Related papers: Identification of 11 potential malaria vaccine can…

It was proposed earlier that Pfcrmp (Plasmodium falciparum chloroquine resistance marker protein) may be the chloroquine's target protein in nucleus. In this communication, further evidence is presented to support the view that Pfcrmp may…

Malaria is the leading cause of death globally, especially in sub-Saharan African countries claiming over 400,000 deaths globally each year, underscoring the critical need for continued efforts to combat this preventable and treatable…

Plasmodium falciparum is the parasite that causes the most severe form of malaria. Currently, science has been established about its cellular structures, its metabolic processes, and even the molecular structures of its intrinsic membrane…

Malaria is the one of the leading causes of morbidity and mortality in many developing countries. The development of a highly effective and readily deployable vaccine represents a major goal for world health. There has been recent progress…

Malaria is usually diagnosed by a microbiologist by examining a small sample of blood smear. Reducing mortality from malaria infection is possible if it is diagnosed early and followed with appropriate treatment. While the WHO has set…

There has been renewed interest in the use of sporozoite-based approaches for malaria vaccination and controlled human infections, and several sets of human challenge studies have recently completed. A study undertaken in Tanzania and…

Malaria is considered one of the deadliest diseases in today world which causes thousands of deaths per year. The parasites responsible for malaria are scientifically known as Plasmodium which infects the red blood cells in human beings.…

Malaria is a serious infectious disease that is responsible for over half million deaths yearly worldwide. The major cause of these mortalities is late or inaccurate diagnosis. Manual microscopy is currently considered as the dominant…

Malaria is a major contributor to health burdens throughout the regions where it is endemic. Historically, it was believed that there was limited morbidity and essentially no mortality associated with Plasmodium vivax; however, evidence…

Plasmodium vivax is one of the most geographically widespread malaria parasites in the world due to its ability to remain dormant in the human liver as hypnozoites and subsequently reactivate after the initial infection (i.e. relapse…

Plasmodium spp. are the protozoan parasites responsible for malaria. Plasmodium spp. synthesise a biocrystal, hemozoin, which can be observed under cross-polarised light. These birefringent crystals can be seen due to different refractive…

Malaria disease is a major global health and economic development threat. It results in approximately 2.7 million deaths annually. There is currently no vaccine that has been licensed for use against malaria. Studies in animal models,…

The analysis and counting of blood cells in a microscope image can provide useful information concerning to the health of a person. In particular, morphological analysis of red blood cells deformations can effectively detect important…

Malaria is a mosquito-borne, lethal disease that affects millions and kills hundreds of thousands of people each year. In this paper, we develop a model for allocating malaria interventions across geographic regions and time, subject to…

Wuchereria bancrofti, the parasitic roundworm responsible for lymphatic filariasis, permanently disables over 36 million people and places 657 million at risk across 39 countries. A major bottleneck for drug discovery is the lack of…

Falciparum malaria is a major parasitic disease causing widespread morbidity and mortality globally. Artemisinin derivatives---the most effective and widely-used antimalarials that have helped reduce the burden of malaria by 60% in some…

Malaria remains a prevalent health concern in regions with tropical and subtropical climates. The cause of malaria is the Plasmodium parasite, which is transmitted through the bites of infected female Anopheles mosquitoes. Traditional…

Malaria remains a major health threat in low-resource regions and rapid diagnostic tests often lack the sensitivity required for early detection. To address this and help establish more sensitive testing devices, we develop a predictive…

Malaria is a serious global health problem which is especially devastating to the developing world. Mosquitoes are the carriers of the parasite responsible for the disease, and hence malaria control programs focus on controlling mosquito…

A persistent public health challenge is finding immunization schemes that are effective in combating highly mutable pathogens such as HIV and influenza viruses. To address this, we analyze a simplified model of affinity maturation, the…