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Quality control in molecular optical sectioning microscopy is indispensable for transforming acquired digital images from qualitative descriptions to quantitative data. Although numerous tools, metrics, and phantoms have been developed,…

In the ELTs era, where the need for versatile and innovative solutions to produce very high spatial resolution images has become a major issue, the search of synergies with other science fields seems a logic step. One of the considered…

Instrumentation and Methods for Astrophysics · Physics 2018-11-15 E. Quevedo , S. Velasco , C. Colodro-Conde , G. Rodríguez-Coira , A. Oscoz , R. L. López , J. Font , J. H. Brito , O. Llinas , S. Robaina , G. M. Callico , R. Sarmiento , R. Rebolo

Fluorescence recovery after photobleaching (FRAP) measurements offer an important tool for analyzing diffusion and binding processes. Confocal scanning laser microscopes that are used in FRAP experiments bleach regions with a radially…

Subcellular Processes · Quantitative Biology 2009-03-09 George D Tsibidis

Sequential registering of fluorescence signals in conventional Excitation-Emission Matrices (EEMs), followed by modeling based on multilinear properties of the data, requires stable fluorophore concentrations throughout the acquisition of…

Medical Physics · Physics 2025-02-28 Gabriel Siano , Sofia Mora , Agustina Schenone , Leonardo Giovanini

Super-resolution is the process of obtaining a high-resolution image from one or more low-resolution images. Single image super-resolution (SISR) and multi-frame super-resolution (MFSR) methods have been evolved almost independently for…

Computer Vision and Pattern Recognition · Computer Science 2023-03-07 Mohammad Mahdi Afrasiabi , Reshad Hosseini , Aliazam Abbasfar

A simple, yet general, formalism for the optimized linear combination of astrophysical images is constructed and demonstrated. The formalism allows the user to combine multiple undersampled images to provide oversampled output at high…

Instrumentation and Methods for Astrophysics · Physics 2015-05-28 Barnaby Rowe , Christopher Hirata , Jason Rhodes

Widefield stochastic microscopy techniques such as PALM or STORM rely on the progressive accumulation of a large number of frames, each containing a scarce number of super-resolved point images. We justify that the redundancy in the…

Biological Physics · Physics 2017-10-11 Jean-Francois Rupprecht , Ariadna Martinez-Marrades , Rishita Changede , Gilles Tessier

We present a new method that combines fluorescence correlation spectroscopy (FCS) on the microsecond time scale with fluorescence antibunching measurements on the nanosecond time scale for measuring photophysical rate constants of…

Chemical Physics · Physics 2022-03-28 Damir Sakhapov , Ingo Gregor , Narain Karedla , Jörg Enderlein

Rapid growth in the field of quantitative digital image analysis is paving the way for researchers to make precise measurements about objects in an image. To compute quantities from the image such as the density of compressed materials or…

Computer Vision and Pattern Recognition · Computer Science 2017-07-31 Marylesa Howard , Margaret C. Hock , B. T. Meehan , Leora Dresselhaus-Cooper

High-throughput screening using cell images is an efficient method for screening new candidates for pharmaceutical drugs. To complete the screening process, it is essential to have an efficient process for analyzing cell images. This paper…

Computer Vision and Pattern Recognition · Computer Science 2024-02-28 Mizuki Fukasawa , Tomokazu Fukuda , Takuya Akashi

Image forensics has become increasingly crucial in our daily lives. Among various types of forgeries, copy-move forgery detection has received considerable attention within the academic community. Keypoint-based algorithms, particularly…

Computer Vision and Pattern Recognition · Computer Science 2024-05-01 Li Jiang , Zhaowei Lu

Optical super-resolution microscopy is a key technology for structural biology that offers high imaging contrast and live-cell compatibility. Minimal (fluorescence) photons flux microscopy, or MINFLUX, is an emerging super-resolution…

Optics · Physics 2025-08-29 Lukas Scheiderer , Zach Marin , Jonas Ries

We consider passive imaging tasks involving discrimination between known candidate objects and investigate the best possible accuracy with which the correct object can be identified. We analytically compute quantum-limited error bounds for…

Quantum Physics · Physics 2022-10-26 Michael R Grace , Saikat Guha

Fourier Ptychography is a recently proposed imaging technique that yields high-resolution images by computationally transcending the diffraction blur of an optical system. At the crux of this method is the phase retrieval algorithm, which…

Computer Vision and Pattern Recognition · Computer Science 2018-05-10 Lokesh Boominathan , Mayug Maniparambil , Honey Gupta , Rahul Baburajan , Kaushik Mitra

There exists a plethora of techniques for inducing structured sparsity in parametric models during the optimization process, with the final goal of resource-efficient inference. However, few methods target a specific number of…

Machine Learning · Computer Science 2018-11-26 Raphael Tang , Ashutosh Adhikari , Jimmy Lin

Local feature detection is a key ingredient of many image processing and computer vision applications, such as visual odometry and localization. Most existing algorithms focus on feature detection from a sharp image. They would thus have…

Computer Vision and Pattern Recognition · Computer Science 2022-11-30 Zhenjun Zhao , Yu Zhai , Ben M. Chen , Peidong Liu

Fluorescence microscopy is essential in biological and medical research, providing critical insights into cellular structures. However, limited by optical diffraction and background noise, a substantial amount of hidden information is still…

Biological Physics · Physics 2026-04-14 Xiaofeng Zhang , Yongsheng Huang , Jielong Yang , Zhili Wang , Si Chen , Linbo Liu , Xin Ge

This paper aims at addressing the problem of substantial performance degradation at extremely low computational cost (e.g. 5M FLOPs on ImageNet classification). We found that two factors, sparse connectivity and dynamic activation function,…

Computer Vision and Pattern Recognition · Computer Science 2021-08-21 Yunsheng Li , Yinpeng Chen , Xiyang Dai , Dongdong Chen , Mengchen Liu , Lu Yuan , Zicheng Liu , Lei Zhang , Nuno Vasconcelos

Diffusion models have shown great promise in synthesizing visually appealing images. However, it remains challenging to condition the synthesis at a fine-grained level, for instance, synthesizing image pixels following some generic color…

Computer Vision and Pattern Recognition · Computer Science 2025-03-11 Ka Chun Shum , Binh-Son Hua , Duc Thanh Nguyen , Sai-Kit Yeung

Image Phase Alignment Super-Sampling (ImPASS) is a computational imaging algorithm for converting a sequence of displaced low-resolution images into a single high-resolution image. The method consists of a unique combination of Phase…

Optics · Physics 2025-09-01 James N. Caron
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