Related papers: Identification of 11 potential malaria vaccine can…
Approximately 24 million pregnant women in Sub-Saharan Africa are at risk of suffering from pregnancy malaria complications. Mechanisms responsible for increased susceptibility to malaria in pregnant women are not fully understood. Baboons…
Plasmodium falciparum is responsible for the majority of malaria morbidity and mortality each year. Malaria transmission rates vary by location and time of year due to climate and environmental conditions. We show the impact of these…
Gaussian process (GP) based statistical surrogates are popular, inexpensive substitutes for emulating the outputs of expensive computer models that simulate real-world phenomena or complex systems. Here, we discuss the evolution of dynamic…
Plasmodium vivax is the most geographically widespread malaria parasite due to its ability to remain dormant (as a hypnozoite) in the human liver and subsequently reactivate. Given the majority of P. vivax infections are due to hypnozoite…
Predicting if red blood cells (RBC) are infected with the malaria parasite is an important problem in Pathology. Recently, supervised machine learning approaches have been used for this problem, and they have had reasonable success. In…
Plasmodium falciparum aquaglyceroporin (PfAQP) is a multifunctional membrane protein in the plasma membrane of P. falciparum, the parasite that causes the most severe form of malaria. The current literature has established the science of…
We establish some properties of a within host mathematical model of malaria proposed by Recker et al which includes the role of the immune system during the infection. The model accounts for the antigenic variation exhibited by the malaria…
One of the main causes of death around the globe is malaria. Researchers have sought to develop predictive models for malaria outbreaks based on meteorological data, climate data and the breeding cycle of Plasmodium, the causative agent of…
Many models of within-host malaria infection dynamics have been formulated since the pioneering work of Anderson et al. in 1989. Biologically, the goal of these models is to understand what governs the severity of infections, the patterns…
Mass campaigns with antimalarial drugs are potentially a powerful tool for local elimination of malaria, yet current diagnostic technologies are insufficiently sensitive to identify all individuals who harbor infections. At the same time,…
Malaria is a potentially fatal plasmodium parasite injected by female anopheles mosquitoes that infect red blood cells and millions worldwide yearly. However, specialists' manual screening in clinical practice is laborious and prone to…
Smallpox is a deadly disease that can be intentionally reintroduced into the human population as a bioweapon. While host gene expression microarray profiling can be used to detect infection, the analysis of this information using…
Indonesia holds the second-highest-ranking country for the highest number of malaria cases in Southeast Asia. A different malaria parasite semantic segmentation technique based on a deep learning approach is an alternative to reduce the…
Malaria is one of the most common diseases caused by mosquitoes and is a great public health problem worldwide. Currently, for malaria diagnosis the standard technique is microscopic examination of a stained blood film. We propose use of…
Malaria is a life threatening disease, entirely preventable and treatable, provided the currently recommended interventions are properly implemented. These interventions include vector control through the use of insecticide-treated nets…
Malaria, which primarily spreads with the bite of female anopheles mosquitos, often leads to death of people - specifically children in the age-group of 0-5 years. Clinical experts identify malaria by observing RBCs in blood smeared images…
According to the World Health Organization(WHO), malaria is estimated to have killed 627,000 people and infected over 241 million people in 2020 alone, a 12% increase from 2019. Microscopic diagnosis of blood cells is the standard testing…
Effectively determining malaria parasitemia is a critical aspect in assisting clinicians to accurately determine the severity of the disease and provide quality treatment. Microscopy applied to thick smear blood smears is the de facto…
Background Elimination of malaria can only be achieved through removal of all vectors or complete depletion of the infectious reservoir in humans. Mechanistic models can be built to synthesize diverse observations from the field collected…
Malaria control strategies aiming at reducing disease transmission intensity may impact both oocyst intensity and infection prevalence in the mosquito vector. Thus far, mathematical models failed to identify a clear relationship between…