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A moving boundary problem with two free boundaries modeling a two-dimensional idealized MEMS device with pull-in instability is discussed. We use a fixed point argument to show that the model possesses stationary solutions for small source…
We introduce and analyze a nonlocal version of the one-phase Stefan problem in which, as in the classical model, the rate of growth of the volume of the liquid phase is proportional to the rate at which energy is lost through the…
In this paper, we study the tumor growth equation along with various models for the nutrient component, including the \emph{in vitro} model and the \emph{in vivo} model. At the cell density level, the spatial availability of the tumor…
The existence of stationary radial solutions to a partial differential equation arising in the theory of epitaxial growth is studied. Our results depend on the size of a parameter that plays the role of the velocity at which mass is…
We consider a non-local tumour growth model of phase-field type, describing the evolution of tumour cells through proliferation in presence of a nutrient. The model consists of a coupled system, incorporating a non-local Cahn-Hilliard…
We consider the symmetry-breaking steady state bifurcation of a spatially-uniform equilibrium solution of E(2)-equivariant PDEs. We restrict the space of solutions to those that are doubly-periodic with respect to a square or hexagonal…
Tumor growth has a number of features in common with a physical process known as molecular beam epitaxy. Both growth processes are characterized by the constraint of growth development to the body border, and surface diffusion of…
We investigate the stability and global existence of weak solutions to a free boundary problem governing the evolution of polymeric fluids. We construct weak solutions of the two-phase model by performing the asymptotic limit of a…
A one-dimensional continuum-mechanical model of axonal elongation due to assembly of tubulin dimers in the growth cone is presented. The conservation of mass leads to a coupled system of three differential equations. A partial differential…
Signaling molecules play an important role for many cellular functions. We investigate here a general system of two membrane reaction-diffusion equations coupled to a diffusion equation inside the cell by a Robin-type boundary condition and…
We consider motility of keratocyte cells driven by myosin contraction and introduce a 2D free boundary model for such motion. This model generalizes a 1D model from [12] by combining a 2D Keller-Segel model and a Hele-Shaw type boundary…
Cell proliferation and diffusion can be modeled through reaction-diffusion systems describing the space-time evolution of a density variable. In this work, we present non-linear transformations of heat equation solutions to model cellular…
We consider a parabolic non-local free boundary problem that has been derived as a limit of a bulk-surface reaction-diffusion system which models cell polarization. The authors have justified the well-posedness of this problem and have…
This paper presents a mathematical framework for optimizing drug delivery in cancer treatment using a nonlocal model of solid tumor growth. We present a coupled system of partial differential equations that incorporate long-range cellular…
We study the rhomboidal symmetric-mass 4-body problem in both a two-degree-of-freedom and a four-degree-of-freedom setting. Under suitable changes of variables in both settings, isolated binary collisions at the origin are regularizable.…
In this paper, we study a phase-space analysis of a mathematical model of tumor growth with an immune response. Mathematical analysis of the model equations with multipoint initial condition, regarding to dissipativity, boundedness of…
We study an incompressible Darcy's free boundary problem, recently introduced in [22]. Our goal is to prove the existence of non-trivial traveling wave solutions and thus validate the interest of this model to describe cell motility. The…
In this paper, we study a distributed optimal control problem for a diffuse interface model for tumor growth. The model consists of a Cahn-Hilliard type equation for the phase field variable coupled to a reaction diffusion equation for the…
The hard phase model describes a relativistic barotropic fluid with sound speed equal to the speed of light. In the framework of general relativity, the motion of the fluid is coupled to the Einstein equations which describe the structure…
A free boundary value problem related to the genesis of multispecies granular biofilms is presented. The granular biofilm is modelled as a spherical free boundary domain with radial symmetry. The proposed model is conceived in the framework…