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Related papers: Time-Resolved Focused Ion Beam Microscopy: Modelin…

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Focused ion beam (FIB) microscopy suffers from source shot noise - random variation in the number of incident ions in any fixed dwell time - along with random variation in the number of detected secondary electrons per incident ion. This…

Materials Science · Physics 2026-03-12 Minxu Peng , John Murray-Bruce , Karl K. Berggren , Vivek K Goyal

Particle beam microscopy (PBM) performs nanoscale imaging by pixelwise capture of scalar values representing noisy measurements of the response from secondary electrons (SEs) integrated over a dwell time. Extended to metrology, goals…

Data Analysis, Statistics and Probability · Physics 2023-08-15 Akshay Agarwal , Minxu Peng , Vivek K. Goyal

Modern science is dependent on imaging on the nanoscale, often achieved through processes that detect secondary electrons created by a highly focused incident charged particle beam. Multiple types of measurement noise limit the ultimate…

Focused Ion Beam Scanning Electron Microscope (FIB-SEM) imaging is a technique that image materials section-by-section at nano-resolution, e.g.,5 nanometer width voxels. FIB-SEM is well suited for imaging ultrastructures in cells.…

Quantitative Methods · Quantitative Biology 2020-08-06 Hans Jacob Teglbjærg Stephensen , Sune Darkner , Jon Sporring

Particle beam microscopy uses a scanning beam of charged particles to create images of samples, and the quality of image reconstruction suffers when this beam current varies over time. Neither conventional reconstruction methods nor…

Image and Video Processing · Electrical Eng. & Systems 2021-06-10 Luisa Watkins

In a particle beam microscope, a raster-scanned focused beam of particles interacts with a sample to generate a secondary electron (SE) signal pixel by pixel. Conventionally formed micrographs are noisy because of limitations on acquisition…

Medical Physics · Physics 2023-08-15 Minxu Peng , Ruangrawee Kitichotkul , Sheila W. Seidel , Christopher Yu , Vivek K Goyal

This study presents a detailed examination of the lattice distortions introduced by glancing incidence Focussed Ion Beam (FIB) milling. Using non-destructive multi-reflection Bragg coherent X-ray diffraction we probe damage formation in an…

Materials Science · Physics 2017-11-29 Felix Hofmann , Ross J. Harder , Wenjun Liu , Yuzi Liu , Ian K Robinson , Yevhen Zayachuk

Focussed Ion Beam (FIB) milling is a mainstay of nano-scale machining. By manipulating a tightly focussed beam of energetic ions, often gallium (Ga+), FIB can sculpt nanostructures via localised sputtering. This ability to cut solid matter…

A new methodology for fundamental studies of radiation effects in solids is herein introduced by using a plasma Focused Ion Beam (PFIB). The classical example of ion-induced amorphization of single-crystalline pure Si is used as a…

Materials Science · Physics 2022-09-09 M. A. Tunes , M. M. Schneider , C. A. Taylor , T. A. Saleh

Focused ion beam (FIB) techniques are commonly used to machine, analyse and image materials at the micro- and nanoscale. However, FIB modifies the integrity of the sample by creating defects that cause lattice distortions. Methods have been…

Materials Science · Physics 2021-03-05 David Yang , Nicholas W. Phillips , Kay Song , Ross J. Harder , Wonsuk Cha , Felix Hofmann

This paper introduces a new scheme of ion beam figuring (IBF), or rather variable-spot IBF, which is conducted at a constant scanning velocity with variable-spot ion beam collimated by a variable diaphragm. It aims at improving the…

Instrumentation and Detectors · Physics 2016-02-17 Lixiang Wu , Keqiang Qiu , Shaojun Fu

The focused ion beam (FIB) is a powerful tool for the fabrication, modification and characterization of materials down to the nanoscale. Starting with the gallium FIB, which was originally intended for photomask repair in the semiconductor…

Microscope mode imaging for secondary ion mass spectrometry is a technique with the promise of simultaneous high spatial resolution and high speed imaging of biomolecules from complex surfaces. Technological developments such as new…

Instrumentation and Detectors · Physics 2013-09-05 András Kiss , Donald F. Smith , Julia H. Jungmann , Ron M. A. Heeren

Focused ion beams (FIBs) are widely used in nanofabrication for applications such as circuit repair, ultra-thin lamella preparation, strain engineering, and quantum device prototyping. Although the lateral spread of the ion beam is often…

Instrumentation and Detectors · Physics 2025-11-04 M. G. Masteghin , Z. P. Aslam , A. P. Brown , M. J. Whiting , S. K. Clowes , R. P. Webb , D. C. Cox

Cryo Focused Ion-Beam Scanning Electron Microscopy (cryo FIB-SEM) enables three-dimensional and nanoscale imaging of biological specimens via a slice and view mechanism. The FIB-SEM experiments are, however, limited by a slow (typically,…

In conventional particle beam microscopy, knowledge of the beam current is essential for accurate micrograph formation and sample milling. This generally necessitates offline calibration of the instrument. In this work, we establish that…

Medical Physics · Physics 2026-03-12 Sheila W. Seidel , Luisa Watkins , Minxu Peng , Akshay Agarwal , Christopher Yu , Vivek K Goyal

The rise of nanotechnology has created an ever-increasing need to probe structures on the atomic scale, to which transmission electron microscopy has largely been the answer. Currently, the only way to efficiently thin arbitrary bulk…

Materials Science · Physics 2015-03-19 Eero Holmström , Jani Kotakoski , Lorenz Lechner , Ute Kaiser , Kai Nordlund

In-vacuum active pixel detectors enable high sensitivity, highly parallel time- and space-resolved detection of ions from complex surfaces. For the first time, a Timepix detector assembly was combined with a Secondary Ion Mass Spectrometer…

Instrumentation and Detectors · Physics 2013-09-05 András Kiss , Julia H. Jungmann , Donald F. Smith , Ron M. A. Heeren

Scanning ion microscopy applications of novel focused ion beam (FIB) systems based on ultracold rubidium (Rb) and cesium (Cs) atoms were investigated via ion-induced electron and ion yields. Results measured on the Rb$^+$ and Cs$^+$ FIB…

Instrumentation and Detectors · Physics 2024-03-11 Y. Li , S. Xu , T. H. Loeber , E. J. D. Vredenbregt

The microlensing effect has developed into a powerful technique for a diverse range of applications including exoplanet discoveries, structure of the Milky Way, constraints on MAssive Compact Halo Objects, and measurements of the size and…

Astrophysics of Galaxies · Physics 2021-12-22 Xuechun Chen , Yiping Shu , Guoliang Li , Wenwen Zheng
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