorescence microscopes are a standard tool in systems biology. However, widefield miniature microscopes capture only 2D information, and modifications that enable 3D capabilities increase the size and weight and have poor…
Developing a chip-based super-resolution imaging technique with large field-of-view (FOV), deep subwavelength resolution, and compatibility for both fluorescent and non-fluorescent samples is desired for material science, biomedicine, and…
The main advantage of two-photon fluorescence confocal microscopy is the low absorption obtained with live tissues at the wavelengths of operation. However, the resolution of two-photon fluorescence confocal microscopes is lower than in the…
Overlapping object perception aims to decouple the randomly overlapping foreground-background features, extracting foreground features while suppressing background features, which holds significant application value in fields such as…
To effectively apply passive speckle reduction methods, it is essential to use an illumination system that maximally exploits the non-ideal temporal coherence and angular diversity (spatial coherence reduction) of laser light. This study…
The small correction volume for conventional wavefront shaping methods limits their applications in biological imaging through scattering media. We demonstrate large volume wavefront shaping through a scattering layer with a single…
We introduce the use of a crossed pair of Multilayer Laue Lenses (MLLs) as an objective in Dark-Field X-ray Microscopy (DFXM). In a demonstration experiment at the ID03 beamline at ESRF, two flat Mo-Si MLLs were used, with a physical…
Point-scanning microscopy approaches are transforming super-resolution imaging. Despite achieving parallel high-speed imaging using multifocal techniques, efficient multi-color capability with high-quality illumination is currently lacking.…
Microscale imaging of mesoscale bulk materials under dynamic compression is important for understanding their properties. In this work, we study the effects of the depth of field (DoF) and field of view (FoV) of the optical lens and extract…
Gravitational lensing allows us to probe the structure of matter on a broad range of astronomical scales, and as light from a distant source traverses an intervening galaxy, compact matter such as planets, stars, and black holes act as…