English

Geometrical approach to tumor growth

Quantitative Methods 2009-11-13 v1 Statistical Mechanics Adaptation and Self-Organizing Systems Tissues and Organs

Abstract

Tumor growth has a number of features in common with a physical process known as molecular beam epitaxy. Both growth processes are characterized by the constraint of growth development to the body border, and surface diffusion of cells/particles at the growing edge. However, tumor growth implies an approximate spherical symmetry that makes necessary a geometrical treatment of the growth equations. The basic model was introduced in a former article [C. Escudero, Phys. Rev. E 73, 020902(R) (2006)], and in the present work we extend our analysis and try to shed light on the possible geometrical principles that drive tumor growth. We present two-dimensional models that reproduce the experimental observations, and analyse the unexplored three-dimensional case, for which new conclusions on tumor growth are derived.

Keywords

Cite

@article{arxiv.q-bio/0608031,
  title  = {Geometrical approach to tumor growth},
  author = {Carlos Escudero},
  journal= {arXiv preprint arXiv:q-bio/0608031},
  year   = {2009}
}