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We consider the one-phase Stefan problem describing the evolution of melting ice. On the one hand, we focus on understanding the evolution of the free boundary near isolated singular points, and we establish for the first time upper and…

Analysis of PDEs · Mathematics 2026-02-02 Gabriele Fioravanti , Xavier Ros-Oton , Clara Torres-Latorre

During the last decades, medical observations and multiscale data concerning tumor growth are mounting. At the same time, contemporary imaging techniques well established in clinical practice, provide a variety of information on real-time,…

Tissues and Organs · Quantitative Biology 2017-12-11 Markos Antonopoulos , Georgios Stamatakos

We investigate a partial differential equation model of a cancer cell population, which is structured with respect to age and telomere length of cells. We assume a continuous telomere length structure, which is applicable to the clonal…

Analysis of PDEs · Mathematics 2019-03-06 József Z. Farkas , Glenn F. Webb

Solid tumours have the ability to assemble their own vascular network for optimizing their access to the vital nutrients. These new capillaries are morphologically different from normal physiological vessels. In particular, they have a much…

Soft Condensed Matter · Physics 2022-12-07 Davide Riccobelli , Pasquale Ciarletta

We present the formal geometric derivation of a nonequilibrium growth model that takes the form of a parabolic partial differential equation. Subsequently, we study its stationary radial solutions by means of variational techniques. Our…

Classical Analysis and ODEs · Mathematics 2013-09-24 Carlos Escudero , Robert Hakl , Ireneo Peral , Pedro J. Torres

We consider the Rayleigh-Taylor problem for two compressible, immiscible, inviscid, barotropic fluids evolving with a free interface in the presence of a uniform gravitational field. After constructing Rayleigh-Taylor steady-state solutions…

Analysis of PDEs · Mathematics 2011-02-24 Yan Guo , Ian Tice

In this paper we are concerned with singular points of solutions to the {\it unstable} free boundary problem $$ \Delta u = - \chi_{\{u>0\}} \qquad \hbox{in} B_1. $$ The problem arises in applications such as solid combustion, composite…

Analysis of PDEs · Mathematics 2010-05-24 John Andersson , Henrik Shahgholian , Georg S. Weiss

We present a phase-space analysis of a mathematical model of tumor growth with an immune responses. We consider mathematical analysis of the model equations with multipoint initial condition regarding to dissipativity, boundedness of…

Dynamical Systems · Mathematics 2019-02-28 Veli Shakhmurov , Rishad Shahmurov

An individual-based model of stochastic branching is proposed and studied, in which point particles drift in $\bar{\mathds{R}}_{+}:=[0,+\infty)$ towards the origin (edge) with unit speed, where each of them splits into two particles that…

Dynamical Systems · Mathematics 2019-10-30 Yuri Kozitsky

Roll solutions at the zigzag boundary, typically selected by patterns and defects in numerical simulations, are shown to be nonlinearly stable. This result also serves as an example that linear decay weaker than the classical diffusive…

Pattern Formation and Solitons · Physics 2024-11-13 Abhijit Chowdhary , Mason Haberle , William Ofori-atta , Qiliang Wu

In this paper we consider two diffuse interface models for tumor growth coupling a Cahn-Hilliard type equation for the tumor phase parameter to a reaction-diffusion type equation for the nutrient. The models are distinguished by the…

Analysis of PDEs · Mathematics 2024-07-31 Filippo Riva , Elisabetta Rocca

We present a mathematical model that describes how tumour heterogeneity evolves in a tissue slice that is oxygenated by a single blood vessel. Phenotype is identified with the stemness level of a cell, $s$, that determines its proliferative…

Cell Behavior · Quantitative Biology 2023-11-14 Giulia L. Celora , Helen M. Byrne , P. G. Kevrekidis

We investigate a multiphase Cahn-Hilliard model for tumor growth with general source terms. The multiphase approach allows us to consider multiple cell types and multiple chemical species (oxygen and/or nutrients) that are consumed by the…

Analysis of PDEs · Mathematics 2022-06-22 Patrik Knopf , Andrea Signori

A stochastic partial differential equation along the lines of the Kardar-Parisi-Zhang equation is introduced for the evolution of a growing interface in a radial geometry. Regular polygon solutions as well as radially symmetric solutions…

Statistical Mechanics · Physics 2015-06-25 M. T. Batchelor , B. I. Henry , S. D. Watt

We introduce a free boundary model to example the effect of vesicle transport onto neurite growth. It consists of systems of drift-diffusion equations describing the evolution of the density of antero- and retrograde vesicles in each…

Analysis of PDEs · Mathematics 2025-11-26 Greta Marino , Jan-Frederik Pietschmann , Max Winkler

We study the mathematical properties of a model of cell division structured by two variables, the size and the size increment, in the case of a linear growth rate and a self-similar fragmentation kernel. We first show that one can construct…

Analysis of PDEs · Mathematics 2019-03-13 Pierre Gabriel , Hugo Martin

Williams and Bjerknes proposed a simple stochastic growth model to describe the tumor growth in the basal layer of an epithelium. In this work we generalize this model by including the possibility of saturation in the tumor growth as it is…

Condensed Matter · Physics 2007-05-23 S. C. Ferreira Junior

In this work, we present and analyze a mathematical model for tumor growth incorporating ECM erosion, interstitial flow, and the effect of vascular flow and nutrient transport. The model is of phase-field or diffused-interface type in which…

Analysis of PDEs · Mathematics 2021-06-23 Marvin Fritz , Prashant K. Jha , Tobias Köppl , J. Tinsley Oden , Barbara Wohlmuth

This paper is devoted to the study of the stability of limit cycles of a nonlinear delay differential equation with a distributed delay. The equation arises from a model of population dynamics describing the evolution of a pluripotent stem…

Analysis of PDEs · Mathematics 2009-04-17 Mostafa Adimy , Fabien Crauste , Andrei Halanay , Mihaela Neamtu , Dumitru Opris

This paper studies an evolving bulk--surface finite element method for a model of tissue growth, which is a modification of the model of Eyles, King and Styles (2019). The model couples a Poisson equation on the domain with a forced mean…

Numerical Analysis · Mathematics 2024-01-18 Dominik Edelmann , Balázs Kovács , Christian Lubich
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