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This paper is the third part of a trilogy dealing with the principles, performance and limitations of what I named "Telescope-Interferometers" (TIs). The basic idea consists in transforming one telescope into a Wavefront Error (WFE) sensing…

Optics · Physics 2011-05-17 Francois Henault

The non-interference three-dimensional refractive index(RI) tomography has attracted extensive attention in the life science field for its simple system implementation and robust imaging performance. However, the complexity inherent in the…

Optics · Physics 2023-06-13 Delong Yang , Shaohui Zhang , Yao Hu , Qun Hao

Cathodoluminescence (CL) has evolved into a standard analytical technique in (scanning) transmission electron microscopy. CL utilizes light excited due to the interactions between the electron-beam and the sample. In the present study we…

Applied Physics · Physics 2020-05-01 Michael Stöger-Pollach , Stefan Löffler , Niklas Maurer , Kristyna Bukvisova

IRIS is a near-infrared (0.84 to 2.4 microns) integral field spectrograph and wide-field imager being developed for first light with the Thirty Meter (TMT). It mounts to the advanced optics (AO) system NFIRAOS and has integrated…

Understanding the extent of contact between objects is crucial for surface-driven phenomena in the natural world. While interactions are known to occur at subnanometer-length scales, the techniques needed to measure such small-length scales…

Soft Condensed Matter · Physics 2024-02-21 Utkarsh Patil , Stephen Merriman , Shubhendu Kumar , Ali Dhinojwala

We present the efficiency of near-infrared reflective ruled diffraction gratings designed for the InfraRed Imaging Spectrograph (IRIS). IRIS is a first light, integral field spectrograph and imager for the Thirty Meter Telescope (TMT) and…

Instrumentation and Methods for Astrophysics · Physics 2015-06-22 Elliot Meyer , Shaojie Chen , Shelley A. Wright , Anna M. Moore , James E. Larkin , Luc Simard , Jerome Maire , Etsuko Mieda , Jacob Gordon

Numerous molecules exhibit unique absorption bands in the fingerprint infrared (IR) region, allowing chemical identification and detection. This makes IR spectroscopy an essential tool in biomedical diagnostics, sensing, and material…

Optics · Physics 2022-02-04 Anna V. Paterova , Zi S. D. Toa , Hongzhi Yang , Leonid A. Krivitsky

We present a robust, precise, and accurate method to simultaneously measure the refractive indices of two transparent materials within an interference coating. This is achieved by measuring both a photometrically accurate transmittance…

Optical fibre-based sensors measuring refractive index shift in bodily fluids and tissues are versatile and accurate probes of physiological processes. Here, we suggest a refractive index sensor based on a microstructured exposed-core fibre…

Fluorescence microscopy is widely used in biological imaging, however scattering from tissues strongly limits its applicability to a shallow depth. In this work we adapt a methodology inspired from stellar speckle interferometry, and…

A major open challenge in neuroscience is the ability to measure and perturb neural activity in vivo from well-defined neural sub-populations at cellular resolution anywhere in the brain. However, limitations posed by scattering and…

Biological Physics · Physics 2017-11-10 Shay Ohayon , Antonio Miguel Caravaca-Aguirre , Rafael Piestun , James J. DiCarlo

Intensity diffraction tomography (IDT) refers to a class of optical microscopy techniques for imaging the 3D refractive index (RI) distribution of a sample from a set of 2D intensity-only measurements. The reconstruction of artifact-free RI…

Image and Video Processing · Electrical Eng. & Systems 2022-08-16 Renhao Liu , Yu Sun , Jiabei Zhu , Lei Tian , Ulugbek Kamilov

Here, we present a novel microscopic technique for measuring wavelength-dependent three-dimensional (3-D) distributions of the refractive indices (RIs) of microscopic samples in the visible wavelengths. Employing 3-D quantitative phase…

Optics · Physics 2016-04-20 JaeHwang Jung , Kyoohyun Kim , Jonghee Yoon , YongKeun Park

A micro-ring-resonator (MRR) optical biosensor based on the evanescent field sensing mechanism has been extensively studied due to its high sensitivity and compact device size. However, a suitable on-chip integrated spectrometer device has…

Optics · Physics 2022-07-19 Kyoung Min Yoo , May Hlaing , Sourabh Jain , James Fan , Yue An , Ray T. Chen

Most integrated evanescent-field photonic sensors measure changes in either the real part or the imaginary part of the complex refractive index of the sample, i.e., refraction or absorption. Here we propose and experimentally demonstrate a…

Mid-infrared photothermal microscopy is a new chemical imaging technology in which a visible beam senses the photothermal effect induced by a pulsed infrared laser. This technology provides infrared spectroscopic information at sub-micron…

Optics · Physics 2021-04-08 Yi Zhang , Haonan Zong , Cheng Zong , Yuying Tan , Meng Zhang , Yuewei Zhan , Ji-Xin Cheng

Infrared (IR) spectroscopy has emerged as a pivotal tool in biomedical diagnostics, offering label-free spectral biomarkers for the detection of numerous diseases, particularly in the fingerprint region. However, the lack of rapid and…

Optics · Physics 2026-01-12 Xiangyu Zhao , Yuqing Liu , Jingzhu Shao , Longsheng Fang , Chongzhao Wu

An interferometric fluorescent microscope and a novel theoretic image reconstruction approach were developed and used to obtain super-resolution images of live biological samples and to enable dynamic real time tracking. The tracking…

Determination of refractive index of micro-disks of a calcinated ($1100^\circ$C in air) photo-resist SZ2080$^\mathrm{TM}$ was carried out using transmission and reflection spectroscopy. Interference fringes at specific…

Stimulated Raman scattering (SRS) microscopy offers great potential to surpass fluorescent-based approaches, owing to the sharp linewidth of Raman vibrations amenable to super-multiplex cell imaging, but currently lacks one crucial…