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Fast frame-rates are desirable in scanning transmission electron microscopy for a number of reasons: controlling electron beam dose, capturing in-situ events or reducing the appearance of scan distortions. Whilst several strategies exist…

Instrumentation and Detectors · Physics 2023-08-09 Jonathan J. P Peters , Tiarnan Mullarkey , James A. Gott , Elizabeth Nelson , Lewys Jones

For more than a century, the diffraction limit has defined the resolution achievable by passive optical imaging systems. Although some resolution improvement can be gained through classical data processing of the image, it is limited by the…

Quantum Physics · Physics 2026-05-12 A. I. Lvovsky , Michael R. Grace , Saikat Guha , Mankei Tsang , Gerardo Adesso , Nicolas Treps

With the availability of data, hardware, software ecosystem and relevant skill sets, the machine learning community is undergoing a rapid development with new architectures and approaches appearing at high frequency every year. In this…

Machine Learning · Computer Science 2022-04-15 Peter Steinbach , Felicita Gernhardt , Mahnoor Tanveer , Steve Schmerler , Sebastian Starke

Image decomposition plays a crucial role in various computer vision tasks, enabling the analysis and manipulation of visual content at a fundamental level. Overlapping images, which occur when multiple objects or scenes partially occlude…

Computer Vision and Pattern Recognition · Computer Science 2024-06-06 Saúl Alonso-Monsalve , Davide Sgalaberna , Xingyu Zhao , Adrien Molines , Clark McGrew , André Rubbia

The challenge of imaging low-density objects in an electron microscope without causing beam damage is significant in modern TEM. This is especially true for life science imaging, where the sample, rather than the instrument, still…

Optics · Physics 2025-01-29 Francisco Vega Ibáñez , Jo Verbeeck

It is well known that the registration process is a key step for super-resolution reconstruction. In this work, we propose to use a piezoelectric system that is easily adaptable on all microscopes and telescopes for controlling accurately…

Methodology · Statistics 2014-11-04 Pierre Chainais , Aymeric Leray

Images acquired by computer vision systems under low light conditions have multiple characteristics like high noise, lousy illumination, reflectance, and bad contrast, which make object detection tasks difficult. Much work has been done to…

Computer Vision and Pattern Recognition · Computer Science 2021-08-02 Winston Chen , Tejas Shah

Super-resolution microscopy overcomes the diffraction limit of conventional light microscopy in spatial resolution. By providing novel spatial or spatio-temporal information on biological processes at nanometer resolution with molecular…

Biological Physics · Physics 2021-11-10 Tianjie Yang , Yaoru Luo , Wei Ji , Ge Yang

We show that structural information can be extracted from single molecule localization microscopy (SMLM) data. More precisely, we reinterpret SMLM data as the measures of a phaseless optical diffraction tomography system for which the…

Signal Processing · Electrical Eng. & Systems 2023-07-19 Thanh-An Pham , Emmanuel Soubies , Ferréol Soulez , Michael Unser

Diffusion models for image generation often exhibit a trade-off between perceptual sample quality and data likelihood: training objectives emphasizing high-noise denoising steps yield realistic images but poor likelihoods, whereas…

Computer Vision and Pattern Recognition · Computer Science 2025-11-25 Yasin Esfandiari , Stefan Bauer , Sebastian U. Stich , Andrea Dittadi

A class of two-bit bit flipping algorithms for decoding low-density parity-check codes over the binary symmetric channel was proposed in [1]. Initial results showed that decoders which employ a group of these algorithms operating in…

Information Theory · Computer Science 2012-05-22 Dung Viet Nguyen , Bane Vasic , Michael W. Marcellin

For more than a century and a half it has been widely-believed (but was never rigorously shown) that the physics of diffraction imposes certain fundamental limits on the resolution of an optical system. However our understanding of what…

Data Structures and Algorithms · Computer Science 2020-12-16 Sitan Chen , Ankur Moitra

We present a method that can simultaneously locate positions of overlapped multi-emitters at the theoretical-limit precision. We derive a set of simple equations whose solution gives the maximum likelihood estimator of multi-emitter…

Optics · Physics 2015-12-21 Yuto Ashida , Masahito Ueda

Fluorescence microscopy allows for a detailed inspection of cells, cellular networks, and anatomical landmarks by staining with a variety of carefully-selected markers visualized as color channels. Quantitative characterization of…

Computer Vision and Pattern Recognition · Computer Science 2021-08-26 Alvaro Gomariz , Tiziano Portenier , Patrick M. Helbling , Stephan Isringhausen , Ute Suessbier , César Nombela-Arrieta , Orcun Goksel

Precisely measuring the three-dimensional position and orientation of individual fluorophores is challenging due to the substantial photon shot noise in single-molecule experiments. Facing this limited photon budget, numerous techniques…

Optics · Physics 2021-02-02 Oumeng Zhang , Matthew D. Lew

We introduce a imaging modality that works by transiently masking image-subregions during a single exposure of a CCD frame. By offsetting subregion exposure time, temporal information is embedded within each stored frame, allowing…

Quantitative Methods · Quantitative Biology 2016-09-08 Gil Bub , Matthias Tecza , Michiel Helmes , Peter Lee , Peter Kohl

Several Scientific and engineering applications require merging of sampled images for complex perception development. In most cases, for such requirements, images are merged at intensity level. Even though it gives fairly good perception of…

Computer Vision and Pattern Recognition · Computer Science 2014-08-01 T. R. Gopalakrishnan Nair , Richa Sharma

Hyperspectral cameras face challenging spatial-spectral resolution trade-offs and are more affected by shot noise than RGB photos taken over the same total exposure time. Here, we present a colorization algorithm to reconstruct…

Computer Vision and Pattern Recognition · Computer Science 2024-03-19 M. Kerem Aydin , Qi Guo , Emma Alexander

A lensless digital holography enables wide-field microscopic imaging without the limitations imposed by optical lens performance. However, conventional holographic imaging often relies on magnifying optical systems to compensate for the low…

Optics · Physics 2025-06-24 Byung Gyu Chae

Recent advances in the technology of transmission electron microscopy have allowed for a more precise visualization of materials and physical processes, such as metal oxidation. Nevertheless, the quality of information is limited by the…

Distributed, Parallel, and Cluster Computing · Computer Science 2017-12-08 Marcin Copik
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