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The use of fluorescent molecules to create long sequences of low-density, diffraction-limited images enables highly-precise molecule localization. However, this methodology requires lengthy imaging times, which limits the ability to view…

Image and Video Processing · Electrical Eng. & Systems 2024-03-26 Yair Ben Sahel , Yonina C. Eldar

Super-resolution localization microscopy is based on determining the positions of individual fluorescent markers in a sample. The major challenge in reaching an ever higher localization precision lies in the limited number of collected…

Optics · Physics 2020-08-05 Daniel Böning , Franz-Ferdinand Wieser , Vahid Sandoghdar

Super-resolution algorithms often struggle with images from surveillance environments due to adverse conditions such as unknown degradation, variations in pose, irregular illumination, and occlusions. However, acquiring multiple images,…

Computer Vision and Pattern Recognition · Computer Science 2024-10-22 Marcelo dos Santos , Rayson Laroca , Rafael O. Ribeiro , João C. Neves , David Menotti

With technological advances leading to an increase in mechanisms for image tampering, fraud detection methods must continue to be upgraded to match their sophistication. One problem with current methods is that they require prior knowledge…

Computer Vision and Pattern Recognition · Computer Science 2022-01-25 Robin Elizabeth Yancey

Super-resolution microscopy has catalyzed valuable insights into the sub-cellular, mechanistic details of many different biological processes across a wide range of cell types. Fluorescence polarization spectroscopy tools have also enabled…

Biological Physics · Physics 2023-01-25 Jack W Shepherd , Alex L Payne-Dwyer , Ji-Eun Lee , Aisha Syeda , Mark C Leake

Parallelism patterns (e.g., map or reduce) have proven to be effective tools for parallelizing high-performance applications. In this paper, we study the recursive registration of a series of electron microscopy images - a time consuming…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-10-26 Marcin Copik , Tobias Grosser , Torsten Hoefler , Paolo Bientinesi , Benjamin Berkels

The Cramer-Rao lower bound for the estimation of the affine transformation parameters in a multivariate heteroscedastic errors-in-variables model is derived. The model is suitable for feature-based image registration in which both sets of…

Methodology · Statistics 2015-06-30 E. A. K. Cohen , D. Kim , R. J. Ober

As electronic computing approaches its performance limits, photonic accelerators have emerged as promising alternatives. Photonic accelerators exploiting semiconductor-laser synchronization have been studied for decision-making. While…

Super-resolution light microscopy overcomes the physical barriers due to light diffraction, allowing for the observation of otherwise indistinguishable subcellular entities. However, the specific acquisition conditions required by…

The principles of difference imaging outlined and the technique of Alard and Lupton (1997) is generalised to generate the best possible difference images to within the limits of measurement error. It is shown how for a large database of…

Astrophysics · Physics 2007-05-23 Austin B. Tomaney

In traditional optical imaging systems, the spatial resolution is limited by the physics of diffraction, which acts as a low-pass filter. The information on sub-wavelength features is carried by evanescent waves, never reaching the camera,…

Optics · Physics 2018-12-13 Oren Solomon , Yonina C. Eldar , Maor Mutzafi , Mordechai Segev

Far-field characterization of small objects is severely constrained by the diffraction limit. Existing tools achieving sub-diffraction resolution often utilize point-by-point image reconstruction via scanning or labelling. Here, we present…

Analyzing microscopy images to extract biological object properties (e.g., their morphological organization, temporal dynamics, and population density) is fundamental to various biomedical research. Yet conducting this manually is costly…

Computer Vision and Pattern Recognition · Computer Science 2026-05-15 Xiaofei Hui , Haoxuan Qu , Hossein Rahmani , Shuohong Wang , Jeff W. Lichtman , Jun Liu

It is demonstrated that an object distribution can be successfully retrieved from its diffraction pattern or hologram, even if some of the measured intensity samples are missing. The maximum allowable number of missing values depends on the…

Image and Video Processing · Electrical Eng. & Systems 2019-08-28 Tatiana Latychevskaia

We propose an unfolded accelerated projected-gradient descent procedure to estimate model and algorithmic parameters for image super-resolution and molecule localization problems in image microscopy. The variational lower-level constraint…

Numerical Analysis · Mathematics 2024-03-27 Silvia Bonettini , Luca Calatroni , Danilo Pezzi , Marco Prato

X-ray ptychography is one of the versatile techniques for nanometer resolution imaging. The magnitude of the diffraction patterns is recorded on a detector and the phase of the diffraction patterns is estimated using phase retrieval…

Image and Video Processing · Electrical Eng. & Systems 2021-05-21 Prasan Shedligeri , Florian Schiffers , Semih Barutcu , Pablo Ruiz , Aggelos K Katsaggelos , Oliver Cossairt

Scalable atom-based quantum platforms for simulation, computing, and metrology require fast high-fidelity, low-loss imaging of individual atoms. Standard fluorescence detection methods rely on continuous cooling, limiting the detection…

Multi-photon microscopy has played a significant role in biological imaging since it allows to observe living tissues with improved penetration depth and excellent sectioning effect. Multi-photon microscopy relies on multi-photon…

Image deblurring is a notoriously challenging ill-posed inverse problem. In recent years, a wide variety of approaches have been proposed based upon regularization at the level of the image or on techniques from machine learning. We propose…

Computer Vision and Pattern Recognition · Computer Science 2020-10-22 Gabriel Rioux , Rustum Choksi , Tim Hoheisel , Pierre Marechal , Christopher Scarvelis

The ability to record high-fidelity videos at high acquisition rates is central to the study of fast moving phenomena. The difficulty of imaging fast moving scenes lies in a trade-off between motion blur and underexposure noise: On the one…

Computer Vision and Pattern Recognition · Computer Science 2022-11-30 Weihao Zhuang , Tristan Hascoet , Ryoichi Takashima , Tetsuya Takiguchi