English

Hyperspectral optical diffraction tomography

Optics 2016-04-20 v1

Abstract

Here, we present a novel microscopic technique for measuring wavelength-dependent three-dimensional (3-D) distributions of the refractive indices (RIs) of microscopic samples in the visible wavelengths. Employing 3-D quantitative phase microscopy techniques with a wavelength-swept source, 3-D RI tomograms were obtained in the range of 450 - 700 nm with a spectral resolution of a few nanometers. The capability of the technique was demonstrated by measuring the hyperspectral 3-D RI tomograms of polystyrene beads, human red blood cells, and hepatocytes. The results demonstrate the potential for label-free molecular specific 3-D tomography of biological samples.

Keywords

Cite

@article{arxiv.1511.01651,
  title  = {Hyperspectral optical diffraction tomography},
  author = {JaeHwang Jung and Kyoohyun Kim and Jonghee Yoon and YongKeun Park},
  journal= {arXiv preprint arXiv:1511.01651},
  year   = {2016}
}
R2 v1 2026-06-22T11:38:06.721Z